AR006364A1 - Acarviosil-transferasa asi como el uso de la misma, transformacion de homologos de acarbosa en acarbosa, para la produccion de homologos deacarbosa, produccion recombinante de acarviosil-transferasa y dicho vector que la contiene. - Google Patents

Acarviosil-transferasa asi como el uso de la misma, transformacion de homologos de acarbosa en acarbosa, para la produccion de homologos deacarbosa, produccion recombinante de acarviosil-transferasa y dicho vector que la contiene.

Info

Publication number
AR006364A1
AR006364A1 ARP970101167A ARP970101167A AR006364A1 AR 006364 A1 AR006364 A1 AR 006364A1 AR P970101167 A ARP970101167 A AR P970101167A AR P970101167 A ARP970101167 A AR P970101167A AR 006364 A1 AR006364 A1 AR 006364A1
Authority
AR
Argentina
Prior art keywords
acarbose
transferase
approvals
production
acarviosyl
Prior art date
Application number
ARP970101167A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR006364A1 publication Critical patent/AR006364A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se refiere a la acarviosil-transferasa de Actinomicetes, principalmente de especies Actinoplanetes SE50/110 y sus mutantes, un procedimiento parala transformación de componentes menores de acarbosa, a la expresión de la acarviosil-transferasa en un organismo hospedador heterólogo, al uso de laacarviosil-transferasa para la transformación de componentes derivados de acarbosa en acarbosa o bien para la producción de homólogos de la acarbosa,al uso de la acarviosil-transferasa en lapurificación de acarbosa, así como a la obtención de mutantes productivos con formación de componentesderivados reducida mediante inactivación del gen de la acarviosil-transferasa.
ARP970101167A 1996-03-22 1997-03-21 Acarviosil-transferasa asi como el uso de la misma, transformacion de homologos de acarbosa en acarbosa, para la produccion de homologos deacarbosa, produccion recombinante de acarviosil-transferasa y dicho vector que la contiene. AR006364A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19611252 1996-03-22
DE19625269A DE19625269A1 (de) 1996-03-22 1996-06-25 Acarviosyl-Transferase aus Actinoplanes sp. SE 50/110 und -Mutanten, Verfahren zur Herstellung sowie zur Verwendung von Acarviosyl-Transferase bei der Umwandlung von Acarbose-Homologen in Acarbose, zur Herstellung von Acarbose-Homologen und zur Stamm-Optimierung

Publications (1)

Publication Number Publication Date
AR006364A1 true AR006364A1 (es) 1999-08-25

Family

ID=7789039

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970101167A AR006364A1 (es) 1996-03-22 1997-03-21 Acarviosil-transferasa asi como el uso de la misma, transformacion de homologos de acarbosa en acarbosa, para la produccion de homologos deacarbosa, produccion recombinante de acarviosil-transferasa y dicho vector que la contiene.

Country Status (5)

Country Link
KR (1) KR970065709A (es)
AR (1) AR006364A1 (es)
DE (1) DE19625269A1 (es)
TW (1) TW363080B (es)
ZA (1) ZA972424B (es)

Also Published As

Publication number Publication date
ZA972424B (en) 1997-09-25
TW363080B (en) 1999-07-01
DE19625269A1 (de) 1997-09-25
KR970065709A (ko) 1997-10-13

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