AR006109A1 - Implantes que entregan sustancias medicamentosas por fases - Google Patents
Implantes que entregan sustancias medicamentosas por fasesInfo
- Publication number
- AR006109A1 AR006109A1 ARP970100875A ARP970100875A AR006109A1 AR 006109 A1 AR006109 A1 AR 006109A1 AR P970100875 A ARP970100875 A AR P970100875A AR P970100875 A ARP970100875 A AR P970100875A AR 006109 A1 AR006109 A1 AR 006109A1
- Authority
- AR
- Argentina
- Prior art keywords
- implants
- drug substances
- phases
- substances
- different
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
Abstract
El campo de aplicación se encuentra en el tratamiento de enfermedades mediante implantes que liberan sustancias medicamentosas. El problemaplanteado era lograr una liberación escalonada en el tiempo, de sustancias medicamentosasdiferentes o de dosis dieferentes de una misma sustanciamedicamentosa. Este problema se resuelve con implantes que están constituidos por un núcleo y por capas dispuestas de modo concéntrico alrededor de él. Elnúcleo y al menos una de las capascontienen sus tancias medicamentosas diferentes o dosis diferentes de una misma sustancia medicamentosa. Las partesque contienen sustancia medicamentosa están formadas por materiales polímeros, biodegradables con erosión superficial.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19608423A DE19608423A1 (de) | 1996-03-05 | 1996-03-05 | Implantate mit phasenweiser Arzneistoffabgabe |
Publications (1)
Publication Number | Publication Date |
---|---|
AR006109A1 true AR006109A1 (es) | 1999-08-11 |
Family
ID=7787249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970100875A AR006109A1 (es) | 1996-03-05 | 1997-03-05 | Implantes que entregan sustancias medicamentosas por fases |
Country Status (10)
Country | Link |
---|---|
US (1) | US6086908A (es) |
EP (1) | EP0868171B1 (es) |
JP (1) | JP2000507218A (es) |
AR (1) | AR006109A1 (es) |
AT (1) | ATE231717T1 (es) |
AU (1) | AU1793497A (es) |
DE (2) | DE19608423A1 (es) |
ID (1) | ID16109A (es) |
WO (1) | WO1997032570A1 (es) |
ZA (1) | ZA971869B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9808052D0 (en) * | 1998-04-17 | 1998-06-17 | Secr Defence | Implants for administering substances and methods of producing implants |
PT1112095E (pt) * | 1998-09-11 | 2003-04-30 | Axel Stemberger | Implantes biologicamente activos |
US7666445B2 (en) * | 2000-10-20 | 2010-02-23 | The Trustees Of The University Of Pennsylvania | Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use |
CA2464653C (en) * | 2001-10-29 | 2011-10-18 | Therics, Inc. | System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing |
DE10161078A1 (de) * | 2001-12-12 | 2003-08-28 | Achim Goepferich | Matrizes zur Stabilisierung und kontrollierten Freisetzung von Problemarzneistoffen |
US20030199449A1 (en) * | 2002-04-19 | 2003-10-23 | Tarcha Peter J. | Combination of ablation and controlled drug delivery for the treatment of cancer |
CN100366249C (zh) * | 2002-09-29 | 2008-02-06 | 天津帝士力投资控股集团有限公司 | 一种替莫唑胺控释给药系统 |
US7169405B2 (en) * | 2003-08-06 | 2007-01-30 | Warsaw Orthopedic, Inc. | Methods and devices for the treatment of intervertebral discs |
US8329203B2 (en) * | 2004-01-12 | 2012-12-11 | The Trustees Of The University Of Pennsylvania | Drug-containing implants and methods of use thereof |
WO2005070332A1 (en) * | 2004-01-12 | 2005-08-04 | The Trustees Of The University Of Pennsylvania | Long-term delivery formulations and methods of use thereof |
US8221778B2 (en) | 2005-01-12 | 2012-07-17 | The Trustees Of The University Of Pennsylvania | Drug-containing implants and methods of use thereof |
WO2006078320A2 (en) | 2004-08-04 | 2006-07-27 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
WO2008121702A2 (en) * | 2007-03-28 | 2008-10-09 | Boston Scientific Scimed, Inc. | Medical devices having bioerodable layers for the release of therapeutic agents |
US8470360B2 (en) * | 2008-04-18 | 2013-06-25 | Warsaw Orthopedic, Inc. | Drug depots having different release profiles for reducing, preventing or treating pain and inflammation |
US8728528B2 (en) | 2007-12-20 | 2014-05-20 | Evonik Corporation | Process for preparing microparticles having a low residual solvent volume |
EP2259805B1 (en) * | 2008-02-29 | 2016-08-17 | Smith & Nephew, Inc. | Gradient coating for biomedical applications |
EP2427179A4 (en) | 2009-05-04 | 2013-09-11 | Psivida Inc | POROUS PARTICLES FOR THE RELEASE OF SILICIUM MEDICINES |
SG10201501964QA (en) * | 2010-03-16 | 2015-05-28 | Titan Pharmaceuticals Inc | Heterogeneous Implantable Devices For Drug Delivery |
IN2013MN00758A (es) | 2010-11-01 | 2015-06-12 | Psivida Inc | |
CA2860108C (en) | 2011-12-29 | 2016-10-04 | Laboratorios Andromaco S.A. | Vaginal ring including meloxicam and an agent for modulating the release of the active principle, which can be used as a continuous-use contraceptive in women |
JP2016512839A (ja) | 2013-03-15 | 2016-05-09 | シヴィダ・ユーエス・インコーポレイテッドPsivida Us, Inc. | 治療物質の送達のための生体内分解性ケイ素系組成物 |
CN117357712A (zh) * | 2015-02-27 | 2024-01-09 | 聚合物器官 Ip 股份有限公司 | 药物洗脱泡沫及其生产 |
EP3272333A1 (en) | 2016-07-22 | 2018-01-24 | Chemo Research, S.L. | Vaginal composition comprising a combination of estrogen and vitamin d |
CN115671379B (zh) * | 2022-10-27 | 2024-02-02 | 牛瑞瑞 | 一种医用植入物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1045977A (en) * | 1973-05-17 | 1979-01-09 | Arthur D. Little | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
US4450150A (en) * | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
IL70071A (en) * | 1982-11-01 | 1987-12-31 | Merrell Dow Pharma | Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient |
HUT69680A (en) * | 1990-08-09 | 1995-09-28 | Endocon Inc | Implant and apparatus for delivering multiple drug and process for production of theese |
-
1996
- 1996-03-05 DE DE19608423A patent/DE19608423A1/de not_active Withdrawn
-
1997
- 1997-02-20 EP EP97903343A patent/EP0868171B1/de not_active Expired - Lifetime
- 1997-02-20 WO PCT/EP1997/000820 patent/WO1997032570A1/de active IP Right Grant
- 1997-02-20 AT AT97903343T patent/ATE231717T1/de not_active IP Right Cessation
- 1997-02-20 JP JP9531399A patent/JP2000507218A/ja active Pending
- 1997-02-20 AU AU17934/97A patent/AU1793497A/en not_active Abandoned
- 1997-02-20 US US09/142,227 patent/US6086908A/en not_active Expired - Fee Related
- 1997-02-20 DE DE59709231T patent/DE59709231D1/de not_active Expired - Fee Related
- 1997-03-03 ID IDP970652A patent/ID16109A/id unknown
- 1997-03-04 ZA ZA9701869A patent/ZA971869B/xx unknown
- 1997-03-05 AR ARP970100875A patent/AR006109A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US6086908A (en) | 2000-07-11 |
JP2000507218A (ja) | 2000-06-13 |
DE59709231D1 (de) | 2003-03-06 |
DE19608423A1 (de) | 1997-09-11 |
EP0868171B1 (de) | 2003-01-29 |
ATE231717T1 (de) | 2003-02-15 |
WO1997032570A1 (de) | 1997-09-12 |
ZA971869B (en) | 1997-09-09 |
ID16109A (id) | 1997-09-04 |
AU1793497A (en) | 1997-09-22 |
EP0868171A1 (de) | 1998-10-07 |
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