SG10201501964QA - Heterogeneous Implantable Devices For Drug Delivery - Google Patents

Heterogeneous Implantable Devices For Drug Delivery

Info

Publication number
SG10201501964QA
SG10201501964QA SG10201501964QA SG10201501964QA SG10201501964QA SG 10201501964Q A SG10201501964Q A SG 10201501964QA SG 10201501964Q A SG10201501964Q A SG 10201501964QA SG 10201501964Q A SG10201501964Q A SG 10201501964QA SG 10201501964Q A SG10201501964Q A SG 10201501964QA
Authority
SG
Singapore
Prior art keywords
drug delivery
implantable devices
heterogeneous
heterogeneous implantable
devices
Prior art date
Application number
SG10201501964QA
Inventor
Rajesh A Patel
Sunil R Bhonsle
Original Assignee
Titan Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Titan Pharmaceuticals Inc filed Critical Titan Pharmaceuticals Inc
Publication of SG10201501964QA publication Critical patent/SG10201501964QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201501964QA 2010-03-16 2011-03-16 Heterogeneous Implantable Devices For Drug Delivery SG10201501964QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31446510P 2010-03-16 2010-03-16

Publications (1)

Publication Number Publication Date
SG10201501964QA true SG10201501964QA (en) 2015-05-28

Family

ID=44649589

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201501964QA SG10201501964QA (en) 2010-03-16 2011-03-16 Heterogeneous Implantable Devices For Drug Delivery
SG2012067989A SG184059A1 (en) 2010-03-16 2011-03-16 Heterogeneous implantable devices for drug delivery

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2012067989A SG184059A1 (en) 2010-03-16 2011-03-16 Heterogeneous implantable devices for drug delivery

Country Status (18)

Country Link
US (4) US10111830B2 (en)
EP (1) EP2547332B1 (en)
JP (2) JP5869551B2 (en)
KR (1) KR101914119B1 (en)
AU (1) AU2011227289B2 (en)
CA (1) CA2792179C (en)
CY (1) CY1120964T1 (en)
DK (1) DK2547332T3 (en)
ES (1) ES2699200T3 (en)
HR (1) HRP20182014T1 (en)
LT (1) LT2547332T (en)
MX (1) MX354444B (en)
PL (1) PL2547332T3 (en)
PT (1) PT2547332T (en)
RS (1) RS58011B1 (en)
SG (2) SG10201501964QA (en)
SI (1) SI2547332T1 (en)
WO (1) WO2011116132A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2792179C (en) 2010-03-16 2019-04-02 Titan Pharmaceuticals, Inc. Heterogeneous implantable devices for drug delivery
MX350469B (en) * 2011-10-24 2017-09-07 Endo Pharmaceuticals Solutions Implantable drug delivery compositions and methods of treatment thereof.
US8980298B2 (en) 2011-10-24 2015-03-17 Braeburn Pharmaceuticals Bvba Sprl Implantable tizanidine compositions and methods of treatment thereof
CA2853251A1 (en) * 2011-10-24 2013-05-02 Endo Pharmaceuticals Solutions Inc. Implantable rasagiline compositions and methods of treatment thereof
TW201332585A (en) 2012-02-14 2013-08-16 Chemo Res S L Core sheath drug delivery devices
CN102731777B (en) * 2012-07-06 2013-12-18 辽宁大学 Synthesis method of poly-benzyl L-glutamate/ethyl polyphosphate block copolymer
SG11201608483PA (en) * 2014-05-30 2016-11-29 Textile Based Delivery Inc Drug delivery systems and related methods of use
BR112017007942A2 (en) 2014-10-30 2017-12-19 Textile Based Delivery Inc release systems
KR101693696B1 (en) * 2015-06-12 2017-01-06 한국생산기술연구원 Hemostatic porous structure and process for preparing the same
PT109154B (en) * 2016-02-12 2019-11-05 Univ De Coimbra NON-INVASIVE EYE INSERT TECHNOLOGY FOR CONTROLLED DRUG RELEASE
GB201603296D0 (en) 2016-02-25 2016-04-13 Ucl Business Plc Chemotactic,drug-containing polymersomes
GB201604553D0 (en) 2016-03-17 2016-05-04 Ucl Business Plc Fumarate polymersomes
AU2017263253B2 (en) * 2016-05-12 2022-04-14 Merck Sharp & Dohme Llc Drug delivery system for the delivery of antiviral agents
JP7407595B2 (en) * 2016-10-05 2024-01-04 タイタン ファーマシューティカルズ インコーポレイテッド Implantable devices for drug delivery that reduce burst release
IT201700101582A1 (en) * 2017-09-12 2019-03-12 Milano Politecnico Device for intraocular release
CN108310455B (en) * 2018-03-20 2021-07-30 嘉兴尔云信息科技有限公司 Nano hydroxyapatite and PGS-M composite bone repair material and preparation method thereof
CN111989068A (en) * 2018-05-24 2020-11-24 塞拉尼斯伊娃高性能聚合物公司 Implantable devices for sustained release of macromolecular drug compounds
WO2019226516A1 (en) * 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
KR102183669B1 (en) * 2019-03-26 2020-11-26 가톨릭대학교 산학협력단 Drug delivery carrier for dual drug release
WO2022204771A1 (en) * 2021-03-29 2022-10-06 Edson Luiz Peracchi Long-lasting resorbable subcutaneous implant with prolonged release of pre-concentrated pharmacologically active substance in polymer for the treatment of hypothyroidism, and method
CA3174146A1 (en) * 2021-04-14 2022-10-14 Katherine BEEBE DEVARNEY Kappa-opioid receptor agonist implants for treatment of pruritus
CN113209050A (en) * 2021-05-14 2021-08-06 浙江恒冀制药有限责任公司 Long-acting in vivo skin-embedded or implanted sustained-release preparation based on biocompatible polymer
WO2023091333A1 (en) * 2021-11-17 2023-05-25 Celanese Eva Performance Polymers Llc Implantable device for treating an inflammatory eye condition
WO2023244526A1 (en) * 2022-06-13 2023-12-21 Celanese Eva Performance Polymers Llc Monolithic implantable device for sustained release of an antibody
GB202401392D0 (en) 2024-02-02 2024-03-20 Imphatec Ltd Implant for delivery of a drug

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379117A (en) 1961-12-05 1983-04-05 W. R. Grace & Co. Method for preparing a film of vinylidene chloride polymer
US3337665A (en) 1964-10-12 1967-08-22 Union Carbide Corp Method for the production of thermoplastic film
US3625214A (en) 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
DE2114065C2 (en) 1971-03-23 1982-08-19 Heinrich Pannenbecker Process for the production of foils from thermoplastics with adhesive properties
US3920805A (en) 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US3926188A (en) 1974-11-14 1975-12-16 Alza Corp Laminated drug dispenser
CA1076480A (en) * 1975-04-28 1980-04-29 John S. Kent Inert core implant pellet
US4191741A (en) * 1978-09-22 1980-03-04 Eli Lilly And Company Removable drug implant
IT1177349B (en) 1984-11-28 1987-08-26 Prandi G & C Off Mec CIRCULAR COEXTRUSION HEAD OF MULTIPLE LAYERS OF THERMOPLASTIC MATERIALS
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US5601835A (en) 1987-04-29 1997-02-11 Massachusetts Institute Of Technology Polymeric device for controlled drug delivery to the CNS
US4883666A (en) 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US5114719A (en) 1987-04-29 1992-05-19 Sabel Bernhard A Extended drug delivery of small, water-soluble molecules
US5063018A (en) 1990-06-04 1991-11-05 Cordis Corporation Extrusion method
US5683719A (en) 1990-11-22 1997-11-04 British Technology Group Limited Controlled release compositions
DE69616551T2 (en) 1995-07-04 2002-05-29 Akzo Nobel Nv RING-SHAPED DEVICE
US5733565A (en) * 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant
DE19608423A1 (en) 1996-03-05 1997-09-11 Merck Patent Gmbh Phased drug delivery implants
US20030059471A1 (en) 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
TW586944B (en) 1998-05-29 2004-05-11 Sumitomo Pharma Controlled release agent having a multi-layer structure
US6117441A (en) * 1998-07-02 2000-09-12 The Population Council, Inc. Silicone core long term androgen delivery implant
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6585765B1 (en) 2000-06-29 2003-07-01 Advanced Cardiovascular Systems, Inc. Implantable device having substances impregnated therein and a method of impregnating the same
US6506437B1 (en) 2000-10-17 2003-01-14 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device having depots formed in a surface thereof
US6713081B2 (en) * 2001-03-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Ocular therapeutic agent delivery devices and methods for making and using such devices
US6780424B2 (en) 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
ES2663873T3 (en) * 2001-10-29 2018-04-17 Massachusetts Institute Of Technology Pharmaceutical form with zero order release profile manufactured by three-dimensional printing
PT2561860T (en) 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of buprenorphine
ES2359977T3 (en) * 2003-03-31 2011-05-30 Titan Pharmaceuticals, Inc. IMPLANTABLE POLYMER DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST.
WO2004110400A2 (en) 2003-05-30 2004-12-23 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of nalmefene
US8313763B2 (en) 2004-10-04 2012-11-20 Tolmar Therapeutics, Inc. Sustained delivery formulations of rapamycin compounds
KR100511618B1 (en) 2005-01-17 2005-08-31 이경범 Multi-layer coating of drug release controllable coronary stent and method for manufacturing the same
DE102005034453A1 (en) * 2005-07-23 2007-01-25 Voith Patent Gmbh Method for producing a paper machine screen
US20090022806A1 (en) 2006-12-22 2009-01-22 Mousa Shaker A Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists and formulations and uses thereof
WO2007139744A2 (en) 2006-05-23 2007-12-06 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of buprenorphine with minimal initial burst
WO2008062008A1 (en) 2006-11-22 2008-05-29 N.V. Organon Delivery system for a non-steroidal non-ionized hydrophilic drug
TW200930343A (en) 2007-09-21 2009-07-16 Organon Nv Drug delivery system
AU2009270849B2 (en) * 2008-07-17 2013-11-21 Micell Technologies, Inc. Drug delivery medical device
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
UY32492A (en) * 2009-03-17 2010-10-29 Organon Nv ZOOTECH DRUG SUPPLY DEVICE.
CA2792179C (en) 2010-03-16 2019-04-02 Titan Pharmaceuticals, Inc. Heterogeneous implantable devices for drug delivery

Also Published As

Publication number Publication date
US20130202673A1 (en) 2013-08-08
CA2792179C (en) 2019-04-02
JP2015227371A (en) 2015-12-17
SI2547332T1 (en) 2019-01-31
JP2013522314A (en) 2013-06-13
SG184059A1 (en) 2012-10-30
AU2011227289B2 (en) 2016-01-21
EP2547332A1 (en) 2013-01-23
ES2699200T3 (en) 2019-02-07
LT2547332T (en) 2018-12-10
JP6022649B2 (en) 2016-11-09
HRP20182014T1 (en) 2019-01-25
CA2792179A1 (en) 2011-09-22
EP2547332B1 (en) 2018-08-29
US10111830B2 (en) 2018-10-30
JP5869551B2 (en) 2016-02-24
PT2547332T (en) 2018-11-27
CY1120964T1 (en) 2019-12-11
US20130189342A1 (en) 2013-07-25
US20130195951A1 (en) 2013-08-01
MX354444B (en) 2018-03-06
RS58011B1 (en) 2019-02-28
AU2011227289A1 (en) 2012-09-27
KR101914119B1 (en) 2018-11-02
MX2012010611A (en) 2013-02-21
KR20130038840A (en) 2013-04-18
PL2547332T3 (en) 2019-07-31
EP2547332A4 (en) 2014-04-16
US20130195950A1 (en) 2013-08-01
US10123971B2 (en) 2018-11-13
WO2011116132A1 (en) 2011-09-22
DK2547332T3 (en) 2018-12-17

Similar Documents

Publication Publication Date Title
HRP20182014T1 (en) Heterogeneous implantable devices for drug delivery
EP2398531A4 (en) Implantable drug delivery devices
GB2479953B (en) Drug delivery device
HK1198139A1 (en) Drug delivery medical device
HK1179542A1 (en) Drug delivery device
EP2593039A4 (en) Drug delivery medical device
SG10201700716VA (en) Drug delivery device
ZA201301155B (en) Ophthalmic drug delivery
ZA201201751B (en) Implantable device for controlled drug delivery
EP2544741A4 (en) Medicament delivery device
EP2533834A4 (en) Medicament delivery device
HUE051942T2 (en) Implantable drug delivery devices for genitourinary sites
ZA201302588B (en) Medicament delivery device
EP2640448A4 (en) Medicament delivery device
PL3023120T3 (en) Devices for transdermal drug delivery
EP2640449A4 (en) Medicament delivery device
PL2353632T3 (en) Medical device for local drug delivery
IL227352A0 (en) Ocular drug delivery system
ZA201208185B (en) Intravaginall drug delivery device
EP2560711A4 (en) Medicament delivery device
EP2626055A4 (en) Drug delivery device
GB201018750D0 (en) Drug delivery system