AR004781A1 - Derivados de 2-(sulfanil substituido)-3,5-dihidro-imidazol-4-ona y su uso en la preparacionn de medicamentos. - Google Patents

Derivados de 2-(sulfanil substituido)-3,5-dihidro-imidazol-4-ona y su uso en la preparacionn de medicamentos.

Info

Publication number
AR004781A1
AR004781A1 ARP960105365A ARP960105365A AR004781A1 AR 004781 A1 AR004781 A1 AR 004781A1 AR P960105365 A ARP960105365 A AR P960105365A AR P960105365 A ARP960105365 A AR P960105365A AR 004781 A1 AR004781 A1 AR 004781A1
Authority
AR
Argentina
Prior art keywords
carbon atoms
medicines
dihydro
derivatives
preparation
Prior art date
Application number
ARP960105365A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/563,841 external-priority patent/US5599829A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of AR004781A1 publication Critical patent/AR004781A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivados de 2-(sulfanil sustituido)-3,5-dihidro-imidazol-4-ona de fórmula (I), en donde R es fenilo o fenilo opcionalmente sustituido con uno o másgrupos seleccionados de halógeno, alquilo de 1 a 6 átomos de carbono, perfluoralquilo de 1a 6 átomos de carbono, alcoxi de 1 a 6 átomos de carbono,perfluoralcoxi de 1 a 6 átomos de carbono, hidroxi, alcanoiloxi de 2 a 6 átomos de carbono, aroiloxi de 7 a 11 átomos de carbono o arilaalcanoiloxi de 8 a 16átomos de carbono; R3 es alquilo de1 a 6 átomos de carbono, arilo de 6 a 10 átomos de carbono o arilalquilo de 7 a 12 átomos de carbono; o una salfarmacéuticamente aceptable del mismo, que se usan para incrementar los niveles sanguíneo de HDL y su uso en la preparación de medicamentos.
ARP960105365A 1995-11-28 1996-11-27 Derivados de 2-(sulfanil substituido)-3,5-dihidro-imidazol-4-ona y su uso en la preparacionn de medicamentos. AR004781A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US765395P 1995-11-28 1995-11-28
US08/563,841 US5599829A (en) 1995-11-28 1995-11-28 2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives for increasing HDL cholesterol levels

Publications (1)

Publication Number Publication Date
AR004781A1 true AR004781A1 (es) 1999-03-10

Family

ID=26677246

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105365A AR004781A1 (es) 1995-11-28 1996-11-27 Derivados de 2-(sulfanil substituido)-3,5-dihidro-imidazol-4-ona y su uso en la preparacionn de medicamentos.

Country Status (6)

Country Link
EP (1) EP0876354A1 (es)
JP (1) JP2000514401A (es)
AR (1) AR004781A1 (es)
AU (1) AU1063497A (es)
CA (1) CA2238812A1 (es)
WO (1) WO1997019931A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1426046A4 (en) 2001-09-14 2005-11-02 Shionogi & Co NEW USE OF TRICYCLIC COMPOUNDS
ATE502298T1 (de) 2003-12-19 2011-04-15 Univ California Verfahren und materialien zur beurteilung von prostatakrebstherapien
US7718684B2 (en) 2004-02-24 2010-05-18 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
ES2593379T3 (es) 2006-03-27 2016-12-09 The Regents Of The University Of California Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
JP5350217B2 (ja) 2006-03-29 2013-11-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ジアリールチオヒダントイン化合物
UY31432A1 (es) 2007-10-26 2009-05-29 Compuestos de diarilhidantoina
US9108944B2 (en) 2010-02-16 2015-08-18 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
CN104661658A (zh) 2012-09-26 2015-05-27 阿拉贡药品公司 用于治疗非转移性去势抵抗性前列腺癌的抗雄激素
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
CN111479560A (zh) 2017-10-16 2020-07-31 阿拉贡药品公司 用于治疗非转移性去势难治性前列腺癌的抗雄激素

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
WO1994020460A1 (en) * 1993-03-11 1994-09-15 Smithkline Beecham Corporation Chemical compounds
US5554607A (en) * 1995-11-28 1996-09-10 American Home Products Corporation Use of 2-thioxo-imidazolin-4-one derivatives in the treatment of atherosclerosis

Also Published As

Publication number Publication date
AU1063497A (en) 1997-06-19
WO1997019931A1 (en) 1997-06-05
CA2238812A1 (en) 1997-06-05
JP2000514401A (ja) 2000-10-31
EP0876354A1 (en) 1998-11-11

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