AP419A - Pharmaceutical aerosol formulation comprising beclomethasone diproprionate monohydrate. - Google Patents
Pharmaceutical aerosol formulation comprising beclomethasone diproprionate monohydrate. Download PDFInfo
- Publication number
- AP419A AP419A APAP/P/1993/000484A AP9300484A AP419A AP 419 A AP419 A AP 419A AP 9300484 A AP9300484 A AP 9300484A AP 419 A AP419 A AP 419A
- Authority
- AP
- ARIPO
- Prior art keywords
- formulation
- monohydrate
- propellant
- weight
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929202519A GB9202519D0 (en) | 1992-02-06 | 1992-02-06 | Medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9300484A0 AP9300484A0 (en) | 1993-04-30 |
| AP419A true AP419A (en) | 1995-10-24 |
Family
ID=10709929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1993/000484A AP419A (en) | 1992-02-06 | 1993-02-05 | Pharmaceutical aerosol formulation comprising beclomethasone diproprionate monohydrate. |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US5695744A (ru) |
| EP (1) | EP0625046B1 (ru) |
| JP (1) | JP3675474B2 (ru) |
| CN (1) | CN1048394C (ru) |
| AP (1) | AP419A (ru) |
| AT (1) | ATE157875T1 (ru) |
| AU (1) | AU667074B2 (ru) |
| BG (1) | BG61862B1 (ru) |
| CA (1) | CA2128688A1 (ru) |
| CZ (1) | CZ281942B6 (ru) |
| DE (1) | DE69313825T2 (ru) |
| DK (1) | DK0625046T3 (ru) |
| ES (1) | ES2106360T3 (ru) |
| GB (1) | GB9202519D0 (ru) |
| GE (1) | GEP19991820B (ru) |
| GR (1) | GR3025363T3 (ru) |
| HK (1) | HK1009588A1 (ru) |
| HU (2) | HUT68986A (ru) |
| IL (1) | IL104628A (ru) |
| IS (1) | IS1622B (ru) |
| MX (1) | MX9300620A (ru) |
| MY (1) | MY108748A (ru) |
| NO (1) | NO306453B1 (ru) |
| NZ (1) | NZ246889A (ru) |
| OA (1) | OA10091A (ru) |
| RO (1) | RO118173B1 (ru) |
| RU (1) | RU2120285C1 (ru) |
| SK (1) | SK279291B6 (ru) |
| TW (1) | TW299234B (ru) |
| WO (1) | WO1993015741A1 (ru) |
| ZA (1) | ZA93800B (ru) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5919435A (en) * | 1990-11-09 | 1999-07-06 | Glaxo Group Limited | Aerosol formulation containing a particulate medicament |
| CA2125666C (en) | 1991-12-12 | 2002-07-16 | Rachel Ann Akehurst | Medicaments |
| IL104068A (en) | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant |
| US7105152B1 (en) | 1991-12-18 | 2006-09-12 | 3M Innovative Properties Company | Suspension aerosol formulations |
| US7101534B1 (en) | 1991-12-18 | 2006-09-05 | 3M Innovative Properties Company | Suspension aerosol formulations |
| ATE204743T1 (de) * | 1991-12-18 | 2001-09-15 | Minnesota Mining & Mfg | Aerosolzusammensetzungen für arzneimittelsuspensionen |
| US5833950A (en) * | 1992-07-31 | 1998-11-10 | Glaxo Group Limited | Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate |
| GB9404945D0 (en) | 1994-03-15 | 1994-04-27 | Glaxo Group Ltd | Pharmaceutical composition |
| MX9704550A (es) * | 1994-12-22 | 1997-10-31 | Astra Ab | Formulaciones de medicamentos en aerosol. |
| US6013245A (en) * | 1995-01-26 | 2000-01-11 | Glaxo Group Limited | Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant |
| US5874481A (en) * | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
| DK0835098T3 (da) | 1995-06-27 | 2002-10-07 | Boehringer Ingelheim Pharma | Stabilt lægemiddelpræparat til frembringlese af drivgasfrie aerosoler |
| ES2175676T3 (es) * | 1997-01-14 | 2002-11-16 | Lohmann Therapie Syst Lts | Sistema terapeutico expansible de retencion gastrica con liberacion controlada de principio activo en el tracto gastrointestinal. |
| SK122199A3 (en) * | 1997-03-18 | 2000-12-11 | Basf Ag | Methods and compositions for modulating responsiveness to corticosteroids |
| US6054487A (en) * | 1997-03-18 | 2000-04-25 | Basf Aktiengesellschaft | Methods and compositions for modulating responsiveness to corticosteroids |
| US6129905A (en) * | 1997-04-21 | 2000-10-10 | Aeropharm Technology, Inc. | Aerosol formulations containing a sugar as a dispersant |
| US5891420A (en) * | 1997-04-21 | 1999-04-06 | Aeropharm Technology Limited | Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation |
| US5891419A (en) * | 1997-04-21 | 1999-04-06 | Aeropharm Technology Limited | Environmentally safe flunisolide aerosol formulations for oral inhalation |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6598603B1 (en) * | 1997-12-31 | 2003-07-29 | Astra Aktiebolag | Method for treating respiratory diseases |
| US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
| TWI243687B (en) * | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
| US6458338B1 (en) | 1998-09-22 | 2002-10-01 | Aeropharm Technology Incorporated | Amino acid stabilized medicinal aerosol formulations |
| US6136294C1 (en) * | 1998-09-22 | 2002-09-24 | Aeropharm Technology Inc | Amino acid stabilized medical aerosol formulation |
| IT1303692B1 (it) * | 1998-11-03 | 2001-02-23 | Chiesi Farma Spa | Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione. |
| US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
| US6261539B1 (en) * | 1998-12-10 | 2001-07-17 | Akwete Adjei | Medicinal aerosol formulation |
| US7074388B2 (en) * | 1998-12-10 | 2006-07-11 | Kos Life Science, Inc. | Water stabilized medicinal aerosol formulation |
| US6540983B1 (en) | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
| US6540982B1 (en) * | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
| US6565833B1 (en) | 2000-05-01 | 2003-05-20 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
| US6447750B1 (en) | 2000-05-01 | 2002-09-10 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
| US6548049B1 (en) | 2000-05-01 | 2003-04-15 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| EP1280520B2 (en) | 2000-05-10 | 2018-03-21 | Novartis AG | Phospholipid-based powders for drug delivery |
| WO2002007672A2 (en) * | 2000-07-19 | 2002-01-31 | Aeropharm Technology, Inc. | A medicinal aerosol formulation |
| CA2417973A1 (en) * | 2000-08-04 | 2002-02-14 | Longwood Pharmaceutical Research, Inc. | Formulations of mometasone and a bronchodilator for pulmonary administration |
| US6455028B1 (en) | 2001-04-23 | 2002-09-24 | Pharmascience | Ipratropium formulation for pulmonary inhalation |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| TWI324518B (en) | 2001-12-19 | 2010-05-11 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| EP1415647A1 (en) * | 2002-10-23 | 2004-05-06 | CHIESI FARMACEUTICI S.p.A. | "Long-acting beta-2 agonists ultrafine formulations" |
| AU2007231727B2 (en) * | 2002-09-03 | 2010-12-16 | Kos Life Sciences, Inc. | Water stabilized medicinal aerosol formulation |
| MXPA05009920A (es) * | 2003-03-20 | 2005-11-04 | Boehringer Ingelheim Pharma | Formulacion para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores. |
| US20040191176A1 (en) * | 2003-03-28 | 2004-09-30 | Kaplan Leonard W | Formulations for treatment of pulmonary disorders |
| CA2536876A1 (en) * | 2003-08-29 | 2005-03-17 | Glaxo Group Limited | Pharmaceutical metered dose inhaler and methods relating thereto |
| AR041873A1 (es) * | 2003-10-30 | 2005-06-01 | Pablo Cassara Srl Lab | Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante |
| US20050238632A1 (en) * | 2004-04-23 | 2005-10-27 | Alburty David S | Propellant formulations |
| JP5209963B2 (ja) † | 2004-07-02 | 2013-06-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 噴霧剤としてｔｇ２２７ｅａ又はｔｇ１３４ａを含有するエアロゾル懸濁製剤 |
| US9084799B2 (en) | 2005-02-11 | 2015-07-21 | Pulmagen Therapeutics (Synergy) Limited | Inhaled combination therapy |
| DK1845994T3 (da) | 2005-02-11 | 2009-05-04 | Argenta Discovery Ltd | Kombination af methylxanthinforbindelser og steroider til at behandle kroniske luftvejssygdomme |
| DE102006017320A1 (de) | 2006-04-11 | 2007-10-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel |
| US20070286814A1 (en) * | 2006-06-12 | 2007-12-13 | Medispray Laboratories Pvt. Ltd. | Stable aerosol pharmaceutical formulations |
| WO2008097664A1 (en) | 2007-02-11 | 2008-08-14 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
| RU2504402C1 (ru) * | 2012-11-20 | 2014-01-20 | Шолекс Девелопмент Гмбх | Ингаляционный состав в форме аэрозоля для лечения бронхиальной астмы и хронической обструктивной болезни легких |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2076422A (en) * | 1980-05-19 | 1981-12-02 | Orion Yhtymae Oy | Aerosols containing anti-inflammatory steroids |
| GB2107715A (en) * | 1981-10-19 | 1983-05-05 | Glaxo Group Ltd | Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR890000664B1 (ko) * | 1981-10-19 | 1989-03-22 | 바리 안소니 뉴우샘 | 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법 |
| GB8432063D0 (en) * | 1984-12-19 | 1985-01-30 | Riker Laboratories Inc | Physically modified steroids |
| JP2769925B2 (ja) * | 1990-10-18 | 1998-06-25 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | ベクロメタゾン１７，２１ジプロピオネートを含んで成るエアロゾル製剤 |
-
1992
- 1992-02-06 GB GB929202519A patent/GB9202519D0/en active Pending
-
1993
- 1993-02-02 EP EP93917355A patent/EP0625046B1/en not_active Expired - Lifetime
- 1993-02-02 DE DE69313825T patent/DE69313825T2/de not_active Expired - Lifetime
- 1993-02-02 RO RO94-01278A patent/RO118173B1/ro unknown
- 1993-02-02 NZ NZ246889A patent/NZ246889A/en unknown
- 1993-02-02 DK DK93917355.5T patent/DK0625046T3/da active
- 1993-02-02 AU AU34525/93A patent/AU667074B2/en not_active Ceased
- 1993-02-02 CA CA002128688A patent/CA2128688A1/en not_active Abandoned
- 1993-02-02 AT AT93917355T patent/ATE157875T1/de active
- 1993-02-02 ES ES93917355T patent/ES2106360T3/es not_active Expired - Lifetime
- 1993-02-02 HU HU9402301A patent/HUT68986A/hu unknown
- 1993-02-02 US US08/256,294 patent/US5695744A/en not_active Expired - Lifetime
- 1993-02-02 RU RU94040361A patent/RU2120285C1/ru active
- 1993-02-02 JP JP51372993A patent/JP3675474B2/ja not_active Expired - Fee Related
- 1993-02-02 CZ CZ941846A patent/CZ281942B6/cs not_active IP Right Cessation
- 1993-02-02 SK SK924-94A patent/SK279291B6/sk unknown
- 1993-02-02 WO PCT/EP1993/000223 patent/WO1993015741A1/en active IP Right Grant
- 1993-02-04 MX MX9300620A patent/MX9300620A/es active IP Right Grant
- 1993-02-05 IS IS3974A patent/IS1622B/is unknown
- 1993-02-05 ZA ZA93800A patent/ZA93800B/xx unknown
- 1993-02-05 IL IL10462893A patent/IL104628A/en not_active IP Right Cessation
- 1993-02-05 TW TW082100772A patent/TW299234B/zh active
- 1993-02-05 MY MYPI93000190A patent/MY108748A/en unknown
- 1993-02-05 AP APAP/P/1993/000484A patent/AP419A/en active
- 1993-02-05 CN CN93102529A patent/CN1048394C/zh not_active Expired - Fee Related
- 1993-02-06 GE GEAP19932600A patent/GEP19991820B/en unknown
-
1994
- 1994-07-08 BG BG98897A patent/BG61862B1/bg unknown
- 1994-08-04 OA OA60548A patent/OA10091A/en unknown
- 1994-08-05 NO NO942923A patent/NO306453B1/no unknown
-
1995
- 1995-06-02 US US08/458,241 patent/US5688782A/en not_active Expired - Lifetime
- 1995-06-09 HU HU95P/P00177P patent/HU211696A9/hu unknown
-
1997
- 1997-11-12 GR GR970403005T patent/GR3025363T3/el unknown
-
1998
- 1998-09-01 HK HK98110346A patent/HK1009588A1/xx not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2076422A (en) * | 1980-05-19 | 1981-12-02 | Orion Yhtymae Oy | Aerosols containing anti-inflammatory steroids |
| GB2107715A (en) * | 1981-10-19 | 1983-05-05 | Glaxo Group Ltd | Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it |
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