AP2936A - Long term treatment of HIV-infection with TMC278 - Google Patents

Long term treatment of HIV-infection with TMC278

Info

Publication number
AP2936A
AP2936A AP2008004535A AP2008004535A AP2936A AP 2936 A AP2936 A AP 2936A AP 2008004535 A AP2008004535 A AP 2008004535A AP 2008004535 A AP2008004535 A AP 2008004535A AP 2936 A AP2936 A AP 2936A
Authority
AP
ARIPO
Prior art keywords
tmc278
hiv
infection
long term
term treatment
Prior art date
Application number
AP2008004535A
Other languages
English (en)
Other versions
AP2008004535A0 (en
Inventor
Lieven Elvire Colette Baert
Guenter Kraus
Gerben Albert Eleutherius Van T Klooster
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36446113&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2936(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of AP2008004535A0 publication Critical patent/AP2008004535A0/xx
Application granted granted Critical
Publication of AP2936A publication Critical patent/AP2936A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2008004535A 2006-01-20 2007-01-19 Long term treatment of HIV-infection with TMC278 AP2936A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06100677 2006-01-20
PCT/EP2007/050516 WO2007082922A2 (en) 2006-01-20 2007-01-19 Long term treatment of hiv- infection with tcm278

Publications (2)

Publication Number Publication Date
AP2008004535A0 AP2008004535A0 (en) 2008-08-31
AP2936A true AP2936A (en) 2014-07-31

Family

ID=36446113

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004535A AP2936A (en) 2006-01-20 2007-01-19 Long term treatment of HIV-infection with TMC278

Country Status (27)

Country Link
US (4) US10953009B2 (hr)
EP (1) EP1981506B3 (hr)
JP (2) JP5754005B2 (hr)
KR (2) KR101501475B1 (hr)
CN (2) CN103877091A (hr)
AP (1) AP2936A (hr)
AR (1) AR059097A1 (hr)
AU (1) AU2007206901B2 (hr)
BR (1) BRPI0707179A2 (hr)
CA (1) CA2636436C (hr)
CY (1) CY1114089T1 (hr)
DK (1) DK1981506T6 (hr)
EA (1) EA014914B1 (hr)
ES (1) ES2414982T7 (hr)
HR (1) HRP20130544T4 (hr)
IL (1) IL192132A (hr)
ME (1) ME01617B (hr)
MY (1) MY150717A (hr)
NZ (1) NZ569347A (hr)
PL (1) PL1981506T6 (hr)
PT (1) PT1981506E (hr)
RS (1) RS52821B2 (hr)
SG (1) SG170073A1 (hr)
SI (1) SI1981506T1 (hr)
TW (1) TWI458483B (hr)
UA (1) UA96436C2 (hr)
WO (1) WO2007082922A2 (hr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
TW201414495A (zh) * 2005-04-04 2014-04-16 Tibotec Pharm Ltd Hiv-感染之預防
PT1981506E (pt) 2006-01-20 2013-06-25 Janssen R & D Ireland Tratamento a longo prazo da infeção pelo vih com tmc278
CN101478950B (zh) * 2006-06-23 2013-02-06 泰博特克药品有限公司 Tmc278的水性悬浮液
AU2014200819B2 (en) * 2006-06-23 2016-05-26 Janssen Sciences Ireland Uc Aqueous suspensions of TMC278
AU2016219555B2 (en) * 2006-06-23 2017-08-10 Janssen Sciences Ireland Uc Aqueous suspensions of TMC278
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
RU2546529C2 (ru) * 2008-12-24 2015-04-10 Тиботек Фармасьютикалз Имплантируемые устройства для лечения вич
AU2010299959B2 (en) * 2009-09-22 2016-07-21 Tibotec Pharmaceuticals Treatment and prevention of HIV infection
AU2010338425B2 (en) 2009-12-21 2015-07-23 Janssen Sciences Ireland Uc Degradable removable implant for the sustained release of an active compound
LT3494972T (lt) * 2010-01-27 2024-03-12 Viiv Healthcare Company Dolutegraviro ir lamivudino kompozicija živ infekcijai gydyti
TWI577377B (zh) * 2010-09-16 2017-04-11 Viiv醫療保健公司 醫藥組合物
US9266824B2 (en) 2014-01-13 2016-02-23 Warsaw Orthopedic, Inc. Methods and compositions for making an amino acid triisocyanate
CA3005313C (en) * 2015-11-16 2024-01-09 Evonik Rohm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
US20190163877A1 (en) * 2017-11-27 2019-05-30 International Business Machines Corporation Decision support for effective long-term drug therapy
WO2022079739A1 (en) 2020-10-14 2022-04-21 Cipla Limited Fixed dose compositions of cabotegravir and rilpivirine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005021001A1 (en) * 2003-09-03 2005-03-10 Tibotec Pharmaceuticals Ltd. Combinations of a pyrimidine containing nnrti with rt inhibitors

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US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
JPH06316524A (ja) 1992-09-11 1994-11-15 Naoyuki Inoue 抗エイズウイルス剤
US6045829A (en) 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
US6258932B1 (en) 1999-08-09 2001-07-10 Tripep Ab Peptides that block viral infectivity and methods of use thereof
AU7984200A (en) 1999-09-21 2001-04-24 Skyepharma Canada Inc. Surface modified particulate compositions of biologically active substances
BR0109602A (pt) 2000-03-30 2004-06-29 Bristol Myers Squibb Co Glóbulos de liberação controlada contendo estavudina
US20040115268A1 (en) 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
US7638522B2 (en) 2001-08-13 2009-12-29 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
JP2005511629A (ja) 2001-11-20 2005-04-28 アドバンスト インハレーション リサーチ,インコーポレイテッド 持続作用生成物送達用組成物
US6568805B1 (en) * 2001-11-26 2003-05-27 Dan L. Dietz Trust Magnetic buckle for eyeglasses
AU2003210659A1 (en) * 2002-01-24 2003-09-02 Sangstat Medical Corporation Combination therapy for treatment of hiv infection
JP2006508134A (ja) 2002-11-08 2006-03-09 グラクソ グループ リミテッド 医薬組成物
WO2004046309A2 (en) 2002-11-18 2004-06-03 Phoenix Pharmacologics, Inc. Methods for inhibiting viral replication in vivo
BRPI0407329A (pt) 2003-02-07 2006-01-10 Janssen Pharmaceutica Nv Derivados de pirimidina para a prevenção de infecção de hiv
KR20050101221A (ko) 2003-02-21 2005-10-20 트리펩 아베 Hiv 복제의 억제를 위한 글리신아미드 유도체
AU2005279158C1 (en) * 2004-09-02 2010-12-16 Janssen Pharmaceutica N.V. Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl] amino]benzonitrile
BRPI0514871A (pt) * 2004-09-02 2008-06-24 Janssen Pharmaceutica Nv cloridrato de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]-2-pirimidi nil]amino] benzonitrila
CN101106972A (zh) 2004-11-16 2008-01-16 伊兰制药国际有限公司 注射用纳米微粒奥氮平制剂
TW201414495A (zh) 2005-04-04 2014-04-16 Tibotec Pharm Ltd Hiv-感染之預防
PT1981506E (pt) 2006-01-20 2013-06-25 Janssen R & D Ireland Tratamento a longo prazo da infeção pelo vih com tmc278
CN101478950B (zh) 2006-06-23 2013-02-06 泰博特克药品有限公司 Tmc278的水性悬浮液
CA2693044C (en) 2007-07-12 2017-03-14 Tibotec Pharmaceuticals Crystalline form of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2 pyrimidinyl]amino]benzonitrile

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005021001A1 (en) * 2003-09-03 2005-03-10 Tibotec Pharmaceuticals Ltd. Combinations of a pyrimidine containing nnrti with rt inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SUSMAN E.: "RETROVIRUSES AND OPPORTUNISTIC INFECTIONS", IDRUGS, CURRENT DRUGS LTD., GB, vol. 8, no. 4, 2005, pages 299-302, XP008051947, ISSN: 1369-7056, page 300, column 2, paragraph 2 *

Also Published As

Publication number Publication date
WO2007082922A3 (en) 2007-09-20
SG170073A1 (en) 2011-04-29
JP2013100338A (ja) 2013-05-23
US10953009B2 (en) 2021-03-23
HRP20130544T1 (en) 2013-07-31
DK1981506T3 (da) 2013-06-24
UA96436C2 (ru) 2011-11-10
EP1981506A2 (en) 2008-10-22
KR101562943B1 (ko) 2015-10-23
AU2007206901B2 (en) 2013-01-31
KR101501475B1 (ko) 2015-03-19
TWI458483B (zh) 2014-11-01
ES2414982T7 (es) 2021-11-05
WO2007082922A2 (en) 2007-07-26
NZ569347A (en) 2011-07-29
MY150717A (en) 2014-02-28
EP1981506B1 (en) 2013-03-27
US20110275654A1 (en) 2011-11-10
AP2008004535A0 (en) 2008-08-31
ES2414982T3 (es) 2013-07-23
CN103877091A (zh) 2014-06-25
SI1981506T1 (sl) 2013-08-30
BRPI0707179A2 (pt) 2011-04-26
TW200806295A (en) 2008-02-01
USRE50189E1 (en) 2024-10-29
JP2009526758A (ja) 2009-07-23
CA2636436C (en) 2014-04-01
PT1981506E (pt) 2013-06-25
EA014914B1 (ru) 2011-02-28
HRP20130544T4 (hr) 2021-08-20
JP5836983B2 (ja) 2015-12-24
HK1125828A1 (en) 2009-08-21
ME01617B (me) 2014-09-20
PL1981506T3 (pl) 2013-08-30
AR059097A1 (es) 2008-03-12
CA2636436A1 (en) 2007-07-26
IL192132A0 (en) 2009-08-03
AU2007206901A1 (en) 2007-07-26
DK1981506T6 (da) 2021-06-14
US20240226099A1 (en) 2024-07-11
CN101370504A (zh) 2009-02-18
KR20080085194A (ko) 2008-09-23
RS52821B (sr) 2013-10-31
RS52821B2 (sr) 2021-07-30
EA200870183A1 (ru) 2009-12-30
PL1981506T6 (pl) 2021-07-12
WO2007082922A8 (en) 2008-01-03
JP5754005B2 (ja) 2015-07-22
US20210177843A1 (en) 2021-06-17
EP1981506B3 (en) 2021-06-09
CY1114089T1 (el) 2016-07-27
KR20140141699A (ko) 2014-12-10
IL192132A (en) 2014-05-28

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