AP2860A - Carbazole compounds and therapeutic uses of the compounds - Google Patents
Carbazole compounds and therapeutic uses of the compoundsInfo
- Publication number
- AP2860A AP2860A AP2011005637A AP2011005637A AP2860A AP 2860 A AP2860 A AP 2860A AP 2011005637 A AP2011005637 A AP 2011005637A AP 2011005637 A AP2011005637 A AP 2011005637A AP 2860 A AP2860 A AP 2860A
- Authority
- AP
- ARIPO
- Prior art keywords
- compounds
- therapeutic uses
- carbazole
- carbazole compounds
- therapeutic
- Prior art date
Links
- 125000000609 carbazolyl group Chemical class C1(=CC=CC=2C3=CC=CC=C3NC12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C4/00—Foldable, collapsible or dismountable chairs
- A47C4/02—Dismountable chairs
- A47C4/028—Upholstered chairs, e.g. metal, plastic or wooden chairs
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C13/00—Convertible chairs, stools or benches
- A47C13/005—Modular seating
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C15/00—Other seating furniture
- A47C15/002—Corner seating furniture, e.g. corner sofas
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C17/00—Sofas; Couches; Beds
- A47C17/04—Seating furniture, e.g. sofas, couches, settees, or the like, with movable parts changeable to beds; Chair beds
- A47C17/045—Seating furniture having loose or by fabric hinge connected cushions changeable to beds
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C31/00—Details or accessories for chairs, beds, or the like, not provided for in other groups of this subclass, e.g. upholstery fasteners, mattress protectors, stretching devices for mattress nets
- A47C31/003—Magnets
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C7/00—Parts, details, or accessories of chairs or stools
- A47C7/02—Seat parts
- A47C7/18—Seat parts having foamed material included in cushioning part
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47C—CHAIRS; SOFAS; BEDS
- A47C7/00—Parts, details, or accessories of chairs or stools
- A47C7/02—Seat parts
- A47C7/18—Seat parts having foamed material included in cushioning part
- A47C7/20—Seat parts having foamed material included in cushioning part with reinforcement in the foam layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B1/00—Devices for securing together, or preventing relative movement between, constructional elements or machine parts
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B12/00—Jointing of furniture or the like, e.g. hidden from exterior
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B2200/00—Constructional details of connections not covered for in other groups of this subclass
- F16B2200/81—Use of a material of the hooks-and-loops type
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B2200/00—Constructional details of connections not covered for in other groups of this subclass
- F16B2200/83—Use of a magnetic material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T403/00—Joints and connections
- Y10T403/71—Rod side to plate or side
- Y10T403/7164—One rod held between bight and other rod extending through aperture in leg of connector
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T403/00—Joints and connections
- Y10T403/71—Rod side to plate or side
- Y10T403/7176—Resilient clip
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Mechanical Engineering (AREA)
- Nursing (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10291308P | 2008-10-06 | 2008-10-06 | |
PCT/US2009/059558 WO2010042445A1 (en) | 2008-10-06 | 2009-10-05 | Carbazole compounds and therapeutic uses of the compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2011005637A0 AP2011005637A0 (en) | 2011-04-30 |
AP2860A true AP2860A (en) | 2014-02-28 |
Family
ID=41503680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2011005637A AP2860A (en) | 2008-10-06 | 2009-10-05 | Carbazole compounds and therapeutic uses of the compounds |
Country Status (27)
Country | Link |
---|---|
US (5) | US8765738B2 (it) |
EP (1) | EP2356093B1 (it) |
JP (1) | JP5694172B2 (it) |
KR (1) | KR101586112B1 (it) |
CN (1) | CN102203063B (it) |
AP (1) | AP2860A (it) |
AU (1) | AU2009302546B2 (it) |
BR (1) | BRPI0920876A2 (it) |
CA (1) | CA2736097C (it) |
CU (1) | CU24087B1 (it) |
CY (1) | CY1113924T1 (it) |
DK (1) | DK2356093T3 (it) |
ES (1) | ES2402395T3 (it) |
GE (1) | GEP20146131B (it) |
HR (1) | HRP20130313T1 (it) |
IL (1) | IL211430A0 (it) |
MX (1) | MX2011003416A (it) |
NZ (1) | NZ591516A (it) |
PL (1) | PL2356093T3 (it) |
PT (1) | PT2356093E (it) |
RS (1) | RS52702B (it) |
RU (1) | RU2497807C2 (it) |
SI (1) | SI2356093T1 (it) |
SM (1) | SMT201300042B (it) |
UA (1) | UA107652C2 (it) |
WO (1) | WO2010042445A1 (it) |
ZA (1) | ZA201101513B (it) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA107652C2 (en) * | 2008-10-06 | 2015-02-10 | Incuron Llc | Carbazole compounds and therapeutic uses of the compounds |
JP5831068B2 (ja) * | 2011-09-13 | 2015-12-09 | コニカミノルタ株式会社 | 縮合複素環化合物の製造方法 |
WO2013072915A1 (en) * | 2011-11-15 | 2013-05-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Tricyclic compounds, compositions comprising them and uses thereof |
EA028630B1 (ru) * | 2012-03-27 | 2017-12-29 | ИНКУРОН ЭлЭлСи | Способ предотвращения вызванного канцерогеном рака с применением кураксина-137 |
CN104203915B (zh) | 2012-04-25 | 2017-03-08 | 霍夫曼-拉罗奇有限公司 | (3,4‑二氯‑苯基)‑((s)‑3‑丙基‑吡咯烷‑3‑基)‑甲酮盐酸盐和制造方法 |
JP6377054B2 (ja) | 2012-05-11 | 2018-08-22 | リセット セラピューティークス, インコーポレイテッド | クリプトクロム調節薬としてのカルバゾール含有スルホンアミド |
WO2014124454A1 (en) | 2013-02-11 | 2014-08-14 | Katerina Gurova | Use of facilitates chromatin transcription complex (fact) in cancer |
WO2014207688A1 (en) * | 2013-06-26 | 2014-12-31 | Universidade Do Porto | Tryptophanol-derived oxazoloisoindolinones: small-molecule p53 activators |
WO2015020553A1 (en) * | 2013-08-07 | 2015-02-12 | Obschestvo S Ogranichennoy Otvetstvennost'yu "Panacela Labs" | Carbazole compounds and methods of using same |
WO2015020556A1 (ru) * | 2013-08-08 | 2015-02-12 | Общество С Ограниченной Ответственностью "Панацела Лабс" | Соединения ксеномицина с противогрибковыми свойствами |
WO2015050471A1 (en) * | 2013-10-02 | 2015-04-09 | Obschestvo S Ogranichennoy Otvetstvennost'yu "Panacela Labs" | Carbazole compounds and methods of using same |
WO2015050472A1 (en) * | 2013-10-02 | 2015-04-09 | Obschestvo S Ogranichennoy Otvetstvennost'yu "Panacela Labs" | Fused indole compounds and methods of using same |
WO2015089187A1 (en) * | 2013-12-10 | 2015-06-18 | Incuron, Llc | Methods of modulating various biomarkers with curaxins |
US10434086B2 (en) | 2014-04-06 | 2019-10-08 | Incuron, Inc. | Combination therapies with curaxins |
TWI690521B (zh) | 2014-04-07 | 2020-04-11 | 美商同步製藥公司 | 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類 |
CN103936654B (zh) * | 2014-04-08 | 2016-05-18 | 南京林业大学 | 一类脱氢枞酸吲哚衍生物的用途 |
CN111533734A (zh) * | 2014-07-04 | 2020-08-14 | 默克专利股份有限公司 | 具有抗寄生虫活性的氮杂环庚烷基衍生物和包含它们的药物组合物 |
US10632102B2 (en) | 2015-06-15 | 2020-04-28 | Raziel Therapeutics Ltd | Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof |
CN105272903B (zh) * | 2015-11-17 | 2018-07-10 | 江苏师范大学 | 系列含氟咔唑类化合物及其制备方法和应用 |
WO2019062872A1 (zh) * | 2017-09-30 | 2019-04-04 | 成都中创蜀洋生物科技有限公司 | 氘代咔唑类化合物 |
CN109528712B (zh) * | 2019-01-24 | 2020-11-17 | 江南大学 | 9-甲基-3,6-二乙酰基咔唑用于治疗或预防肿瘤疾病的用途 |
JP2023503769A (ja) * | 2019-09-15 | 2023-02-01 | ラジエル セラピューティクス エルティーディー. | 固形腫瘍の処置のための組成物 |
WO2023220558A1 (en) * | 2022-05-09 | 2023-11-16 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Combination of curaxins and immune checkpoint inhibitors for treating cancer |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2715680A1 (de) * | 1977-04-07 | 1978-10-12 | Henkel Kgaa | Haarfaerbemittel |
AU2003272175A1 (en) * | 2002-10-21 | 2004-05-04 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
EP1462105A1 (en) * | 2003-03-28 | 2004-09-29 | Procorde GmbH | Activation specific inhibitors of NF-kB and method of treating inflammatory processes in cardio-vascular diseases |
US7169802B2 (en) * | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
WO2006012419A2 (en) * | 2004-07-20 | 2006-02-02 | Cleveland Clinic Foundation | Inhibition of nf-kb |
JP2009001495A (ja) * | 2005-10-13 | 2009-01-08 | Taisho Pharmaceutical Co Ltd | 2−アリール−ベンゾイミダゾール−5−カルボキサミド誘導体 |
ES2390135T3 (es) * | 2005-11-22 | 2012-11-06 | Merck Sharp & Dohme Corp. | Compuestos tricíclicos útiles como inhibidores de quinasas |
WO2008008155A2 (en) | 2006-06-20 | 2008-01-17 | The Trustees Of The University Of Pennsylvania | Small molecule modulators of p53 family signaling |
RU2315594C1 (ru) * | 2006-09-01 | 2008-01-27 | Всеволод Иванович Киселев | Антиэстрогенное и антипролиферативное средство для лечения и профилактики заболеваний женской репродуктивной системы |
UA107652C2 (en) * | 2008-10-06 | 2015-02-10 | Incuron Llc | Carbazole compounds and therapeutic uses of the compounds |
EA028630B1 (ru) * | 2012-03-27 | 2017-12-29 | ИНКУРОН ЭлЭлСи | Способ предотвращения вызванного канцерогеном рака с применением кураксина-137 |
-
2009
- 2009-05-10 UA UAA201105704A patent/UA107652C2/ru unknown
- 2009-10-05 NZ NZ591516A patent/NZ591516A/en not_active IP Right Cessation
- 2009-10-05 CN CN200980140333.1A patent/CN102203063B/zh active Active
- 2009-10-05 DK DK09793304.8T patent/DK2356093T3/da active
- 2009-10-05 WO PCT/US2009/059558 patent/WO2010042445A1/en active Application Filing
- 2009-10-05 AU AU2009302546A patent/AU2009302546B2/en active Active
- 2009-10-05 EP EP09793304A patent/EP2356093B1/en active Active
- 2009-10-05 AP AP2011005637A patent/AP2860A/xx active
- 2009-10-05 MX MX2011003416A patent/MX2011003416A/es active IP Right Grant
- 2009-10-05 CU CU2011000078A patent/CU24087B1/es active IP Right Grant
- 2009-10-05 GE GEAP200912213A patent/GEP20146131B/en unknown
- 2009-10-05 CA CA2736097A patent/CA2736097C/en not_active Expired - Fee Related
- 2009-10-05 ES ES09793304T patent/ES2402395T3/es active Active
- 2009-10-05 US US13/121,051 patent/US8765738B2/en active Active
- 2009-10-05 PT PT97933048T patent/PT2356093E/pt unknown
- 2009-10-05 BR BRPI0920876-3A patent/BRPI0920876A2/pt not_active IP Right Cessation
- 2009-10-05 KR KR1020117009438A patent/KR101586112B1/ko active IP Right Grant
- 2009-10-05 SI SI200930552T patent/SI2356093T1/sl unknown
- 2009-10-05 PL PL09793304T patent/PL2356093T3/pl unknown
- 2009-10-05 JP JP2011530291A patent/JP5694172B2/ja not_active Expired - Fee Related
- 2009-10-05 RS RS20130125A patent/RS52702B/en unknown
- 2009-10-05 RU RU2011108932/04A patent/RU2497807C2/ru active IP Right Revival
-
2011
- 2011-02-25 ZA ZA2011/01513A patent/ZA201101513B/en unknown
- 2011-02-27 IL IL211430A patent/IL211430A0/en active IP Right Grant
-
2013
- 2013-04-05 HR HRP20130313AT patent/HRP20130313T1/hr unknown
- 2013-04-08 CY CY20131100288T patent/CY1113924T1/el unknown
- 2013-04-12 SM SM201300042T patent/SMT201300042B/it unknown
-
2014
- 2014-04-01 US US14/231,841 patent/US9108916B2/en active Active
-
2015
- 2015-06-04 US US14/731,202 patent/US9566265B2/en active Active
-
2016
- 2016-12-21 US US15/386,020 patent/US10137109B2/en active Active
-
2018
- 2018-10-12 US US16/159,089 patent/US20190082845A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2860A (en) | Carbazole compounds and therapeutic uses of the compounds | |
HK1211889A1 (en) | Therapeutic use of diaminophenothiazines | |
GB0803018D0 (en) | Therapeutic compounds and their use | |
GB0719803D0 (en) | Therapeutic compounds and their use | |
GB0804685D0 (en) | Therapeutic compounds and their use | |
EP2320907A4 (en) | THERAPEUTIC COMPOUNDS | |
EP2300011A4 (en) | METHODS AND THERAPEUTIC COMPOUNDS | |
GB0719644D0 (en) | Therapeutic compounds and their use | |
EP2068864A4 (en) | THERAPEUTIC USES OF UROLITHINS | |
EP2268285A4 (en) | THERAPEUTIC COMPOUNDS | |
GB0807609D0 (en) | Therapeutic compounds and their use | |
GB0921075D0 (en) | Novel combination of the therapeutic agents | |
GB0724251D0 (en) | Therapeutic compounds and their use | |
GB0722680D0 (en) | Therapeutic compounds and their use | |
EP2268281A4 (en) | THIENOPYRROLES AND PYRROLOTHIAZOLES AS NEW THERAPEUTIC AGENTS | |
GB0804755D0 (en) | Therapeutic compounds | |
GB0817208D0 (en) | Therapeutic apsap compounds and their use | |
IL205137A0 (en) | 5-cyanothienopyridines for the treatment of tumours | |
HRP20130395T1 (en) | Treatment of melanoma | |
GB0715790D0 (en) | Drug combination for the treatment of sialorrhoea | |
GB0812913D0 (en) | Therapeutic compounds and their use | |
EP2231163A4 (en) | COMPOUNDS AND THEIR THERAPEUTIC USE | |
EP2157089A4 (en) | THERAPEUTIC USES OF IMIDAZOL-5-CARBOXYLIC ACID DERIVATIVES | |
GB0723100D0 (en) | Treatment of HFnEF | |
GB0802128D0 (en) | Therapeutic compounds and their use |