AP197A - Pharmaceutical formulations for treatment of virus infections of the skin containing penciclovir. - Google Patents

Pharmaceutical formulations for treatment of virus infections of the skin containing penciclovir. Download PDF

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Publication number
AP197A
AP197A APAP/P/1991/000236A AP9100236A AP197A AP 197 A AP197 A AP 197A AP 9100236 A AP9100236 A AP 9100236A AP 197 A AP197 A AP 197A
Authority
AP
ARIPO
Prior art keywords
penciclovir
pharmaceutical formulation
propylene glycol
formulation according
water
Prior art date
Application number
APAP/P/1991/000236A
Other languages
English (en)
Other versions
AP9000236A0 (en
Inventor
Hazel-Ann Griffiths
Alan John Goodall
Joshua Oduro-Yeboah
Original Assignee
Novartis Int Pharmaceutical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Int Pharmaceutical Ltd filed Critical Novartis Int Pharmaceutical Ltd
Publication of AP9000236A0 publication Critical patent/AP9000236A0/xx
Application granted granted Critical
Publication of AP197A publication Critical patent/AP197A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
APAP/P/1991/000236A 1990-01-26 1991-01-25 Pharmaceutical formulations for treatment of virus infections of the skin containing penciclovir. AP197A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909001886A GB9001886D0 (en) 1990-01-26 1990-01-26 Pharmaceutical formulation

Publications (2)

Publication Number Publication Date
AP9000236A0 AP9000236A0 (en) 1991-01-31
AP197A true AP197A (en) 1992-06-30

Family

ID=10669997

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000236A AP197A (en) 1990-01-26 1991-01-25 Pharmaceutical formulations for treatment of virus infections of the skin containing penciclovir.

Country Status (29)

Country Link
EP (1) EP0511991B1 (zh)
JP (1) JP2545317B2 (zh)
KR (1) KR0170414B1 (zh)
CN (1) CN1056058C (zh)
AP (1) AP197A (zh)
AT (1) ATE142880T1 (zh)
AU (1) AU643975B2 (zh)
CA (1) CA2074503C (zh)
CY (2) CY1984A (zh)
DE (1) DE69122229T2 (zh)
DK (1) DK0511991T3 (zh)
ES (1) ES2092559T3 (zh)
FI (1) FI101600B (zh)
GB (1) GB9001886D0 (zh)
GR (1) GR3021385T3 (zh)
HK (1) HK218996A (zh)
HU (1) HU215842B (zh)
IE (1) IE910249A1 (zh)
IL (1) IL97008A (zh)
LU (1) LU90110I2 (zh)
MA (1) MA22051A1 (zh)
MY (1) MY110074A (zh)
PL (1) PL166678B1 (zh)
PT (1) PT96563B (zh)
SA (1) SA91110341B1 (zh)
SG (1) SG49144A1 (zh)
TW (1) TW307687B (zh)
WO (1) WO1991011187A1 (zh)
ZA (1) ZA91525B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114939D0 (en) * 1991-07-11 1991-08-28 Smithkline Beecham Plc Pharmaceutical formulation
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
GB9601544D0 (en) 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals
US7223387B2 (en) 1998-11-18 2007-05-29 Medivir Ab Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester
WO2017029298A1 (en) 2015-08-17 2017-02-23 Sanovel Ilac Sanayi Ve Ticaret A.S. A topical antiviral composition
US11364198B2 (en) 2018-04-05 2022-06-21 Bausch Health Ireland Limited Polymeric emulsion delivery systems

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044543A1 (en) * 1980-07-18 1982-01-27 The Wellcome Foundation Limited Topical formulations of 9-(2-hydroxyethoxymethyl) guanine
EP0141927A2 (en) * 1983-08-18 1985-05-22 Beecham Group Plc Antiviral guanine derivatives
EP0146516A2 (en) * 1983-12-20 1985-06-26 Astra Läkemedel Aktiebolag Derivatives of Guanine, process for their preparation and a pharmaceutical preparation
EP0152316A1 (en) * 1984-01-26 1985-08-21 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
KR830005852A (ko) * 1980-07-18 1983-09-14 미첼 페터 잭슨 피부와 점막의 비루스 감염치료에 적합한 국소치료제의 제조방법
EP0095813A3 (en) * 1982-06-01 1985-05-08 THE PROCTER & GAMBLE COMPANY Penetrating topical pharmaceutical compositions containing 9-(2-hydroxyethoxymethyl) guanine
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044543A1 (en) * 1980-07-18 1982-01-27 The Wellcome Foundation Limited Topical formulations of 9-(2-hydroxyethoxymethyl) guanine
EP0141927A2 (en) * 1983-08-18 1985-05-22 Beecham Group Plc Antiviral guanine derivatives
EP0146516A2 (en) * 1983-12-20 1985-06-26 Astra Läkemedel Aktiebolag Derivatives of Guanine, process for their preparation and a pharmaceutical preparation
EP0152316A1 (en) * 1984-01-26 1985-08-21 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions

Also Published As

Publication number Publication date
HU215842B (hu) 2001-02-28
SA91110341B1 (ar) 2004-05-25
KR920703060A (ko) 1992-12-17
FI923371A0 (fi) 1992-07-24
IL97008A0 (en) 1992-03-29
CY1999020I2 (en) 2009-11-04
SG49144A1 (en) 1998-05-18
CN1056058C (zh) 2000-09-06
DE69122229T2 (de) 1997-03-06
MA22051A1 (fr) 1991-10-01
ES2092559T3 (es) 1996-12-01
IE910249A1 (en) 1991-07-31
AU643975B2 (en) 1993-12-02
PT96563B (pt) 1998-07-31
AP9000236A0 (en) 1991-01-31
LU90110I2 (fr) 1997-09-25
DK0511991T3 (da) 1996-11-11
FI923371A (fi) 1992-07-24
EP0511991A1 (en) 1992-11-11
FI101600B1 (fi) 1998-07-31
CA2074503A1 (en) 1991-07-27
PL166678B1 (pl) 1995-06-30
JPH05503695A (ja) 1993-06-17
ATE142880T1 (de) 1996-10-15
CA2074503C (en) 1999-12-14
EP0511991B1 (en) 1996-09-18
FI101600B (fi) 1998-07-31
PT96563A (pt) 1991-10-15
HU9202431D0 (en) 1992-10-28
CN1053547A (zh) 1991-08-07
AU7155891A (en) 1991-08-21
DE69122229D1 (de) 1996-10-24
GB9001886D0 (en) 1990-03-28
WO1991011187A1 (en) 1991-08-08
KR0170414B1 (ko) 1999-02-18
TW307687B (zh) 1997-06-11
MY110074A (en) 1997-12-31
CY1984A (en) 1997-09-05
HUT62472A (en) 1993-05-28
HK218996A (en) 1997-01-03
ZA91525B (en) 1992-02-26
GR3021385T3 (en) 1997-01-31
IL97008A (en) 1995-05-26
JP2545317B2 (ja) 1996-10-16

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