JPH08301708A - Industrial germicidal composition - Google Patents

Abstract

PURPOSE: To obtain a composition, capable of manifesting excellent exterminating and proliferation suppressing effects on bacteria and molds and good in preservation stability by dissolving a germicide containing cyanoacetamides combined with methylenebisthiocyanate in a specific compound. CONSTITUTION: This industrial germicidal composition is obtained by dissolving an industrial germicidal composition containing (A) a cyanoacetamide compound of the formula (X is a halogen; Y is H or a halogen; R<1> and R<2> are each H or a lower alkyl) and (B) methylenebisthiocyanate in propylene carbonate. The blending weight ratio of the ingredients (A) to (B) is (10:1) to (1:10). 2,2- Dibromo-3-nitrilopropionamide is especially preferred as the ingredient (A) due to its excellence in bactericidal activities. The composition can advantageously be preserved and transported especially under high-temperature conditions. The composition can be used in various water systems especially in the pulp industrial field, e.g. white water in papermaking processes or various water systems such as circulating and cooling water in various industrial fields and further water-based coating materials, coating liquids for paper, latexes, etc., prepared by using industrial water.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a novel industrial fungicide composition, and more particularly, it has excellent bactericidal and fungicidal killing effect and reproduction suppressing effect, and also has good storage stability. The present invention relates to an industrial bactericidal composition suitable for use in various fields including water systems in the pulp and paper industry.

[0002]

2. Description of the Related Art Conventionally, various water systems in the pulp and paper industry, such as white water in the papermaking process and circulating cooling water in various industries, as well as water-based paints and papers prepared using industrial water. In the fields of coating liquids, latexes, polymer emulsions, printing pastes, adhesives, metalworking oils such as cutting oils, leather and wood, molds harmful to them, microorganisms such as bacteria easily propagate, This causes the deterioration of productivity and quality. Especially in the water system in the pulp and paper industry, slime is generated by the multiplication of bacteria, filamentous fungi, and yeasts, and the channel in which the pulp slurry flows, especially the rough wall surface where the slurry contacts, chests, flow boxes, transport pipes, etc. Slime is deposited and formed in a place where the flow velocity of the pipe slurry becomes small and stagnates.

The slime is often detached, which causes paper scraps and contamination of paper pipe products, and causes various obstacles due to the growth of microorganisms.

The occurrence of such a trouble becomes a serious problem particularly when a high speed machine is used, which causes a remarkable decrease in productivity and an economic loss.

Further, for example, the proliferation of microorganisms in a circulating water system for cooling, such as a metalworking oil, impairs cooling performance and emulsification properties, and also produces a bad odor, which worsens the working environment and is a phenomenon unfavorable to public health. cause.

In addition, other problems caused by the proliferation of harmful microorganisms are caused in industrial products such as water-based paints, coating liquids for paper, latexes, polymer emulsions, printing pastes, adhesives, and metal working oils such as cutting oils. Also seen.

By the way, as agents for suppressing or controlling the generation of harmful microorganisms in the water system or the industrial products, for example, organometallic compounds, organochlorine compounds, organosulfur compounds and quaternary ammonium salts have hitherto been used. , Etc. have been used, but these compounds are toxic to the human body, give off a bad odor or an offensive odor, and cause undesirable phenomena such as foaming. In addition, these pesticide-containing water systems, when they are thrown into general rivers or the sea, have an adverse effect on seafood and cause environmental problems.

As a substance which can avoid such a problem, for example, a bactericidal agent is known in which a cyanoacetamide compound and methylenebisthiocyanate are dissolved in a solvent such as ethylene glycol or polyethylene glycol (Japanese Patent Laid-Open Publication No. Sho. 57-114502). However, it is extremely difficult to produce a pure methylenebisthiocyanate that is free of impurities, and part of the methylenebisthiocyanate is altered during storage, so methylenebisthiocyanate must contain a slight amount of impurities. ing. Therefore, when this methylenebisthiocyanate is dissolved in a solvent such as ethylene glycol or polyethylene glycol in combination with a cyanoacetamide compound, some of the impurities contained in the methylenebisthiocyanate accelerate the decomposition of the cyanoacetamide compound, This bactericide has poor storage stability, and the concentration of the cyanoacetamide compound is unavoidable as time passes. Therefore, when the drug is stored for a long period of time, particularly when the drug is stored under high temperature conditions such as in the summer, there are drawbacks such as deterioration of the drug due to deterioration of the bactericidal effect and discoloration of the drug.

[0009]

DISCLOSURE OF THE INVENTION The present invention overcomes the above-mentioned drawbacks found in bactericides in which a cyanoacetamide compound and methylenebisthiocyanate are combined, and contains a cyanoacetamide compound and methylenebisthiocyanate, and is excellent in bacteria and The purpose of the present invention is to provide an industrial fungicide composition which has a fungicidal killing effect and a growth inhibitory effect and has good storage stability.

[0010]

Means for Solving the Problems The present inventors have conducted extensive studies to improve the storage stability of an industrial fungicide composition containing a cyanoacetamide compound and methylenebisthiocyanate, and as a result, It was found that the object can be achieved by dissolving methylenebisthiocyanate in propylene carbonate, and the present invention has been completed based on this finding.

That is, the present invention provides (A) the general formula

Embedded image (In the formula, X is a halogen atom, Y is a hydrogen atom or a halogen atom, and R ¹ and R ² are each a hydrogen atom or a lower alkyl group, and they may be the same or different. And a cyanoacetamide compound represented by the formula (4) and (B) methylenebisthiocyanate are dissolved in propylene carbonate.

In the industrial germicidal composition of the present invention,
As the component (A), the cyanoacetamide compound represented by the general formula (I) is used. This general formula (I)
In the above, X is a halogen atom, Y is a hydrogen atom or a halogen atom, and the halogen atom of X and the halogen atom of Y are preferably a chlorine atom and a bromine atom, respectively. R ¹ and R ² are each a hydrogen atom or a lower alkyl group, and examples of the lower alkyl group include a methyl group, an ethyl group, an n-propyl group and an isopropyl group. R ¹ and R ² may be the same or different.

Examples of the cyanoacetamide compound as the component (C) include 2-chloro-3-nitrilopropionamide, N-methyl-2-chloro-3-nitrilopropionamide, N, N-dimethyl-2-chloro- 3-Nitrilopropionamide, 2,2-dichloro-3-nitrilopropionamide, N-methyl-2,2-dichloro-3-nitrilopropionamide, N, N-dimethyl-
2,2-dichloro-3-nitrilopropionamide, 2
-Bromo-3-nitrilopropionamide, N-methyl-2-bromo-3-nitrilopropionamide, N, N
-Dimethyl-2-bromo-3-nitrilopropionamide, 2,2-dibromo-3-nitrilopropionamide, N-methyl-2,2-dibromo-3-nitrilopropionamide, N, N-dimethyl-2,2 -Dibromo-
3-Nitrilopropionamide and the like can be mentioned. These may be used singly or in combination of two or more, and among them, 2,2-dibromo-3-nitrilopropionamide is particularly preferable because it has excellent bactericidal properties.

In the fungicide composition of the present invention, (A)
The mixing ratio of the component and the component (B) is preferably 10: 1 to 1:10 by weight, more preferably 10: 1 to 1: 5, because an excellent synergistic effect can be obtained. . When the amount of the component (A) is too small, the bactericidal activity against bacteria decreases. On the other hand, if the amount of component (B) is too small, the bactericidal activity against mold is reduced, and the inhibitory activity against bacterial growth is reduced.

The bactericidal composition of the present invention is of a solvent solution type in which propylene carbonate is used as a solvent and the above-mentioned components (A) and (B) are blended therein. Propylene carbonate is preferably used alone, and when it is mixed with other solvent, the storage stability decreases.

The amount of the disinfectant composition to be added at the time of use varies depending on the concentration of microorganisms, but generally in the case of water systems in the fields such as the pulp and paper industry, the total of the components (A) and (B). 1 to 100 ppm based on the amount, 10 to 500 pp in the case of water-based paint, glue, leather, etc.
m, and a good bactericidal effect can be obtained in this range.

If desired, water or a surfactant may be added to the bactericidal composition of the present invention as long as the object of the present invention is not impaired.

[0018]

INDUSTRIAL APPLICABILITY The industrial bactericidal composition of the present invention is a mixture of a cyanoacetamide compound and methylenebisthiocyanate in propylene carbonate, and its deterioration is remarkably suppressed and its stability is extremely high. Therefore,
Its storage and transportation, especially storage and transportation under high temperature conditions, can be advantageously performed.

The industrial bactericidal composition of the present invention is excellent in sterilization and fungicidal effects as well as in bacterial and fungal growth inhibitory effects, and is particularly useful for water systems in the pulp and paper industry, such as white water and various kinds of paper making processes. In addition to various water systems such as circulating cooling water in the industrial field, water-based paints prepared using industrial water, paper coating liquids, latexes, polymer emulsions, printing pastes, adhesives, metals such as cutting oils. It is preferably used for processing oils, leather and other fields.

[0020]

EXAMPLES The present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.

Examples 1 to 6 and Comparative Examples 1 to 5 After preparing industrial fungicidal compositions having the compositions shown in Tables 1 and 2, each sample was stored in a thermostatic chamber at 55 ° C. Take a portion of the sample and use liquid chromatography to
The residual concentration of 2-dibromo-3-nitrilopropionamide was measured. The results are shown in Table 3. The residual rate is expressed by the following equation. Residual rate (%) = (b / a) × 100 a: initial concentration of 2,2-dibromo-3-nitrilopropionamide b: daily concentration of 2,2-dibromo-3-nitrilopropionamide

[0022]

[Table 1]

[0023]

[Table 2]

[0024]

[Table 3]

Claims (1)

[Claims] 1. (A) General formula: (In the formula, X is a halogen atom, Y is a hydrogen atom or a halogen atom, and R ¹ and R ² are each a hydrogen atom or a lower alkyl group, and they may be the same or different. ) A bactericidal composition for industrial use, comprising a cyanoacetamide compound represented by the formula (4) and (B) methylenebisthiocyanate dissolved in propylene carbonate.