CN112891748A - Magnetic shock therapeutic instrument - Google Patents

Magnetic shock therapeutic instrument Download PDF

Info

Publication number
CN112891748A
CN112891748A CN202110081621.7A CN202110081621A CN112891748A CN 112891748 A CN112891748 A CN 112891748A CN 202110081621 A CN202110081621 A CN 202110081621A CN 112891748 A CN112891748 A CN 112891748A
Authority
CN
China
Prior art keywords
charging module
module
electronic switch
electrically connected
power factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110081621.7A
Other languages
Chinese (zh)
Other versions
CN112891748B (en
Inventor
葛康
廖兆恒
徐竹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Yiruide Medical Equipment Co Ltd
Original Assignee
Wuhan Yiruide Medical Equipment Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Yiruide Medical Equipment Co Ltd filed Critical Wuhan Yiruide Medical Equipment Co Ltd
Priority to CN202110081621.7A priority Critical patent/CN112891748B/en
Publication of CN112891748A publication Critical patent/CN112891748A/en
Application granted granted Critical
Publication of CN112891748B publication Critical patent/CN112891748B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Magnetic Treatment Devices (AREA)

Abstract

The invention provides a magnetic shock therapeutic apparatus, which comprises a computer, a processor, an acquisition module, a man-machine interaction module, a control signal generation module, a cooling device, a charging and discharging system and an electronic switch group, wherein the processor is connected with the computer; the electronic switch group comprises a first electronic switch and a second electronic switch, the second end of the magnetic stimulation coil is electrically connected with the negative electrode of the first electronic switch and the positive electrode of the second electronic switch, the positive electrode of the first electronic switch and the negative electrode of the second electronic switch are electrically connected with the negative electrode of the energy storage element, and the control electrode of the first electronic switch is in communication connection with the control signal generation module.

Description

Magnetic shock therapeutic instrument
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of transcranial magnetic stimulation, in particular to a magnetic shock therapeutic apparatus.
[ background of the invention ]
Magnetic shock is a magnetic stimulation technique derived from electroshock therapy with fewer side effects and better treatment effect. Electric shock (ECT) and Magnetic Shock (MST) are essentially therapeutic methods for electrical stimulation to cause Seizure.
Since the convulsion induced by the electric shock is a necessary condition for achieving the therapeutic effect, the higher the stimulation intensity is, the better the therapeutic effect is, but the side effect of the high-intensity electric shock is increased. Although electroshock has a wide range of clinical therapeutic effects, common side effects include headache, dizziness, nausea, confusion, disorientation, arrhythmia, respiratory disturbance, and the like. Some people even suffer severe (even permanent) impairment of memory and cognitive function.
The electric shock and the magnetic shock have the same action mechanism and common property of tic treatment, and when the electric shock causes tic attack, the deep part of the brain can be affected due to the high impedance of the scalp and the skull and the large stimulation current is needed, so that certain memory and cognitive function damage is caused. The induced current of the magnetic shock only acts on the cerebral cortex part, can not only cause the seizure like the electric shock, but also obtain the treatment effect of the electric shock and has few side effects of the electric shock. Therefore, magnetic shock is expected to replace traditional electric shock as a new method for treating mental diseases.
Transcranial Magnetic Stimulation (TMS) technology, born in 1985, can replace electroshock in many ways, but the output intensity of conventional TMS devices rarely causes seizure. TMS is defined as noninvasive and painless transcranial stimulation, convulsion is a side effect and a contraindication of use, and TMS with low stimulation strength is generally considered to not achieve the treatment effect of electroshock.
Magnetic field stimulation of TMS has limitations on the stimulation site, with stimulation depths of typically 2.5cm, which theoretically can induce convulsions with high frequency, high intensity, long duration streaming stimulation if beyond the safe stimulation range of conventional TMS. Dhuna et al in 1991 for the first time with a frequency of 16Hz (repeat-
Actual transport magnetic stimulation) rTMS continuous stimulation for 10s triggered a seizure in one subject, thus demonstrating for the first time that magnetic stimulation could trigger a tic, provoking a magnetic shock therapy.
MST is also called magnetic twitch therapy, and can more accurately induce induction current in the surface space of the cerebral cortex by using stronger output voltage than TMS, and the current is parallel to the cerebral cortex and is difficult to reach the deep layer of the brain; the stimulation current of the electric shock is perpendicular to the cerebral cortex, and the memory and cognitive functions can be influenced by changing the deep hippocampal structure of the brain. The hippocampus is located in the temporal lobe of the primate and is the key to memory formation. It receives sensory information and projects broadly to other brain regions such as the limbic system, the prefrontal cortex, the amygdala, the thalamus, the striatum, and the cortical union. Different connection paths are full of information for learning memory and emotional colors.
MST can also induce tic attack by continuously stimulating cerebral cortex for several seconds with high-frequency strong pulse magnetic field, and modern magnetic shock instrument can complete one treatment with 100Hz stimulation and 2 Tesla (T) stimulation for less than 10 s. Transient tic is widely considered by the medical community to treat various neuropsychiatric diseases, and the treatment effect is related to the degree of tic.
The MST technology achieves the therapeutic effect of the electric shock by using the TMS means, and simultaneously keeps the characteristics of noninvasive, limited and focused stimulation of the TMS. MST requires anesthesia and must induce tics, TMS does not require anesthesia and cannot induce tics, which is an essential difference of 2 techniques. Current experiments show that MST has no side effect of cognitive and memory disorder of electric shock, and can enhance cognitive and memory functions. TMS treats the old patients without side effects on the aspect of cardiovascular, the old people have insufficient TMS stimulation strength and unsatisfactory stimulation curative effect due to aging, degeneration and atrophy of cranial nerves and increased distance between cortical nerves and scalp, and the strong stimulation of MST can also compensate the insufficient TMS stimulation amount. The development of MST relates to the development of equipment, the clinical trial research of animals and human beings, the feasibility research of MST on depression patients, the neuroelectrophysiological characteristic response, the influence on memory and cognition, the treatment effect, the safety evaluation and the like.
From 1995 to 1998, the narcotized animals were also unable to induce seizure using the strongest commercially available TMS device (25 Hz). While exceeding the rTMS safety range can elicit epileptic-like convulsions in humans. To date, tic seizures have not been elicited in rodent trials. In 1998, Lisanby et al in the United states, after failure of rats to MST, analyzed that the reason for this may be that the stimulation coil is too large and the rat head is too small, and that the local magnetic flux density is not sufficient to create induced currents that induce local twitches in the rat head. The experiment was successful instead in primate macaques, and then a batch of scientific domestic monkeys were used to study the effects of MST on comparative electroshock on brain neurophysiology, neuroanatomy and neurocognitive function. In 2000, Lisanby et al, for the first time in Switzerland succeeded in inducing twitch attacks on human MST under anesthesia, and demonstrated for the first time the effectiveness and safety of MST in the treatment of depression.
In 2003, Lisanby first conducted a clinical trial of electroshock in comparison with MST in the United states, and then conducted an open experimental study of the antidepressant efficacy of MST in 2 research centers. Their early clinical studies demonstrated MST feasibility, antidepressant efficacy and safety superior to that of electroshock. However, it seems not as therapeutically as for electroconvulsive, the reason for this analysis was that the MST devices at the time were not powerful enough to adequately induce a more powerful seizure.
Because the maximization of the magnetic stimulation intensity and frequency of the existing magnetic stimulation equipment on the market is difficult to satisfy at the same time, the therapeutic effect of the magnetic shock therapy mode is poor.
In view of the above, there is a need to provide a new magnetic shock therapeutic apparatus to overcome the above-mentioned drawbacks.
[ summary of the invention ]
The invention aims to provide a magnetic shock therapeutic apparatus, which utilizes a parallel charging technology, a control generation module receives a command signal with the magnetic stimulation intensity of 100% and the charging frequency of 100Hz within 10ms from a computer to a processor, a first charging module, a second charging module, a third charging module and a fourth charging module simultaneously charge an energy storage element within 10ms, the energy storage element instantly releases 100% of stored energy to a magnetic stimulation coil so that the magnetic field intensity generated by the magnetic stimulation coil reaches 100%, and the magnetic stimulation of 10s is kept in the time of each magnetic stimulation therapy.
In order to achieve the purpose, the invention provides a magnetic shock therapeutic apparatus, which comprises a computer 1, a processor 2, an acquisition module 3, a human-computer interaction module 4, a control signal generation module 5, a cooling device 6, a charging and discharging system 7 and an electronic switch group 8;
the processor 2 is in communication connection with the computer 1, the acquisition module 3, the human-computer interaction module 4 and the control signal generation module 5 are in communication connection with the processor 2, and the cooling device 6 is electrically connected with the control signal generation module 5; the charging and discharging system 7 comprises a first power factor corrector 70, a first charging module 71, a second power factor corrector 72, a second charging module 73, a third power factor corrector 74, a third charging module 75, a fourth power factor corrector 76, a fourth charging module 77, an energy storage element 78 and a magnetic stimulation coil 79, and the control signal generating module 5 is in communication connection with the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77;
the first end of the first power factor corrector 70, the first end of the second power factor corrector 72, the first end of the third power factor corrector 74 and the first end of the fourth power factor corrector 76 are all connected with a three-phase power supply, and the second end of the first power factor corrector 70, the second end of the second power factor corrector 72, the second end of the third power factor corrector 74 and the second end of the fourth power factor corrector 76 are respectively electrically connected with the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77;
the anode of the first charging module 71, the anode of the second charging module 73, the anode of the third charging module 75, and the anode of the fourth charging module 77 are electrically connected to the anode of the energy storage element 78, and the cathode of the first charging module 71, the cathode of the second charging module 73, the cathode of the third charging module 75, and the cathode of the fourth charging module 77 are electrically connected to the cathode of the energy storage element 78;
the first end of the magnetic stimulation coil 79 is electrically connected to the negative electrode of the energy storage element 78, the electronic switch group 8 includes a first electronic switch 81 and a second electronic switch 82, the second end of the magnetic stimulation coil 79 is electrically connected to the negative electrode of the first electronic switch 81 and the positive electrode of the second electronic switch 82, the positive electrode of the first electronic switch 81 and the negative electrode of the second electronic switch 82 are electrically connected to the positive electrode of the energy storage element 78, and the control electrode of the first electronic switch 81 is in communication connection with the control signal generation module 5.
Preferably, the first acquisition module 3 includes an acquisition unit 30, a preamplifier 31, a notch filter 32, a program-controlled amplifier 33, a band-pass filter 34, an a/D converter 35, a first single chip microcomputer 36, a digital signal processor 37, a first isolation transceiver, and a first surge protector; the acquisition unit 30, the preamplifier 31, the notch filter 32, the program-controlled amplifier 33, the band-pass filter 34, the a/D converter 35, the first single chip microcomputer 36 and the digital signal processor 37 are electrically connected in sequence, the first single chip microcomputer 36 is electrically connected with the program-controlled amplifier 33, the first isolation transceiver is electrically connected with the first surge protector, and the first surge protector is electrically connected between the program-controlled amplifier 33 and the first single chip microcomputer 36.
Preferably, the cooling device 6 comprises a second isolation transceiver, a second surge protector, a second single chip microcomputer 60, an isolator 61, a water pump 62, an air pump 63, a water tank 64, a flow sensor 65 and a temperature sensor 66; transceiver, second surge protector, second singlechip 60, isolator 61 are kept apart to the second in proper order electric connection, water pump 62 and air pump 63 all with isolator 61 electric connection, just water pump 62 and air pump 63 all with water tank 64 is connected, cooling device 6's water tank 64 with magnetic stimulation coil 79 connects, flow sensor 65 and temperature sensor 66 all with second singlechip 60 electric connection, the coolant liquid has been contained in the water tank 64.
Preferably, the cooling device 6 further includes a fan 67, and the fan 67 is disposed adjacent to the water pump 62 and electrically connected to the separator 61.
Preferably, the cooling device 6 further comprises a hydraulic pressure sensor 68 and a liquid level sensor 69; hydraulic pressure sensor 68 with second singlechip 60 electric connection, level sensor 69 with second singlechip 60 electric connection and being located in the water tank 64, hydraulic pressure sensor 68 is used for detecting cooling liquid pressure and uploads the hydraulic information that detects to second singlechip 60, level sensor 68 is used for detecting the liquid level in the water tank and uploads the liquid level information that detects to second singlechip 60, second singlechip 60 passes through liquid level information and hydraulic information processor 2 and uploads to computer 1.
Preferably, the human-computer interaction module 4 includes a key matrix 41, a third single chip microcomputer 42, a sound generator 43, a third isolation transceiver and a third surge protector, the key matrix 41, the sound generator 43, the third isolation transceiver and the third surge protector are all electrically connected to the third single chip microcomputer 42, and the third single chip microcomputer 42 is in communication connection with the processor 2.
Preferably, the human-computer interaction module 4 further includes a breathing lamp 44 and a programmable driver 45, and the programmable driver 45 is electrically connected between the third single-chip microcomputer 42 and the breathing lamp 44.
Preferably, the control signal generating module 5 includes a fourth isolation transceiver, a fourth surge protector, a fourth single chip microcomputer 51 and a photoelectric isolation chip 52, and the fourth isolation transceiver, the fourth surge protector and the photoelectric isolation chip 52 are all electrically connected to the fourth single chip microcomputer 51.
Compared with the prior art, the magnetic shock therapeutic apparatus provided by the invention has the beneficial effects that: utilize parallelly connected charging technique, receive through the computer through the control generation module that the magnetic stimulation intensity that the processor was assigned is 100%, and the instruction signal that charging frequency is 100Hz in 10ms, first module, the second that charges, the third module and the fourth module of charging charge to energy storage component in 10ms simultaneously, energy storage component releases 100% energy storage in the twinkling of an eye and makes on the magnetic stimulation coil magnetic field intensity that magnetic stimulation coil produced reaches 100%, and keeps 10s magnetic stimulation at the time of magnetic stimulation treatment at every turn.
[ description of the drawings ]
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic block diagram of the magnetic shock therapeutic apparatus provided by the present invention.
Fig. 2 is a schematic block diagram of an acquisition module of the magnetic shock therapy apparatus shown in fig. 1.
Fig. 3 is a schematic block diagram of the cooling device of the magnetic shock therapy device shown in fig. 1.
Fig. 4 is a schematic block diagram of a human-computer interaction module of the magnetic shock therapy apparatus shown in fig. 1.
Fig. 5 is a schematic block diagram of a control signal generating module of the magnetic shock therapy apparatus shown in fig. 1.
[ detailed description ] embodiments
In order to make the objects, technical solutions and advantageous effects of the present invention more clearly apparent, the present invention is further described in detail below with reference to the accompanying drawings and the detailed description. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
It will be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for ease of description and simplicity of description, and do not indicate or imply that the referenced devices or elements must be in a particular orientation, constructed and operated in a particular orientation, and are therefore not to be considered limiting.
It is also noted that, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," "disposed," and the like are intended to be inclusive and mean, for example, that they may be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. To those of ordinary skill in the art, the above terms may be specifically defined in the present invention according to the specific circumstances.
Furthermore, the terms "first", "second", and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first", "second", may explicitly or implicitly include one or more of that feature. Further, the meaning of "a plurality" or "a plurality" means two or more unless specifically limited otherwise.
Referring to fig. 1, the present invention provides a magnetic shock therapeutic apparatus, which includes a computer 1, a processor 2, an acquisition module 3, a human-computer interaction module 4, a control signal generation module 5, a cooling device 6, a charging and discharging system 7 and an electronic switch group 8;
the processor 2 is in communication connection with the computer 1, the acquisition module 3, the human-computer interaction module 4 and the control signal generation module 5 are in communication connection with the processor 2, and the cooling device 6 is electrically connected with the control signal generation module 5; the charging and discharging system 7 comprises a first power factor corrector 70, a first charging module 71, a second power factor corrector 72, a second charging module 73, a third power factor corrector 74, a third charging module 75, a fourth power factor corrector 76, a fourth charging module 77, an energy storage element 78 (a capacitor) and a magnetic stimulation coil 79, and the control signal generating module 5 is in communication connection with the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77;
the first end of the first power factor corrector 70, the first end of the second power factor corrector 72, the first end of the third power factor corrector 74 and the first end of the fourth power factor corrector 76 are all connected with an external power supply (mains supply), and the second end of the first power factor corrector 70, the second end of the second power factor corrector 72, the second end of the third power factor corrector 74 and the second end of the fourth power factor corrector 76 are respectively electrically connected with the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77;
the anode of the first charging module 71, the anode of the second charging module 73, the anode of the third charging module 75, and the anode of the fourth charging module 77 are electrically connected to the anode of the energy storage element 78, and the cathode of the first charging module 71, the cathode of the second charging module 73, the cathode of the third charging module 75, and the cathode of the fourth charging module 77 are electrically connected to the cathode of the energy storage element 78;
the first end of the magnetic stimulation coil 79 is electrically connected to the negative electrode of the energy storage element 78, the electronic switch set 8 includes a first electronic switch 81 and a second electronic switch 82, the second end of the magnetic stimulation coil 79 is electrically connected to the negative electrode of the first electronic switch 81 and the positive electrode of the second electronic switch 82, the positive electrode of the first electronic switch 81 and the negative electrode of the second electronic switch 82 are electrically connected to the positive electrode of the energy storage element, and the control electrode of the first electronic switch 81 is in communication connection with the control signal generation module 5.
In the present embodiment, the first electronic switch 81 and the second electronic switch 82 may be any one of a one-way thyristor, a triode thyristor, an IGBT (Insulated Gate Bipolar Transistor) and a MOS Transistor.
Referring to fig. 2 to 5, the processor 2 receives an instruction from the computer 1, and sends a received instruction signal to the acquisition module 3, the human-computer interaction module 4, the control signal generation module 5, and the cooling device 6;
the acquisition modules 3 are all used for acquiring the electromyographic signals of human bodies, generating electrophysiological signals by amplifying, filtering and A/D converting the acquired electromyographic signals of the human bodies and sending the electrophysiological signals to the processor 2, the processor 2 transmits the received electromyographic signals to the computer 1,
the first power factor corrector 70, the second power factor corrector 72, the third power factor corrector 74 and the fourth power factor corrector 76 are all used for converting alternating current of AC220V into direct current of DC360V, the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77 convert the direct current voltage into high-voltage pulse voltage which is continuously output to charge the energy storage element 78, the control signal generating module 5 can receive a single magnetic stimulation command signal of the processor 2 to enable a first electronic switch 81 of the electronic switch group 8 to be turned on, when a second electronic switch 82 is not turned on, the energy storage on the energy storage element 78 is instantaneously released onto the magnetic stimulation coil 79, and the magnetic stimulation coil 79 generates a forward magnetic field; the control signal generating module 5 may further receive a single magnetic stimulation instruction signal from the processor 2, so that the first electronic switch 81 of the electronic switch group 8 is not turned on, and when the second electronic switch 82 is turned on, the stored energy in the magnetic stimulation coil 79 is released to the energy storage element 78 through the second electronic switch 82, and the magnetic stimulation coil 79 generates a reverse magnetic field;
after the signal control production module 5 receives the instruction of adjusting the magnetic stimulation intensity, the interface display intensity percentage of the touch screen of the computer 1 is converted into linear direct current of 0-3.3V and is output to the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77; the cooling device 6 is used for adjusting the temperature of the magnetic stimulation coil 79, and the touch screen of the computer 1 displays the waveform of the magnetic stimulation coil 79;
the control signal generating module 5 can also receive the magnetic stimulation intensity given to the processor 2 by the computer 1 and is 100%, and the instruction signal with the charging frequency of 100Hz in 10ms, the first charging module 71, the second charging module 73, the third charging module 75 and the fourth charging module 77 charge the energy storage element 78 in 10ms at the same time, the energy storage element 78 releases 100% of stored energy to the magnetic stimulation coil 79 instantaneously to enable the magnetic field intensity generated by the magnetic stimulation coil 79 to reach 100%, and the magnetic stimulation of 10s is maintained in the time of each magnetic stimulation treatment.
Further, the first acquisition module 3 includes an acquisition unit 30, a preamplifier 31, a notch filter 32, a program-controlled amplifier 33, a band-pass filter 34, an a/D converter 35, a first single chip microcomputer 36, a digital signal processor 37, a first isolation transceiver, and a first surge protector; the acquisition unit 30, the preamplifier 31, the notch filter 32, the program-controlled amplifier 33, the band-pass filter 34, the a/D converter 35, the first single chip microcomputer 36 and the digital signal processor 37 are electrically connected in sequence, the first single chip microcomputer 36 is electrically connected with the program-controlled amplifier 33, the first isolation transceiver is electrically connected with the first surge protector, the first surge protector is electrically connected between the program-controlled amplifier 33 and the first single chip microcomputer 36, and the first isolation transceiver and the first surge protector are integrated together. It should be noted that the shape and structure of the second acquisition module 4 are the same as those of the first acquisition module 3, and therefore, the description thereof is omitted here.
In the present embodiment, the preamplifier 31 has the functions of isolation and buffering, does not change the signal strength, receives the signal through the input impedance, and transmits the signal in the form of impedance output; the notch filter 32 is used for filtering a 50Hz power frequency signal in the alternating current; the program control amplifier 33 adopts a numerical control programmable gain instrument amplifier of TI company, which can realize the program control gain of 1-8000, the A/D converter 35 adopts a high-speed and high-precision 24-bit analog-to-digital converter AD9028 of ADI company, which is used for converting the signal output by the band-pass filter 34 into a digital signal and then transmitting the digital signal to the digital signal processor 37, the digital signal processor 37 receives the converted signal and then transmits the signal to the computer 1, and the first singlechip 36 has the model of LPC11C 14; the model of the first isolation transceiver is ADM 3058E; the model of the first surge protector is TVS 0701.
When the computer 1 outputs a magnetic stimulation command signal, the acquisition unit 30 of the first acquisition module 3 acquires a waveform after receiving a command signal for acquiring the waveform, the preamplifier 31 receives the command signal for acquiring the waveform and amplifies the command signal for acquiring the waveform, the notch filter 32 receives the amplified command signal for acquiring the waveform and filters the command signal for acquiring the waveform, the program-controlled amplifier 33 receives the filtered command signal for acquiring the waveform and program-controlled amplifies the command signal for acquiring the waveform, the band-pass filter 34 receives the amplified command signal for acquiring the waveform from the program-controlled amplifier 33 and filters the command signal for acquiring the waveform, the a/D converter 35 converts the command signal for acquiring the waveform filtered by the band-pass filter 34 into a digital quantity and transmits the digital quantity to the first single chip microcomputer 36, the first single chip microcomputer 36 sends an instruction to the digital signal processor 37, so that the digital signal processor 37 starts to collect digital quantity received by the first single chip microcomputer 36 and sends the digital quantity to the processor 2, the processor 2 sends the digital quantity to the computer 1, and the first display screen 12 or the second display screen 13 of the computer 1 displays the waveform of the magnetic field.
Further, the cooling device 6 comprises a second isolation transceiver, a second surge protector, a second single chip microcomputer 60, an isolator 61, a water pump 62, an air pump 63, a water tank 64, a flow sensor 65 and a temperature sensor 66; transceiver, second surge protector, second singlechip 60, isolator 61 are kept apart to the second in proper order electric connection, water pump 62 and air pump 63 all with isolator 61 electric connection, just water pump 62 and air pump 63 all with water tank 64 is connected, cooling device 6's water tank 64 with magnetic stimulation coil 79 connects, flow sensor 65 and temperature sensor 66 all with second singlechip 60 electric connection, the coolant liquid has been contained in the water tank 64. In this embodiment, the second isolating transceiver has a model of ADM 3058E; the model of the second surge protector is TVS 0701; the model of the second single chip microcomputer 60 is STM32F103C 6; the isolator 61 IS model IS480P and IS used for isolating interference when the water pump 62 and the air pump 63 rotate.
Further, the cooling device 6 further includes a fan 67, and the fan 67 is disposed adjacent to the water pump 62 and electrically connected to the separator 61.
When the computer 1 outputs a magnetic stimulation instruction signal, an operator gives an instruction to start the fan 67 and the water pump 62 through the computer 1, the second single chip microcomputer 60 of the cooling device 6 receives the instruction and then starts the fan 67 and the water pump 62, the water in the water tank 64 enters the water pump 62 under the action of the water pump 62, then the cooling liquid enters the magnetic stimulation coil 79 to reduce the temperature of the magnetic stimulation coil 79, and flows back to the water tank 64 through the flow sensor 65 and the temperature sensor 66, the flow sensor 65 and the temperature sensor 66 respectively detect the flow and the temperature of the water and upload the detected flow information and temperature information to the second single chip microcomputer 60, then the second single chip microcomputer 60 uploads the flow information and temperature information to the computer 1 through the processor 2 to monitor the circulating flowing state of the cooling liquid, and the flow information and temperature information are displayed by the touch of the computer 1.
When the water pump 62 is started and the flow sensor 65 cannot detect the flow of water, an operator can give an instruction to stop the operation of the water pump 62 and stop the magnetic stimulation of the magnetic stimulation coil 79 through the computer 1; when needing to change magnetic stimulation coil 79 or overhaul, operating personnel can issue the instruction of arranging the coolant liquid through computer 1, at this moment the air pump 62 starts to discharge the remaining coolant liquid in the magnetic stimulation coil 79 back to the water tank 64 in, through the rotational speed of water pump 62, fan 67 and air pump 63 can be adjusted to second singlechip 60.
Further, the cooling device 6 further comprises a hydraulic pressure sensor 68 and a liquid level sensor 69; hydraulic pressure sensor 68 with second singlechip 60 electric connection, level sensor 69 with second singlechip 60 electric connection and being located in the water tank 64, hydraulic pressure sensor 68 is used for detecting cooling liquid pressure and uploads the hydraulic information that detects to second singlechip 60, level sensor 68 is used for detecting the liquid level in the water tank and uploads the liquid level information that detects to second singlechip 60, subsequently second singlechip 60 passes through liquid level information and hydraulic information processor 2 uploads to computer 1, computer 1's touch screen shows liquid level information and hydraulic information.
Further, the human-computer interaction module 4 includes a key matrix 41, a third single chip microcomputer 42, a sound generator 43, a third isolation transceiver and a third surge protector, the key matrix 41, the sound generator 43, the third isolation transceiver and the third surge protector are all electrically connected to the third single chip microcomputer 42, the third single chip microcomputer 42 is in communication connection with the processor 2, and the third isolation transceiver and the third surge protector are integrated together. In this embodiment, the model of the third single chip 42 is LPC11C 14; the model of the third isolation transceiver is ADM3058E, and the model of the third surge protector is TVS 0701.
Further, the human-computer interaction module 4 further includes a breathing lamp 44 and a programmable driver 45, and the programmable driver 45 is electrically connected between the third single chip 42 and the breathing lamp 44. In the present embodiment, the programmable driver 45 has a model ADP8863, and is used for adjusting the light effect of the breathing lamp 44.
When a mouse is used for clicking an interface of a touch screen of the computer 1 or a key of the operation key matrix 41 is used for triggering the magnetic stimulation coil 79 to generate a magnetic field, the computer 1 sends a flicker instruction to the breathing lamp 44 of the human-computer interaction module 4 through the processor 2, and at the moment, an operator can hear a click sound emitted by the sounder 43, so that the brightness of the breathing lamp 44 changes; when the computer 1 issues an instruction for adjusting the magnetic stimulation intensity to the control signal generation module 5 through the processor 2, the stored energy in the energy storage element 78 correspondingly changes the voltage released to the magnetic stimulation coil 79, so as to adjust the magnetic field intensity of the magnetic stimulation coil 79.
Further, the control signal generating module 5 includes a fourth isolation transceiver, a fourth surge protector, a fourth single chip microcomputer 51 and a photoelectric isolation chip 52, the fourth isolation transceiver, the fourth surge protector and the photoelectric isolation chip 52 are all electrically connected to the fourth single chip microcomputer 51, and the fourth isolation transceiver and the fourth surge protector are integrated together. In this embodiment, the model of the fourth single chip microcomputer 51 is STM32F103RF, the model of the fourth isolation transceiver is ADM3058E, the model of the fourth surge protector is TVS0701, and the model of the optoelectronic isolation chip 52 is TLP 521-4.
After receiving the instruction of adjusting the magnetic stimulation intensity, the fourth isolation transceiver of the control signal generation module 5 transmits a high-voltage pulse voltage to the first charging module 71, the second charging module 73, the third charging module 75, and the fourth charging module 77 to charge the energy storage element 78, and the interface display intensity percentage of the touch screen of the computer 1 is converted into a linear 0-3.3V dc quantity and is output to the first charging module 71, the second charging module 73, the third charging module 75, and the fourth charging module 77; the control signal generating module 5 may further receive a single magnetic stimulation instruction signal of the processor 2, so that the first electronic switch 81 of the electronic switch group 8 is turned on, and when the second electronic switch 82 is not turned on, the stored energy on the energy storage element 78 is instantaneously released to the magnetic stimulation coil 79, and the magnetic stimulation coil 79 generates a forward magnetic field; the control signal generating module 5 may further receive a single magnetic stimulation instruction signal from the processor 2, so that the first electronic switch 81 of the electronic switch group 8 is not turned on, and when the second electronic switch 82 is turned on, the stored energy in the magnetic stimulation coil 79 is released to the energy storage element 78 through the second electronic switch 82, and the magnetic stimulation coil 79 generates a reverse magnetic field;
the processor 2 receives the feedback signal (the magnetic field waveform state signal and the energy storage state signal of the energy storage element) of the fourth single chip 51 and uploads the feedback signal to the computer 1, and the touch screen of the computer 1 displays the waveform of the magnetic field of the magnetic stimulation coil 79 and the energy storage state of the energy storage element 78.
The invention is not limited solely to that described in the specification and embodiments, and additional advantages and modifications will readily occur to those skilled in the art, so that the invention is not limited to the specific details, representative apparatus, and examples shown and described herein, without departing from the spirit and scope of the general concept as defined by the appended claims and their equivalents.

Claims (8)

1. A magnetic shock therapeutic apparatus comprises a computer (1), a processor (2), an acquisition module (3), a human-computer interaction module (4), a control signal generation module (5), a cooling device (6), a charging and discharging system (7) and an electronic switch group (8); it is characterized in that the preparation method is characterized in that,
the processor (2) is in communication connection with the computer (1), the acquisition module (3), the human-computer interaction module (4) and the control signal generation module (5) are in communication connection with the processor (2), and the cooling device (6) is electrically connected with the control signal generation module (5); the charging and discharging system (7) comprises a first power factor corrector (70), a first charging module (71), a second power factor corrector (72), a second charging module (73), a third power factor corrector (74), a third charging module (75), a fourth power factor corrector (76), a fourth charging module (77), an energy storage element (78) and a magnetic stimulation coil (79), wherein the control signal generating module (5) is in communication connection with the first charging module (71), the second charging module (73), the third charging module (75) and the fourth charging module (77);
the first end of the first power factor corrector (70), the first end of the second power factor corrector (72), the first end of the third power factor corrector (74) and the first end of the fourth power factor corrector (76) are all connected with a three-phase power supply, and the second end of the first power factor corrector (70), the second end of the second power factor corrector (72), the second end of the third power factor corrector (74) and the second end of the fourth power factor corrector (76) are respectively electrically connected with the first charging module (71), the second charging module (73), the third charging module (75) and the fourth charging module (77);
the anode of the first charging module (71), the anode of the second charging module (73), the anode of the third charging module (75) and the anode of the fourth charging module (77) are electrically connected with the anode of the energy storage element (78), and the cathode of the first charging module (71), the cathode of the second charging module (73), the cathode of the third charging module (75) and the cathode of the fourth charging module (77) are electrically connected with the cathode of the energy storage element (78);
the first end of magnetic stimulation coil (79) with the negative pole electric connection of energy storage component (78), electronic switch group (8) include first electronic switch (81) and second electronic switch (82), the second end of magnetic stimulation coil (79) with the negative pole of first electronic switch (81) and the positive pole electric connection of second electronic switch (82), the positive pole of first electronic switch (81) and the negative pole of second electronic switch (82) with the positive pole electric connection of energy storage component (78), the control utmost point of first electronic switch (81) with control signal generates module (5) communication connection.
2. The magnetic shock therapy apparatus according to claim 1, wherein the first acquisition module (3) comprises an acquisition unit (30), a preamplifier (31), a notch filter (32), a program controlled amplifier (33), a band pass filter (34), an a/D converter (35), a first single chip microcomputer (36), a digital signal processor (37), a first isolation transceiver and a first surge protector; the acquisition unit (30), the preamplifier (31), the notch filter (32), the program-controlled amplifier (33), the band-pass filter (34), the A/D converter (35), the first single chip microcomputer (36) and the digital signal processor (37) are electrically connected in sequence, the first single chip microcomputer (36) is electrically connected with the program-controlled amplifier (33), the first isolation transceiver is electrically connected with the first surge protector, and the first surge protector is electrically connected between the program-controlled amplifier (33) and the first single chip microcomputer (36).
3. The magnetic shock therapy apparatus according to claim 1, wherein the cooling device (6) comprises a second isolation transceiver, a second surge protector, a second single chip microcomputer (60), an isolator (61), a water pump (62), an air pump (63), a water tank (64), a flow sensor (65) and a temperature sensor (66); transceiver, second surge protector, second singlechip (60), isolator (61) electric connection in proper order are kept apart to the second, water pump (62) and air pump (63) all with isolator (61) electric connection, just water pump (62) and air pump (63) all with water tank (64) are connected, water tank (64) of cooling device (6) with magnetism stimulating coil (79) are connected, flow sensor (65) and temperature sensor (66) all with second singlechip (60) electric connection, the coolant liquid has been held in water tank (64).
4. A magnetic shock therapy device according to claim 3, characterized in that said cooling means (6) further comprises a fan (67), said fan (67) being arranged adjacent to said water pump (62) and being electrically connected to said isolator (61).
5. A magnetic shock therapy device according to claim 3, characterized in that said cooling means (6) further comprises a hydraulic pressure sensor (68) and a level sensor (69); hydraulic pressure sensor (68) with second singlechip (60) electric connection, level sensor (69) with second singlechip (60) electric connection and being located in water tank (64), hydraulic pressure sensor (68) are used for detecting cooling liquid pressure and upload to the hydraulic information that detects second singlechip (60), level sensor (68) are used for detecting the liquid level in the water tank and upload to the liquid level information that detects second singlechip (60), second singlechip (60) pass through liquid level information and hydraulic information treater (2) upload to computer (1).
6. The magnetic shock therapeutic apparatus according to claim 1, wherein the human-computer interaction module (4) comprises a key matrix (41), a third single chip microcomputer (42), a sounder (43), a third isolation transceiver and a third surge protector, the key matrix (41), the sounder (43), the third isolation transceiver and the third surge protector are all electrically connected with the third single chip microcomputer (42), and the third single chip microcomputer (42) is in communication connection with the processor (2).
7. The magnetic shock therapeutic apparatus according to claim 6, wherein the human-computer interaction module (4) further comprises a breathing lamp (44) and a programmable driver (45), and the programmable driver (45) is electrically connected between the third singlechip (42) and the breathing lamp (44).
8. The magnetic shock therapeutic apparatus according to claim 1, wherein the control signal generating module (5) comprises a fourth isolating transceiver, a fourth surge protector, a fourth single chip microcomputer (51) and a photoelectric isolating chip (52), and the fourth isolating transceiver, the fourth surge protector and the photoelectric isolating chip (52) are electrically connected with the fourth single chip microcomputer (51).
CN202110081621.7A 2021-01-21 2021-01-21 Magnetic shock therapeutic instrument Active CN112891748B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110081621.7A CN112891748B (en) 2021-01-21 2021-01-21 Magnetic shock therapeutic instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110081621.7A CN112891748B (en) 2021-01-21 2021-01-21 Magnetic shock therapeutic instrument

Publications (2)

Publication Number Publication Date
CN112891748A true CN112891748A (en) 2021-06-04
CN112891748B CN112891748B (en) 2023-01-06

Family

ID=76117944

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110081621.7A Active CN112891748B (en) 2021-01-21 2021-01-21 Magnetic shock therapeutic instrument

Country Status (1)

Country Link
CN (1) CN112891748B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114610112A (en) * 2022-01-25 2022-06-10 湖南华医电磁医学研究院有限公司 Magnetic shock therapeutic instrument

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204522012U (en) * 2015-03-18 2015-08-05 夏显功 A kind of multifunction electric Magnetotherapeutic apparatus
US20160184601A1 (en) * 2013-06-21 2016-06-30 Technische Universität München Magnetic stimulator for stimulating tissue with a magnetic field
CN105879219A (en) * 2015-02-10 2016-08-24 北京大学 Multi-channel high-voltage pulse power generator for transcranial magnetic stimulation
CN107485787A (en) * 2017-09-12 2017-12-19 北京大学 It is a kind of for four loop constructions of transcranial magnetic stimulation and its application
CN109276814A (en) * 2018-10-31 2019-01-29 北京大学(天津滨海)新代信息技术研究院 Multi-channel stimulation system and method for transcranial magnetic stimulation
US20190030357A1 (en) * 2017-07-31 2019-01-31 Shenzhen Shengli Technology Co., Ltd Transcranial magnetic stimulation circuit, transcranial magnetic stimulator and magnetic impulse generation method thereof
CN109621207A (en) * 2018-12-24 2019-04-16 北京神畅科技发展有限公司 A kind of Novel warp cranium magnetic stimulation system and its high voltage charging power supply management method
CN209645654U (en) * 2018-11-26 2019-11-19 中国信息通信研究院 Noninvasive vagus nerve magnetic stimulation device
CN209917083U (en) * 2019-01-30 2020-01-10 江西京新医疗科技有限公司 50Hz magnetic shock device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160184601A1 (en) * 2013-06-21 2016-06-30 Technische Universität München Magnetic stimulator for stimulating tissue with a magnetic field
CN105879219A (en) * 2015-02-10 2016-08-24 北京大学 Multi-channel high-voltage pulse power generator for transcranial magnetic stimulation
CN204522012U (en) * 2015-03-18 2015-08-05 夏显功 A kind of multifunction electric Magnetotherapeutic apparatus
US20190030357A1 (en) * 2017-07-31 2019-01-31 Shenzhen Shengli Technology Co., Ltd Transcranial magnetic stimulation circuit, transcranial magnetic stimulator and magnetic impulse generation method thereof
CN107485787A (en) * 2017-09-12 2017-12-19 北京大学 It is a kind of for four loop constructions of transcranial magnetic stimulation and its application
CN109276814A (en) * 2018-10-31 2019-01-29 北京大学(天津滨海)新代信息技术研究院 Multi-channel stimulation system and method for transcranial magnetic stimulation
CN209645654U (en) * 2018-11-26 2019-11-19 中国信息通信研究院 Noninvasive vagus nerve magnetic stimulation device
CN109621207A (en) * 2018-12-24 2019-04-16 北京神畅科技发展有限公司 A kind of Novel warp cranium magnetic stimulation system and its high voltage charging power supply management method
CN209917083U (en) * 2019-01-30 2020-01-10 江西京新医疗科技有限公司 50Hz magnetic shock device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
廖家华等: "磁休克的基本原理及关键技术", 《中国医疗设备》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114610112A (en) * 2022-01-25 2022-06-10 湖南华医电磁医学研究院有限公司 Magnetic shock therapeutic instrument

Also Published As

Publication number Publication date
CN112891748B (en) 2023-01-06

Similar Documents

Publication Publication Date Title
Mölle et al. The influence of learning on sleep slow oscillations and associated spindles and ripples in humans and rats
CN101085391B (en) Device for inducing tumor cell apoptosis by high-voltage nanosecond pulse
JP6254281B2 (en) EEG measurement and brain stimulation system
JP2023500747A (en) Multi-target electrical stimulation circuit, electrical stimulation device and signal output method thereof
Yi et al. A blink restoration system with contralateral EMG triggered stimulation and real-time artifact blanking
CN109621156A (en) A kind of brain electricity reaction type microcurrent stimulating sleep assistance instrument and application method
CN112827066A (en) Multifunctional transcranial stimulation magnetic therapy device
CN201453834U (en) Therapeutic instrument for curing computer disease through transcranial magnetic stimulation
CN105664357A (en) Multi-parameter adjustable transcranial current stimulation system
CN112891748B (en) Magnetic shock therapeutic instrument
WO2023201863A1 (en) Method and system for closed-loop regulation of neural network by adaptive alternating current stimulation
CN102058396B (en) Handheld cortex egersimeter and cortex electrostimulation
CN101537228A (en) Transcranial magnetic therapeutic instrument for computer diseases
CN109821151A (en) A kind of multi-electrode electric pulse stimulation acupuncture point tinnitus therapeutic apparatus and its stimulation protocol based on Bluetooth communication control
CN110522998B (en) Transcranial electromagnetic rehabilitation therapeutic apparatus
JP2007050258A (en) Electric stimulating device for nervous system
Plachta et al. BaroLoop: Using a multichannel cuff electrode and selective stimulation to reduce blood pressure
WO2021248914A1 (en) Mental fatigue intervention device and method
CN112755395B (en) True and false pulse magnetic stimulation therapeutic instrument
CN104841057A (en) Electroencephalogram brainwave alpha based infrasonic wave driving fatigue relieving method and device
CN202143753U (en) Transcranial magnetic biofeedback apparatus
CN201798739U (en) Anti-jamming myoelectricity acquisition device for transcranial magnetic stimulation instrument
CN205287243U (en) A device for treating chronic pain
CN112023263A (en) Remote monitoring household high-precision transcranial current stimulation system
Schutter et al. A case of illusory own-body perceptions after transcranial magnetic stimulation of the cerebellum

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant