CN111735958B - Processing system and method of full-automatic enzyme immunoassay analyzer - Google Patents

Processing system and method of full-automatic enzyme immunoassay analyzer Download PDF

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Publication number
CN111735958B
CN111735958B CN202010635575.6A CN202010635575A CN111735958B CN 111735958 B CN111735958 B CN 111735958B CN 202010635575 A CN202010635575 A CN 202010635575A CN 111735958 B CN111735958 B CN 111735958B
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China
Prior art keywords
plate
washing liquid
wall
pure water
lifting
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CN202010635575.6A
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CN111735958A (en
Inventor
唐建华
陈富强
肖晨
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BLOOD CENTER OF SHANDONG PROVINCE
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BLOOD CENTER OF SHANDONG PROVINCE
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures

Abstract

The invention discloses a treatment system of a full-automatic enzyme immunoassay analyzer, which belongs to the technical field of post-treatment systems of full-automatic enzyme immunoassay analyzers, and comprises a wall-mounted container, a pure water faucet, a table, a transfer cart, a full-automatic enzyme immunoassay analyzer and a controller, wherein the wall-mounted container is fixedly connected to a wall surface through screws, the table is arranged below the wall-mounted container, the pure water faucet is arranged on the wall surface close to the wall-mounted container, and the controller is arranged near the wall-mounted container.

Description

Processing system and method of full-automatic enzyme immunoassay analyzer
Technical Field
The invention relates to the technical field of post-processing systems of full-automatic enzyme immunoassay analyzers, in particular to a processing system and a processing method of a full-automatic enzyme immunoassay analyzer.
Background
A post-treatment system for a full-automatic enzyme immunoassay analyzer (FAME, manufactured by Australian Pont). The analyzer is used for 4 enzyme-free automatic detection projects of HBsAg, HCVAg/Ab, anti-HIV-1 +2, anti-HIV-1, anti-HIV-2 and p24 antigens (HIVAg/Ab1+2) and anti-TP, and the test is called enzyme-linked immunosorbent assay (ELISA). Each detection item is divided into an initial detection test and a retest test, and 8 detection methods are used in total. The reagents of the 8 detection methods are respectively contained in corresponding kits and comprise components such as test washing liquid and the like. An operator needs to dilute the prepared washing liquid with purified water according to the reagent specification and then manually load the washing liquid into a corresponding washing liquid barrel. The liquid washing barrel is moved by the cart from the preparation workbench to the side of the machine and is manually placed at a corresponding position on the machine.
The volumes of the washing solutions in the reagent boxes of different manufacturers are different, and the washing solutions are contained in washing solution bottles with different specifications; before the experiment, the sample is diluted by purified water according to the dilution times, put into a washing liquid barrel and loaded on FAME for the experiment. The washing liquid used in the test is various in types and large in preparation amount, the washing liquid is prepared from the finished product washing liquid, the washing liquid is added into a washing liquid barrel according to the capacity of the required washing liquid, and then the pure water is added to dilute the washing liquid to the corresponding concentration, so that the operation is complicated. And each barrel prepared with the washing liquid is heavier, and the placing position of the washing liquid barrel is higher. When the lifting mechanism is manually moved in and out of a common cart and lifted and moved into a machine, the placing is laborious. Since the washing liquid barrel is heavy and difficult to maintain a horizontal posture when being taken and put, the bottom of the far end of the washing liquid barrel (especially one corner of the barrel) is usually contacted with the inner wall of the cart or the machine firstly and then is placed on the cart or the machine by force pushing or sliding. This process inevitably causes wear of the outer shell of the distal bottom of the tub, which has been found to be damaged and leakage occurring during operation, but the cost of replacing the wash tub is high.
Based on the above, the invention designs a processing system and a method of a full-automatic enzyme immunoassay analyzer, so that the configuration process and the moving process of the washing liquid are more convenient.
Disclosure of Invention
The invention aims to provide a processing system and a processing method of a full-automatic enzyme immunoassay analyzer, which aim to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a processing system of a full-automatic enzyme immunoassay analyzer comprises a wall-mounted container, a pure water faucet, a table plate, a transfer cart, the full-automatic enzyme immunoassay analyzer and a controller, wherein the wall-mounted container is fixedly connected to a wall surface through screws, the table plate is arranged below the wall-mounted container, the pure water faucet is arranged on the wall surface close to the wall-mounted container, and the controller is installed near a wall cabinet container; .
Pure water flow switches are arranged on the pure water taps, and the controller is electrically connected with the pure water flow switches;
the transfer cart comprises a bottom plate, rollers are arranged at the bottom of the bottom plate, a conveying device and a lifting device are arranged at the top of the bottom plate, and the lifting device is arranged on the output side of the conveying device.
Preferably, the hanging container is including the box, the inner chamber of box is separated for a plurality of unidimensional lotion chambeies, the bottom in lotion chamber is equipped with the outlet pipe, every all be equipped with lotion flow switch on the outlet pipe, every lotion flow switch all with controller electric connection, the top in lotion chamber is equipped with adds the liquid mouth, it has the detachable closing cap to fill in on the liquid mouth to add, the lateral wall all is provided with the connecting plate about the box, it has the connecting hole to open on the connecting plate.
Preferably, the box body is made of transparent materials and can be made of transparent plastics or anticorrosive glass.
Preferably, the conveying device comprises a mounting seat arranged on the bottom plate, and a conveying belt is arranged on the mounting seat.
Preferably, elevating gear is including lift actuating mechanism, the last lift connecting block that installs of lift actuating mechanism, one side that the lift connecting block is close to the conveyer belt is equipped with the bearing board, install on one side lateral wall of bearing board and push away the material cylinder, the output that pushes away the material cylinder is equipped with the flat push pedal, the flat push pedal is L template body structure.
Preferably, the lifting driving mechanism is including U type frame, the vertical rigid coupling of U type frame is on the bottom plate, and U type frame opening down, the diaphragm bottom middle part of U type frame is rotated and is equipped with the lead screw, the lead screw bottom is rotated and is connected the bottom plate, the top of lead screw is connected with elevator motor, the bilateral symmetry of lead screw is equipped with the gag lever post, the lift connecting block runs through the spiro union on the lead screw, and the spacing activity of gag lever post runs through the lift connecting block.
Preferably, the bearing plate comprises an L-shaped plate, a mounting plate is arranged on the left side of the L-shaped plate, the material pushing cylinder is arranged on the mounting plate, and the top surfaces of the bottom plates of the L-shaped plate are provided with roller columns at equal intervals.
A method for using a processing system of a full-automatic enzyme immunoassay analyzer comprises the following steps:
s1, a user places the washing liquid barrel at the position of the water outlet pipe corresponding to the washing liquid, the outflow quantity of the washing liquid is set through the controller 6, and a certain quantity of the corresponding washing liquid is input into the washing liquid barrel under the control of the washing liquid flow switch 14;
s2, placing the washing liquid barrel under the pure water faucet 2, setting the pure water outflow through the controller 6, and inputting quantitative pure water into the washing liquid barrel under the control of the pure water flow switch 21;
s3, placing the washing liquid barrel on the conveyor belt 44 of the transfer cart 4 after shaking the washing liquid barrel uniformly, and pushing the cart to move to the front position of the full-automatic enzyme immunoassay analyzer 5;
s4, starting the conveyor belt 44, horizontally moving a group of washing liquid barrels to the bearing plate 47, then starting the lifting motor, and lifting and driving through the screw rod to enable the bearing plate 47 to move to a corresponding height;
s5, starting the material pushing cylinder 48, and horizontally pushing the washing liquid barrel into the full-automatic enzyme immunoassay analyzer 5 by the flat pushing plate 49 for analysis and detection.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, through the arrangement of the wall-mounted container, the flow switch and other structures, the washing liquid is more accurately configured, the operation is simple and quick, and the pollution caused by the leakage of the washing liquid can be reduced;
2. through the wall-mounted container, the flow switch and other structures, the washing liquid can be more accurately configured, the operation is simple and quick, and the pollution caused by the leakage of the washing liquid can be reduced.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of a wall-mounted container according to the present invention;
FIG. 3 is a schematic view of the structure of the transfer cart of the present invention
FIG. 4 is a schematic structural view of a transfer cart without a conveying device according to the present invention;
FIG. 5 is a schematic view of the structure of the support plate of the present invention.
The reference numbers are as follows:
1-wall-mounted container, 2-pure water faucet, 21-pure water flow switch, 3-table, 4-transfer cart, 5-full-automatic enzyme immunoassay analyzer, 6-controller, 11-box, 12-lotion cavity, 13-water outlet pipe, 14-lotion flow switch, 15-liquid adding port, 16-detachable sealing cover, 17-connecting plate, 41-bottom plate, 42-roller, 43-mounting seat, 44-conveyor belt, 45-lifting driving mechanism, 46-lifting connecting block, 47-bearing plate, 48-material pushing cylinder, 49-flat pushing plate, 451-U-shaped frame, 452-screw rod, 453-lifting motor, 454-limiting rod, 471-L-shaped plate, 472-mounting plate and 473-roller column.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1 to 5, the present invention provides a technical solution: a processing system of a full-automatic enzyme immunoassay analyzer comprises a wall-mounted container 1, a pure water faucet 2, a table plate 3, a transfer cart 4, a full-automatic enzyme immunoassay analyzer 5 and a controller 6, wherein the wall-mounted container 1 is fixedly connected to a wall surface through screws, the table plate 3 is arranged below the wall-mounted container 1, the pure water faucet 2 is arranged on the wall surface close to the wall-mounted container 1, and the controller 6 is arranged near the wall-mounted container 1; .
Pure water flow switches 21 are arranged on the pure water taps 2, and the controller 6 is electrically connected with the pure water flow switches 21;
the transfer cart 4 comprises a bottom plate 41, rollers 42 are arranged at the bottom of the bottom plate 41, a conveying device and a lifting device are arranged at the top of the bottom plate 41, and the lifting device is arranged at the output side of the conveying device.
Further, hanging container 1 is including box 11, box 11's inner chamber is separated for a plurality of the same size's lotion chamber 12, the bottom in lotion chamber 12 is equipped with outlet pipe 13, all be equipped with lotion flow switch 14 on every outlet pipe 13, every lotion flow switch 14 all with 6 electric connection of controller, the top in lotion chamber 12 is equipped with adds liquid mouth 15, it has detachable closing cap 16 to fill in on the liquid mouth 15, box 11 all is provided with connecting plate 17 about, it has the connecting hole to open on connecting plate 17.
Wherein the number of washing reagent chambers 12 can be 6 or 8.
Further, the box body 11 is made of transparent materials, and can be made of transparent plastics or anticorrosive glass, so that the washing liquid capacity can be conveniently observed, and the washing liquid can be added in time.
Further, the conveying device comprises a mounting seat 43 arranged on the bottom plate 41, and a conveying belt 44 is arranged on the mounting seat 43.
Further, the lifting device comprises a lifting driving mechanism 45, a lifting connecting block 46 is mounted on the lifting driving mechanism 45, a bearing plate 47 is arranged on one side, close to the conveyor belt 44, of the lifting connecting block 46, a material pushing cylinder 48 is mounted on the side wall of one side of the bearing plate 47, a flat pushing plate 49 is arranged at the output end of the material pushing cylinder 48, the flat pushing plate 49 is of an L-shaped plate structure, and when the washing liquid barrel is pushed out, the front end of the washing liquid barrel is prevented from inclining to cause abrasion.
Further, the lifting driving mechanism 45 comprises a U-shaped frame 451, the U-shaped frame 451 is vertically fixedly connected to the bottom plate 41, an opening of the U-shaped frame 451 faces downward, a screw rod 452 is rotatably arranged in the middle of the bottom end of a transverse plate of the U-shaped frame 451, the bottom end of the screw rod 452 is rotatably connected to the bottom plate 41, the top end of the screw rod 452 is connected to a lifting motor 453, limit rods 454 are symmetrically arranged on two sides of the screw rod 452, the lifting connecting block 46 is in threaded connection with the screw rod 452, and the limit rods 452 are in limit movable penetrating through the lifting connecting block 46.
Further, the supporting plate 47 comprises an L-shaped plate 471, an installation plate 472 is arranged on the left side of the L-shaped plate 471, the material pushing cylinder 48 is arranged on the installation plate 472, the roller columns 473 are arranged on the top surface of the bottom plate of the L-shaped plate 471 at equal intervals, and friction loss of the washing liquid barrel can be reduced in a rolling conveying mode.
A method for using a processing system of a full-automatic enzyme immunoassay analyzer comprises the following steps:
s1, a user places the washing liquid barrel at the position of the water outlet pipe corresponding to the washing liquid, the outflow quantity of the washing liquid is set through the controller 6, and a certain quantity of the corresponding washing liquid is input into the washing liquid barrel under the control of the washing liquid flow switch 14;
s2, placing the washing liquid barrel under the pure water faucet 2, setting the pure water outflow through the controller 6, and inputting quantitative pure water into the washing liquid barrel under the control of the pure water flow switch 21;
s3, placing the washing liquid barrel on the conveyor belt 44 of the transfer cart 4 after shaking the washing liquid barrel uniformly, and pushing the cart to move to the front position of the full-automatic enzyme immunoassay analyzer 5;
s4, starting the conveyor belt 44, horizontally moving a group of washing liquid barrels to the bearing plate 47, then starting the lifting motor, and lifting and driving through the screw rod to enable the bearing plate 47 to move to a corresponding height;
s5, starting the material pushing cylinder 48, and horizontally pushing the washing liquid barrel into the full-automatic enzyme immunoassay analyzer 5 by the flat pushing plate 49 for analysis and detection.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The above disclosure of further embodiments of the invention is intended only to facilitate the explanation of the invention. Further examples are not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims (3)

1. The utility model provides a processing apparatus of full-automatic enzyme immunoassay appearance which characterized in that: the treatment device comprises a wall-mounted container (1), a pure water faucet (2), a table plate (3), a transfer cart (4), a full-automatic enzyme immunoassay analyzer (5) and a controller (6), wherein the wall-mounted container (1) is fixedly connected to a wall surface through screws, the table plate (3) is arranged below the wall-mounted container (1), the pure water faucet (2) is arranged on the wall surface close to the wall-mounted container (1), and the controller (6) is arranged near the wall-mounted container (1);
pure water flow switches (21) are arranged on the pure water taps (2), and the controllers (6) are electrically connected with the pure water flow switches (21);
the transfer cart (4) comprises a bottom plate (41), rollers (42) are arranged at the bottom of the bottom plate (41), a conveying device and a lifting device are arranged at the top of the bottom plate (41), and the lifting device is arranged on the output side of the conveying device;
the conveying device comprises a mounting seat (43) arranged on a bottom plate (41), and a conveying belt (44) is arranged on the mounting seat (43);
the lifting device comprises a lifting driving mechanism (45), a lifting connecting block (46) is mounted on the lifting driving mechanism (45), a bearing plate (47) is arranged on one side, close to the conveyor belt (44), of the lifting connecting block (46), a material pushing cylinder (48) is mounted on the side wall of one side of the bearing plate (47), a flat push plate (49) is arranged at the output end of the material pushing cylinder (48), and the flat push plate (49) is of an L-shaped plate structure;
the lifting driving mechanism (45) comprises a U-shaped frame (451), the U-shaped frame (451) is vertically and fixedly connected to the bottom plate (41), an opening of the U-shaped frame (451) faces downwards, a screw rod (452) is rotatably arranged in the middle of the bottom end of a transverse plate of the U-shaped frame (451), the bottom end of the screw rod (452) is rotatably connected to the bottom plate (41), the top end of the screw rod (452) is connected with a lifting motor (453), limiting rods (454) are symmetrically arranged on two sides of the screw rod (452), the lifting connecting block (46) is in threaded connection with the screw rod (452) in a penetrating mode, and the limiting rods (454) are in limiting movable penetrating through the lifting connecting block (46);
the bearing plate (47) comprises an L-shaped plate (471), an installation plate (472) is arranged on the left side of the L-shaped plate (471), the material pushing cylinder (48) is arranged on the installation plate (472), and the top surface of the bottom plate of the L-shaped plate (471) is provided with roller columns (473) at equal intervals;
wall hanging container (1) is including box (11), the inner chamber of box (11) is separated for a plurality of the same size's lotion chamber (12), the bottom of lotion chamber (12) is equipped with outlet pipe (13), every all be equipped with lotion flow switch (14) on outlet pipe (13), every lotion flow switch (14) all with controller (6) electric connection, the top of lotion chamber (12) is equipped with adds liquid mouth (15), it has detachable closing cap (16) to fill in on liquid mouth (15), the lateral wall all is provided with connecting plate (17) about box (11), it has the connecting hole to open on connecting plate (17).
2. The processing device of the full-automatic enzyme immunoassay analyzer according to claim 1, wherein: the box body (11) is made of transparent materials and is made of transparent plastics or anticorrosive glass.
3. The method of claim 1, comprising the steps of:
s1, a user places the washing liquid barrel at the position of the water outlet pipe corresponding to the washing liquid, the outflow quantity of the washing liquid is set through the controller (6), and a certain quantity of the corresponding washing liquid is input into the washing liquid barrel under the control of the washing liquid flow switch (14);
s2, placing the washing liquid barrel under the pure water faucet (2), setting the pure water outflow through the controller (6), and inputting quantitative pure water into the washing liquid barrel under the control of the pure water flow switch (21);
s3, placing the washing liquid barrel on a conveyor belt (44) of a transfer cart (4) after shaking the washing liquid barrel uniformly, and pushing the cart to move to the front position of a full-automatic enzyme immunoassay analyzer (5);
s4, starting a conveyor belt (44), horizontally moving a group of washing liquid barrels to push the washing liquid barrels to a bearing plate (47), then starting a lifting motor, and enabling the bearing plate (47) to move to a corresponding height through lifting transmission of a screw rod;
s5, starting the material pushing cylinder (48), and horizontally pushing the washing liquid barrel into the full-automatic enzyme immunoassay analyzer (5) by the flat push plate (49) for analysis and detection.
CN202010635575.6A 2020-07-03 2020-07-03 Processing system and method of full-automatic enzyme immunoassay analyzer Active CN111735958B (en)

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CN111735958B true CN111735958B (en) 2021-07-23

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CN1053157C (en) * 1995-10-17 2000-06-07 上海联合邮政技术成套公司 Transmission and storage system for case type container
US6899848B1 (en) * 2001-02-27 2005-05-31 Hamilton Company Automated sample treatment system: apparatus and method
CN1448725A (en) * 2002-04-01 2003-10-15 北京贝斯特医用仪器有限公司 Method and apparatus for accomplishing ABO blood type full-automatic identification on full-automatic enzyme non-analysis meter
JP2013535193A (en) * 2010-07-23 2013-09-12 ベックマン コールター, インコーポレイテッド System and method including an analyzer
CN203094121U (en) * 2013-03-20 2013-07-31 山东省血液中心 Special shelving vehicle used for FAME
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CN109421776A (en) * 2017-08-25 2019-03-05 李志蓉 Trolley with lifting transmitting function
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JP7325171B2 (en) * 2018-03-29 2023-08-14 シスメックス株式会社 Rack transportation method, sample measurement system
CN209226134U (en) * 2018-09-29 2019-08-09 杭州智谷精工有限公司 Planar object feeding and conveyer system

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