BE901783A - Nouveaux esters enoliques precurseurs de medicaments et composition pharmaceutique les contenant. - Google Patents

Nouveaux esters enoliques precurseurs de medicaments et composition pharmaceutique les contenant.

Info

Publication number
BE901783A
BE901783A BE0/214544A BE214544A BE901783A BE 901783 A BE901783 A BE 901783A BE 0/214544 A BE0/214544 A BE 0/214544A BE 214544 A BE214544 A BE 214544A BE 901783 A BE901783 A BE 901783A
Authority
BE
Belgium
Prior art keywords
drugs
novel
pharmaceutical composition
composition containing
esters precursor
Prior art date
Application number
BE0/214544A
Other languages
English (en)
Inventor
G Lombardino Joseph
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE901783A publication Critical patent/BE901783A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Esters d'énols de formule ci-contre dans laquelle R1 est un groupe alcanoyle, aroyle, alkysulfonyle ou arylsulfonyle; R2 est un groupe 5-méthylisoxazole-3-yle ou 6-chloro-2-pyridyle et R3 est un groupe aroyle, alkylsufonyle ou arylsulfonyle. Les composés de l'invention sont des promédicaments utiles comme précurseurs d'oxicams anti-inflammatoires et analgésiques non estérifiés connus.
BE0/214544A 1984-02-23 1985-02-21 Nouveaux esters enoliques precurseurs de medicaments et composition pharmaceutique les contenant. BE901783A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58268484A 1984-02-23 1984-02-23

Publications (1)

Publication Number Publication Date
BE901783A true BE901783A (fr) 1985-08-21

Family

ID=24330094

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214544A BE901783A (fr) 1984-02-23 1985-02-21 Nouveaux esters enoliques precurseurs de medicaments et composition pharmaceutique les contenant.

Country Status (22)

Country Link
JP (1) JPS60184077A (fr)
KR (1) KR850006198A (fr)
AU (1) AU552478B2 (fr)
BE (1) BE901783A (fr)
DD (1) DD232045A5 (fr)
DE (1) DE3505576A1 (fr)
DK (1) DK81185A (fr)
ES (1) ES8606312A1 (fr)
FI (1) FI850742L (fr)
FR (1) FR2565980A1 (fr)
GB (1) GB2154585A (fr)
GR (1) GR850442B (fr)
HU (1) HUT37616A (fr)
IL (1) IL74407A0 (fr)
IT (1) IT1185514B (fr)
LU (1) LU85780A1 (fr)
NL (1) NL8500485A (fr)
NO (1) NO850725L (fr)
PL (1) PL252023A1 (fr)
PT (1) PT79988B (fr)
SE (1) SE8500889L (fr)
ZA (1) ZA851317B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623486A (en) * 1985-05-29 1986-11-18 Pfizer Inc. [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
US4610982A (en) * 1985-06-03 1986-09-09 Pfizer Inc. Anti-inflammatory benzo- and thieno-1,2-thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
WO2008044095A1 (fr) * 2006-10-11 2008-04-17 Techfields Biochem Co. Ltd Pro-médicaments d'oxicams solubles dans l'eau et chargés positivement et composés apparentés avec une vitesse de pénétration de la peau très élevée
AU2007354632B2 (en) 2007-06-04 2014-06-26 Techfields Inc Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses
MX362949B (es) 2008-12-04 2019-02-27 Yu Chongxi Composiciones de alta penetracion y sus aplicaciones.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591574A (en) * 1968-05-29 1971-07-06 American Home Prod Tri-n-phenylglycyl derivatives of insulin
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3704298A (en) * 1971-06-22 1972-11-28 Warner Lambert Co 4-acyloxy-3-(2-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,1-dioxides
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
JPS5714589A (en) * 1980-06-27 1982-01-25 Mitsui Toatsu Chem Inc Benzothiazine derivative, its preparation and drug composition
US4309427A (en) * 1981-01-15 1982-01-05 Pfizer Inc. Benzothiazine dioxide derivatives
IT8219486A0 (it) * 1982-02-05 1982-02-05 Chiesi Farma Spa Nuovi composti ad attivita'antiinfiammatoria, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1206525B (it) * 1982-12-10 1989-04-27 Zionale S R L A Roma Preparato anti-infiammatorio nonsteroideo, per il trattamento delle affezioni artroreumatiche e metodo per la sua preparazione

Also Published As

Publication number Publication date
SE8500889D0 (sv) 1985-02-22
IT1185514B (it) 1987-11-12
FI850742A0 (fi) 1985-02-22
DK81185D0 (da) 1985-02-22
GB8504355D0 (en) 1985-03-20
FI850742L (fi) 1985-08-24
DD232045A5 (de) 1986-01-15
ZA851317B (en) 1986-10-29
ES540590A0 (es) 1986-04-16
AU552478B2 (en) 1986-06-05
ES8606312A1 (es) 1986-04-16
PL252023A1 (en) 1985-11-05
LU85780A1 (fr) 1985-12-11
NO850725L (no) 1985-08-26
PT79988B (en) 1987-02-02
KR850006198A (ko) 1985-10-02
AU3906685A (en) 1985-09-05
GR850442B (fr) 1985-06-19
SE8500889L (sv) 1985-08-24
DE3505576A1 (de) 1985-09-05
NL8500485A (nl) 1985-09-16
DK81185A (da) 1985-09-10
IT8519585A0 (it) 1985-02-21
HUT37616A (en) 1986-01-23
JPS60184077A (ja) 1985-09-19
FR2565980A1 (fr) 1985-12-20
PT79988A (en) 1985-03-01
GB2154585A (en) 1985-09-11
IL74407A0 (en) 1985-05-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC.

Effective date: 19870228