ZA993528B - A compound for use in treating glaucoma and ischemic retinopathy. - Google Patents
A compound for use in treating glaucoma and ischemic retinopathy.Info
- Publication number
- ZA993528B ZA993528B ZA9903528A ZA993528A ZA993528B ZA 993528 B ZA993528 B ZA 993528B ZA 9903528 A ZA9903528 A ZA 9903528A ZA 993528 A ZA993528 A ZA 993528A ZA 993528 B ZA993528 B ZA 993528B
- Authority
- ZA
- South Africa
- Prior art keywords
- compound
- treating glaucoma
- ischemic retinopathy
- mammal
- retinopathy
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title abstract 2
- 208000017442 Retinal disease Diseases 0.000 title abstract 2
- 206010038923 Retinopathy Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000302 ischemic effect Effects 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Eye Examination Apparatus (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8674598P | 1998-05-26 | 1998-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA993528B true ZA993528B (en) | 2000-11-27 |
Family
ID=22200630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9903528A ZA993528B (en) | 1998-05-26 | 1999-05-25 | A compound for use in treating glaucoma and ischemic retinopathy. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0985414B1 (de) |
| JP (1) | JP2000026297A (de) |
| KR (2) | KR100469188B1 (de) |
| AT (1) | ATE247963T1 (de) |
| AU (1) | AU762037B2 (de) |
| CA (1) | CA2272665C (de) |
| DE (1) | DE69910706T2 (de) |
| DK (1) | DK0985414T3 (de) |
| ES (1) | ES2204067T3 (de) |
| HU (1) | HUP9901728A3 (de) |
| IL (1) | IL130052A0 (de) |
| MY (1) | MY133222A (de) |
| NZ (2) | NZ508246A (de) |
| PT (1) | PT985414E (de) |
| TW (1) | TW581678B (de) |
| ZA (1) | ZA993528B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003528085A (ja) * | 2000-03-17 | 2003-09-24 | アルコン，インコーポレイティド | 緑内障治療のための６−ヒドロキシ・インダゾール誘導体 |
| US6956036B1 (en) | 2000-03-17 | 2005-10-18 | Alcon, Inc. | 6-hydroxy-indazole derivatives for treating glaucoma |
| DE60133596D1 (de) * | 2000-06-02 | 2008-05-21 | Pfizer Prod Inc | S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie |
| ATE424825T1 (de) | 2001-07-20 | 2009-03-15 | Psychogenics Inc | Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2021262A1 (de) * | 1970-04-30 | 1971-11-11 | Cassella Farbwerke Mainkur Ag | Piperazinderivate |
| US4130646A (en) * | 1975-07-25 | 1978-12-19 | E. R. Squibb & Sons, Inc. | 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof |
| IE50867B1 (en) * | 1980-02-29 | 1986-08-06 | Kefalas As | Indane derivatives |
| EP0233728A1 (de) * | 1986-02-11 | 1987-08-26 | Takeda Chemical Industries, Ltd. | 1,4-Benzoxazin-Derivate, ihre Herstellung und Verwendung |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| US5350747A (en) * | 1989-07-07 | 1994-09-27 | Pfizer Inc | Heteroaryl piperazine antipsychotic agents |
| ZA9010081B (en) * | 1989-12-20 | 1991-10-30 | Merrell Dow Pharma | Method for the treatment of glaucoma |
| CA2036307C (en) * | 1990-03-08 | 2002-07-09 | Susan Jean Ward | 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method |
| WO1997042190A1 (en) * | 1996-05-07 | 1997-11-13 | Pfizer Inc. | Mesylate trihydrate salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2(1h)-indol-2-one (=ziprasidone), its preparation and its use as dopamine d2 antagonist |
-
1999
- 1999-05-05 EP EP99303513A patent/EP0985414B1/de not_active Expired - Lifetime
- 1999-05-05 PT PT99303513T patent/PT985414E/pt unknown
- 1999-05-05 DK DK99303513T patent/DK0985414T3/da active
- 1999-05-05 DE DE69910706T patent/DE69910706T2/de not_active Expired - Fee Related
- 1999-05-05 AT AT99303513T patent/ATE247963T1/de not_active IP Right Cessation
- 1999-05-05 ES ES99303513T patent/ES2204067T3/es not_active Expired - Lifetime
- 1999-05-19 IL IL13005299A patent/IL130052A0/xx unknown
- 1999-05-19 TW TW088108219A patent/TW581678B/zh not_active IP Right Cessation
- 1999-05-21 CA CA002272665A patent/CA2272665C/en not_active Expired - Fee Related
- 1999-05-24 MY MYPI99002034A patent/MY133222A/en unknown
- 1999-05-25 NZ NZ50824699A patent/NZ508246A/xx unknown
- 1999-05-25 KR KR10-1999-0018748A patent/KR100469188B1/ko not_active IP Right Cessation
- 1999-05-25 NZ NZ335952A patent/NZ335952A/xx unknown
- 1999-05-25 ZA ZA9903528A patent/ZA993528B/xx unknown
- 1999-05-25 AU AU31242/99A patent/AU762037B2/en not_active Ceased
- 1999-05-25 HU HU9901728A patent/HUP9901728A3/hu unknown
- 1999-05-26 JP JP11146192A patent/JP2000026297A/ja active Pending
-
2003
- 2003-10-22 KR KR10-2003-0073635A patent/KR20030086544A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990088520A (ko) | 1999-12-27 |
| EP0985414B1 (de) | 2003-08-27 |
| DE69910706D1 (de) | 2003-10-02 |
| EP0985414A3 (de) | 2000-04-05 |
| MY133222A (en) | 2007-10-31 |
| KR100469188B1 (ko) | 2005-01-31 |
| KR20030086544A (ko) | 2003-11-10 |
| CA2272665C (en) | 2003-08-05 |
| HUP9901728A2 (hu) | 2000-12-28 |
| NZ335952A (en) | 2001-01-26 |
| AU3124299A (en) | 1999-12-02 |
| ES2204067T3 (es) | 2004-04-16 |
| ATE247963T1 (de) | 2003-09-15 |
| IL130052A0 (en) | 2000-02-29 |
| AU762037B2 (en) | 2003-06-19 |
| PT985414E (pt) | 2004-01-30 |
| DK0985414T3 (da) | 2003-12-29 |
| CA2272665A1 (en) | 1999-11-26 |
| EP0985414A2 (de) | 2000-03-15 |
| NZ508246A (en) | 2004-12-24 |
| JP2000026297A (ja) | 2000-01-25 |
| DE69910706T2 (de) | 2004-07-08 |
| HUP9901728A3 (en) | 2001-01-29 |
| TW581678B (en) | 2004-04-01 |
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