ZA985214B - Compounds useful for inhibition of farnesyl protein transferase - Google Patents

Compounds useful for inhibition of farnesyl protein transferase

Info

Publication number
ZA985214B
ZA985214B ZA985214A ZA985214A ZA985214B ZA 985214 B ZA985214 B ZA 985214B ZA 985214 A ZA985214 A ZA 985214A ZA 985214 A ZA985214 A ZA 985214A ZA 985214 B ZA985214 B ZA 985214B
Authority
ZA
South Africa
Prior art keywords
inhibition
compounds useful
protein transferase
farnesyl protein
farnesyl
Prior art date
Application number
ZA985214A
Inventor
Alan B Cooper
Jagdish A Desai
Anil K Saksena
Viyyoor M Girjavallabhan
James J-S Wang
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA985214B publication Critical patent/ZA985214B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA985214A 1997-06-17 1998-06-15 Compounds useful for inhibition of farnesyl protein transferase ZA985214B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87774397A 1997-06-17 1997-06-17

Publications (1)

Publication Number Publication Date
ZA985214B true ZA985214B (en) 1999-01-07

Family

ID=25370623

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985214A ZA985214B (en) 1997-06-17 1998-06-15 Compounds useful for inhibition of farnesyl protein transferase

Country Status (13)

Country Link
EP (1) EP0989984A1 (en)
JP (1) JP2002504145A (en)
KR (1) KR20010013825A (en)
CN (1) CN1266432A (en)
AR (1) AR015122A1 (en)
AU (1) AU744153B2 (en)
CA (1) CA2293713C (en)
CO (1) CO4940447A1 (en)
HU (1) HUP0004274A3 (en)
IL (1) IL133388A0 (en)
NZ (1) NZ501418A (en)
WO (1) WO1998057961A1 (en)
ZA (1) ZA985214B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010256360A1 (en) 2009-06-05 2012-01-12 Astrazeneca Ab Aminopyrrolidinone derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
JP2875393B2 (en) * 1993-10-15 1999-03-31 シェーリング コーポレイション Tricyclic carbamate compounds useful for inhibiting G-protein function and treating proliferative disorders
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Pharmaceutical compositions for inhibition of g-protein function and for treatment of proliferative diseases containing tricyclic compounds some such compounds and process for preparing part of them
SK86198A3 (en) * 1995-12-22 1999-02-11 Schering Corp Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
KR20010013825A (en) 2001-02-26
NZ501418A (en) 2001-04-27
CA2293713A1 (en) 1998-12-23
WO1998057961A1 (en) 1998-12-23
AU8058198A (en) 1999-01-04
HUP0004274A2 (en) 2001-08-28
AR015122A1 (en) 2001-04-18
HUP0004274A3 (en) 2002-03-28
JP2002504145A (en) 2002-02-05
AU744153B2 (en) 2002-02-14
IL133388A0 (en) 2001-04-30
EP0989984A1 (en) 2000-04-05
CA2293713C (en) 2006-12-05
CO4940447A1 (en) 2000-07-24
CN1266432A (en) 2000-09-13

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