ZA982454B - Method for treatment of chronic bronchitis using indole compounds. - Google Patents

Method for treatment of chronic bronchitis using indole compounds.

Info

Publication number
ZA982454B
ZA982454B ZA9802454A ZA982454A ZA982454B ZA 982454 B ZA982454 B ZA 982454B ZA 9802454 A ZA9802454 A ZA 9802454A ZA 982454 A ZA982454 A ZA 982454A ZA 982454 B ZA982454 B ZA 982454B
Authority
ZA
South Africa
Prior art keywords
treatment
chronic bronchitis
indole compounds
indole
compounds
Prior art date
Application number
ZA9802454A
Other languages
English (en)
Inventor
William Louis Macias
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA982454B publication Critical patent/ZA982454B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ZA9802454A 1997-03-26 1998-03-23 Method for treatment of chronic bronchitis using indole compounds. ZA982454B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4210197P 1997-03-26 1997-03-26

Publications (1)

Publication Number Publication Date
ZA982454B true ZA982454B (en) 1999-09-23

Family

ID=21920055

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9802454A ZA982454B (en) 1997-03-26 1998-03-23 Method for treatment of chronic bronchitis using indole compounds.

Country Status (8)

Country Link
US (1) US5972988A (enExample)
EP (1) EP1007046A4 (enExample)
JP (1) JP4347914B2 (enExample)
AU (1) AU6771798A (enExample)
CA (1) CA2284757A1 (enExample)
MY (1) MY114942A (enExample)
WO (1) WO1998042343A1 (enExample)
ZA (1) ZA982454B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2308443A1 (en) * 1997-10-27 1999-05-06 Michael Lyle Denney Morpholino-n-ethyl ester prodrugs of indole spla2 inhibitors
EP1030661A4 (en) * 1997-10-27 2002-07-17 Lilly Co Eli N, N-DIETHYLGLYCOLAMIDOESTER OF INDOLS AS PRELIMINARY MEDICINE OF SPLA 2 INHIBITORS
CZ302588B6 (cs) * 1998-04-02 2011-07-27 Ziopharm Oncology, Inc. Použití N-substituovaného indol-3-glyoxylamidu pro výrobu léciva
US6576654B1 (en) * 1998-09-23 2003-06-10 Eli Lilly And Company Method for the treatment of cystic fibrosis
US6274578B1 (en) 1999-04-20 2001-08-14 Eli Lilly And Company sPLA2 inhibitor ester
US6140327A (en) * 1999-05-12 2000-10-31 Eli Lilly And Company Morpholino-n-ethyl ester derivative of an indole sPLA2 inhibitor
WO2001044185A1 (en) * 1999-12-16 2001-06-21 Eli Lilly And Company Carbon monoxide-based synthesis of spla2 inhibitors
DE19962300A1 (de) * 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
WO2001081306A2 (en) * 2000-04-19 2001-11-01 Eli Lilly And Company Azide cyclization-based synthesis and intermediates for spla2 inhibitors
US20060035811A1 (en) * 2002-10-18 2006-02-16 Luis Molina Methods of treating dry eye disease with lantibiotics
CN1747936A (zh) * 2003-02-12 2006-03-15 特兰斯泰克制药公司 作为治疗试剂的取代吡咯衍生物
CA2565457A1 (en) * 2004-05-06 2005-11-17 Molichem Medicines, Inc. Treatment of membrane-associated diseases and disorders using lantibiotic containing compositions
CA2565545A1 (en) * 2004-05-06 2005-12-08 Molichem Medicines, Inc. Treatment of ocular diseases and disorders using lantibiotic compositions
US20150338425A1 (en) * 2011-11-14 2015-11-26 The Brigham And Women's Hospital, Inc. Treatment and prognosis of lymphangioleiomyomatosis
US9925202B2 (en) 2013-03-04 2018-03-27 Brigham And Women's Hospital, Inc. Treatment of lymphangioleiomyomatosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2341045A1 (en) * 1994-04-01 2011-07-06 Eli Lilly and Company [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-11H-indol-4-yl]oxy]acetic acid (acyloxy)alkyl or ((alkoxycarbonyl)oxy)alkyl ester as SPLA2 inhibitor

Also Published As

Publication number Publication date
JP4347914B2 (ja) 2009-10-21
MY114942A (en) 2003-02-28
AU6771798A (en) 1998-10-20
EP1007046A4 (en) 2000-11-29
WO1998042343A1 (en) 1998-10-01
JP2001524962A (ja) 2001-12-04
CA2284757A1 (en) 1998-10-01
EP1007046A1 (en) 2000-06-14
US5972988A (en) 1999-10-26

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