ZA973514B - New chiral phenyldihydrofuranones. - Google Patents
New chiral phenyldihydrofuranones.Info
- Publication number
- ZA973514B ZA973514B ZA9703514A ZA973514A ZA973514B ZA 973514 B ZA973514 B ZA 973514B ZA 9703514 A ZA9703514 A ZA 9703514A ZA 973514 A ZA973514 A ZA 973514A ZA 973514 B ZA973514 B ZA 973514B
- Authority
- ZA
- South Africa
- Prior art keywords
- pct
- phenyldihydrofuranones
- new chiral
- sec
- date
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19617864A DE19617864A1 (de) | 1996-04-23 | 1996-04-23 | Neue chirale Phenyldihydrofuranone |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA973514B true ZA973514B (en) | 1997-11-18 |
Family
ID=7793287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9703514A ZA973514B (en) | 1996-04-23 | 1997-04-23 | New chiral phenyldihydrofuranones. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6011060A (da) |
EP (1) | EP0900212B1 (da) |
JP (1) | JP2000510105A (da) |
AT (1) | ATE256673T1 (da) |
AU (1) | AU2949497A (da) |
DE (2) | DE19617864A1 (da) |
DK (1) | DK0900212T3 (da) |
ES (1) | ES2213214T3 (da) |
PT (1) | PT900212E (da) |
WO (1) | WO1997040032A1 (da) |
ZA (1) | ZA973514B (da) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19617864A1 (de) * | 1996-04-23 | 1997-10-30 | Schering Ag | Neue chirale Phenyldihydrofuranone |
US20040146561A1 (en) * | 2001-05-23 | 2004-07-29 | Naoki Sakurai | Compositions for promoting healing of bone fracture |
EP1389467B1 (en) * | 2001-05-23 | 2013-07-03 | Mitsubishi Tanabe Pharma Corporation | Therapeutic composition for the regenerative treatment of cartilage diseases |
TWI221838B (en) * | 2001-08-09 | 2004-10-11 | Tanabe Seiyaku Co | Pyrazinoisoquinoline compound or naphthalene compound |
US6962940B2 (en) * | 2002-03-20 | 2005-11-08 | Celgene Corporation | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
US20050148034A1 (en) * | 2002-04-12 | 2005-07-07 | Hariri Robert J. | Methods for identification of modulators of angiogenesis, compounds discovered thereby, and methods of treatment using the compounds |
AU2003262187A1 (en) * | 2002-04-12 | 2003-10-27 | Celgene Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
WO2005023253A1 (en) * | 2003-09-05 | 2005-03-17 | Altana Pharma Ag | Use of pde4 inhibitors for the treatment of diabetes mellitus |
EA015382B1 (ru) * | 2005-03-08 | 2011-08-30 | Никомед Гмбх | Применение рофлумиласта для лечения сахарного диабета типа 2 |
US7915429B2 (en) | 2006-01-25 | 2011-03-29 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2745320A1 (de) * | 1977-10-05 | 1979-04-19 | Schering Ag | 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung ii |
DE2655369A1 (de) * | 1976-12-03 | 1978-06-08 | Schering Ag | 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung |
WO1987006576A1 (en) * | 1986-04-29 | 1987-11-05 | Pfizer Inc. | Calcium independent camp phosphodiesterase inhibitor antidepressant |
JPH06501708A (ja) * | 1990-11-06 | 1994-02-24 | スミスクライン・ビーチャム・コーポレイション | イミダゾリジノン化合物 |
DK0660711T3 (da) * | 1992-09-14 | 1999-10-18 | Forssmann Wolf Georg Prof Dr | Hidtil ukendt anvendelse af phosphodiesterase IV-inhibitorer |
DE19617864A1 (de) * | 1996-04-23 | 1997-10-30 | Schering Ag | Neue chirale Phenyldihydrofuranone |
-
1996
- 1996-04-23 DE DE19617864A patent/DE19617864A1/de not_active Withdrawn
-
1997
- 1997-04-22 WO PCT/DE1997/000826 patent/WO1997040032A1/de active IP Right Grant
- 1997-04-22 EP EP97923757A patent/EP0900212B1/de not_active Expired - Lifetime
- 1997-04-22 AU AU29494/97A patent/AU2949497A/en not_active Abandoned
- 1997-04-22 JP JP09537603A patent/JP2000510105A/ja not_active Withdrawn
- 1997-04-22 DE DE59711138T patent/DE59711138D1/de not_active Expired - Fee Related
- 1997-04-22 DK DK97923757T patent/DK0900212T3/da active
- 1997-04-22 US US09/171,632 patent/US6011060A/en not_active Expired - Fee Related
- 1997-04-22 PT PT97923757T patent/PT900212E/pt unknown
- 1997-04-22 ES ES97923757T patent/ES2213214T3/es not_active Expired - Lifetime
- 1997-04-22 AT AT97923757T patent/ATE256673T1/de not_active IP Right Cessation
- 1997-04-23 ZA ZA9703514A patent/ZA973514B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT900212E (pt) | 2004-05-31 |
WO1997040032A1 (de) | 1997-10-30 |
DE19617864A1 (de) | 1997-10-30 |
DE59711138D1 (en) | 2004-01-29 |
ES2213214T3 (es) | 2004-08-16 |
ATE256673T1 (de) | 2004-01-15 |
EP0900212A1 (de) | 1999-03-10 |
EP0900212B1 (de) | 2003-12-17 |
DK0900212T3 (da) | 2004-04-19 |
JP2000510105A (ja) | 2000-08-08 |
US6011060A (en) | 2000-01-04 |
AU2949497A (en) | 1997-11-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA987491B (en) | Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation | |
HK1015269A1 (en) | Use of r-enantiomer of n-propargyl-1-aminoindan, salts, and compositions thereof | |
GB9423970D0 (en) | Oxidation | |
HUP0101625A3 (en) | New hydroxyindoles, their use as phosphodiesterase 4 inhibitors and method for producing same | |
TNSN97010A1 (fr) | Cyclopentanopyridyl-oxazolidinones contenant des heteroatomes. | |
WO2001078702A3 (en) | Methods and compositions for modulating alpha adrenergic receptor activity | |
AU2401697A (en) | 4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors | |
HK1027624A1 (en) | Solid-state fluorometer and methods of use therefor. | |
CA2406057A1 (en) | Methods and compositions for modulating alpha adrenergic receptor activity | |
DE60001735D1 (de) | 1-aminotriazolo 4,3-a chinazolin-5-one und/oder -thione inhibitoren von phosphodiesterasen iv | |
HK1019404A1 (en) | Injection formulations of avermectins or milbemycins based on castor oil, their preparation, and use of castor for preparing the same | |
ZA973514B (en) | New chiral phenyldihydrofuranones. | |
HK1040077A1 (en) | Substituted-3-cyano-[1.7], [1.5], and [1.8]-naphthyridine inhibitors of tyrosine kinases | |
ZA978089B (en) | 3,4-diaryloxazolone derivatives, their methods of preparation, and their use in therapeutics. | |
ZA989664B (en) | 3-substituted tetrahydropyrimidinone derivatives, their preparation and use. | |
HK1048318B (zh) | 取代的3-苯基-5-烷氧基-1,3,4-噁二唑-2-酮及其作為脂酶抑制劑的用途 | |
MX9700244A (es) | Utilizacion de un poliholosido en una composicion limpiadora o desmaquillante, y composicion que lo incluye. | |
AU4707101A (en) | Method and system for online third party referral system customized to the purchaser's needs | |
AU4178497A (en) | HTm4, methods of treatment and assays, agonists and antagonists | |
ZA9810625B (en) | Benzylidenepyrazolones, their preparation and use. | |
ZA989571B (en) | 2-Substituted 1,2-Benzoisonthiazole derivatives, their preparation and use. | |
ZA992192B (en) | Humectant and lubricant solution for ophthalmic use. | |
ZA966577B (en) | Pharmaceutical composition. | |
ZA966616B (en) | Benzenesulphonamide derivatives, their preparation and their application in theraphy. | |
AU6107999A (en) | 1,3-benzodiazepines with integrin inhibitory activity for use in the treatment of inflammatory disorders |