ZA972837B - Spray-dried microparticles as therapeutic vehicles for use in gene therapy. - Google Patents

Spray-dried microparticles as therapeutic vehicles for use in gene therapy.

Info

Publication number
ZA972837B
ZA972837B ZA9702837A ZA972837A ZA972837B ZA 972837 B ZA972837 B ZA 972837B ZA 9702837 A ZA9702837 A ZA 9702837A ZA 972837 A ZA972837 A ZA 972837A ZA 972837 B ZA972837 B ZA 972837B
Authority
ZA
South Africa
Prior art keywords
spray
gene therapy
dried microparticles
therapeutic vehicles
therapeutic
Prior art date
Application number
ZA9702837A
Other languages
English (en)
Inventor
Andrew Derek Sutton
Jill Elizabeth Ogden
Richard Alan Johnson
Original Assignee
Andaris Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andaris Ltd filed Critical Andaris Ltd
Publication of ZA972837B publication Critical patent/ZA972837B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA9702837A 1996-04-03 1997-04-03 Spray-dried microparticles as therapeutic vehicles for use in gene therapy. ZA972837B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9607035.4A GB9607035D0 (en) 1996-04-03 1996-04-03 Spray-dried microparticles as therapeutic vehicles
GB9601379 1996-06-07

Publications (1)

Publication Number Publication Date
ZA972837B true ZA972837B (en) 1998-04-03

Family

ID=26308516

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702837A ZA972837B (en) 1996-04-03 1997-04-03 Spray-dried microparticles as therapeutic vehicles for use in gene therapy.

Country Status (14)

Country Link
EP (1) EP0936902B1 (es)
JP (1) JP2000507568A (es)
AR (1) AR007493A1 (es)
AT (1) ATE243027T1 (es)
AU (1) AU715512B2 (es)
CA (1) CA2250478A1 (es)
DE (1) DE69722952T2 (es)
DK (1) DK0936902T3 (es)
ES (1) ES2201283T3 (es)
GB (1) GB9607035D0 (es)
NO (1) NO984462L (es)
PT (1) PT936902E (es)
WO (1) WO1997036578A1 (es)
ZA (1) ZA972837B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
AU717113B2 (en) 1995-11-09 2000-03-16 Health Protection Agency Microencapsulated DNA for vaccination and gene therapy
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US20030188679A1 (en) * 2000-08-25 2003-10-09 Eugen Schwarz Powdered mannitol and mannitol-containing compositions
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
EP2335689A1 (en) 2004-05-12 2011-06-22 Baxter International Inc. Method of manufacturing nucleic acid micropheres
ES2442115T3 (es) 2004-05-12 2014-02-10 Baxter International Inc. Microesferas que contienen oligonucleótidos, su utilización para la preparación de un medicamento para el tratamiento de la diabetes tipo 1
EP1834651A1 (en) * 2006-03-15 2007-09-19 Universiteit Gent Compositions and methods for veterinary vaccination
AU2007281737B2 (en) 2006-08-04 2013-09-19 Baxter Healthcare S.A. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
JP5744513B2 (ja) 2007-04-17 2015-07-08 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 肺送達のための核酸微小粒子
DE102009033196A1 (de) * 2009-07-14 2011-01-20 Beiersdorf Ag Kosmetische Zubereitung mit einem Gehalt an dispergierten Mikrosphären
SG11202100602SA (en) * 2018-07-23 2021-02-25 Translate Bio Inc Dry power formulations for messenger rna
CN113438943A (zh) * 2019-01-09 2021-09-24 辛克库姆公司 稳定的无包膜病毒组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5626871A (en) * 1992-06-12 1997-05-06 Teijin Limited Preparation for intratracheobronchial administration
DE69332240T2 (de) * 1992-06-12 2003-04-10 Teijin Ltd Ultrafeines pulver zur inhalation und dessen herstellung
WO1994023699A1 (en) * 1993-04-19 1994-10-27 Medisorb Technologies International L.P. Long-acting treatment by slow-release delivery of antisense oligodeoxyribonucleotides from biodegradable microparticles
NZ285664A (en) * 1994-05-18 1998-07-28 Inhale Therapeutic Syst Dry powder interferon composition adapted for pulmonary delivery
JPH10506406A (ja) * 1994-09-29 1998-06-23 アンダリス、リミテッド 治療用ビヒクルとしての噴霧乾燥させた微細粒子
AU5417796A (en) * 1995-03-07 1996-09-23 University Of Pittsburgh A dry powder formulation for gene therapy
JPH11510142A (ja) * 1995-07-21 1999-09-07 ブラウン・ユニバーシティ・リサーチ・ファンデーション 核酸負荷ポリマー微粒子を使用した遺伝子治療法

Also Published As

Publication number Publication date
AU715512B2 (en) 2000-02-03
DE69722952D1 (de) 2003-07-24
EP0936902B1 (en) 2003-06-18
CA2250478A1 (en) 1997-10-09
DK0936902T3 (da) 2003-10-06
ATE243027T1 (de) 2003-07-15
GB9607035D0 (en) 1996-06-05
AU2302097A (en) 1997-10-22
NO984462D0 (no) 1998-09-25
EP0936902A1 (en) 1999-08-25
ES2201283T3 (es) 2004-03-16
PT936902E (pt) 2003-11-28
WO1997036578A1 (en) 1997-10-09
DE69722952T2 (de) 2003-12-11
JP2000507568A (ja) 2000-06-20
AR007493A1 (es) 1999-11-10
NO984462L (no) 1998-09-25

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