ZA9710632B - New polymorphic form of doxazosin mesylate (form 1) - Google Patents

New polymorphic form of doxazosin mesylate (form 1)

Info

Publication number
ZA9710632B
ZA9710632B ZA9710632A ZA9710632A ZA9710632B ZA 9710632 B ZA9710632 B ZA 9710632B ZA 9710632 A ZA9710632 A ZA 9710632A ZA 9710632 A ZA9710632 A ZA 9710632A ZA 9710632 B ZA9710632 B ZA 9710632B
Authority
ZA
South Africa
Prior art keywords
doxazosin mesylate
new polymorphic
polymorphic form
new
doxazosin
Prior art date
Application number
ZA9710632A
Other languages
English (en)
Inventor
Grafe Ingomar Dr
Moersdorf Johann Peter Dr
Original Assignee
Heumann Pharma Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Pharma Gmbh & Co filed Critical Heumann Pharma Gmbh & Co
Publication of ZA9710632B publication Critical patent/ZA9710632B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
ZA9710632A 1996-12-20 1997-01-01 New polymorphic form of doxazosin mesylate (form 1) ZA9710632B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96120601A EP0849264A1 (de) 1996-12-20 1996-12-20 Neue polymorphe Form von doxazosinmesylat (Form I)

Publications (1)

Publication Number Publication Date
ZA9710632B true ZA9710632B (en) 1998-11-11

Family

ID=8223529

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710632A ZA9710632B (en) 1996-12-20 1997-01-01 New polymorphic form of doxazosin mesylate (form 1)

Country Status (10)

Country Link
US (1) US6130218A (xx)
EP (1) EP0849264A1 (xx)
JP (1) JPH10182639A (xx)
KR (1) KR19980064286A (xx)
CA (1) CA2224916A1 (xx)
HU (1) HUP9702480A3 (xx)
IL (1) IL122420A (xx)
NZ (1) NZ329404A (xx)
TW (1) TW420678B (xx)
ZA (1) ZA9710632B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19800214A1 (de) * 1998-01-06 1999-07-15 Knoll Ag Verfahren zur Herstellung von Doxazosin-Mcsylat in einer als Form A bezeichneten Kristallmodifikation und ein Zwischenprodukt dafür
US6706721B1 (en) * 1998-04-29 2004-03-16 Osi Pharmaceuticals, Inc. N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
ES2164520B1 (es) * 1999-03-16 2003-04-01 Medichem Sa "procedimiento de obtencion del polimorfo a del mesilato de doxazosina"
DE19912573A1 (de) * 1999-03-19 2000-09-21 Knoll Ag Arzneimittel, enthaltend Doxazosin-Mesylat der Kristallmodifikaton D
UA74803C2 (uk) * 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
US7087613B2 (en) * 1999-11-11 2006-08-08 Osi Pharmaceuticals, Inc. Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
JP2011507938A (ja) 2007-12-24 2011-03-10 シプラ・リミテッド メシル酸ドキサゾシンの結晶多形(形態iv)及びその製造方法
CN109988158A (zh) * 2018-01-03 2019-07-09 合肥立方制药股份有限公司 X晶型、含有x晶型的多沙唑嗪甲磺酸盐及其制备方法和用途
KR20190119416A (ko) 2018-04-12 2019-10-22 조선대학교산학협력단 다이빙 후드
CN111303130B (zh) * 2018-12-11 2021-09-14 合肥立方制药股份有限公司 一种多沙唑嗪甲磺酸盐晶型、其制备方法及用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2699054A (en) * 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
US4092315A (en) * 1976-03-01 1978-05-30 Pfizer Inc. Novel crystalline forms of prazosin hydrochloride
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4188390A (en) 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
DK154082C (da) * 1977-11-05 1989-02-27 Pfizer Analogifremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazolinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DE3683760D1 (de) * 1986-03-21 1992-03-12 Heumann Pharma Gmbh & Co Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
EP0459666B1 (en) * 1990-05-31 1994-11-09 Pfizer Inc. Medicaments against impotence
AU5457694A (en) * 1992-11-04 1994-05-24 Sepracor, Inc. Methods and compositions of (-) doxazosin for the treatment of benign prostatic hyperplasia and atherosclerosis
US5294615A (en) * 1993-04-29 1994-03-15 Abbott Laboratories Terazosin polymorph and pharmaceutical composition
US5412095A (en) * 1993-04-29 1995-05-02 Abbott Laboratories Terazosin monohydrochloride and processes and intermediate for its production
US5504207A (en) * 1994-10-18 1996-04-02 Abbott Laboratories Process and intermediate for the preparation of terazosin hydrochloride dihydrate

Also Published As

Publication number Publication date
IL122420A (en) 2000-06-01
HUP9702480A2 (hu) 1999-04-28
IL122420A0 (en) 1998-06-15
HU9702480D0 (en) 1998-03-02
CA2224916A1 (en) 1998-06-20
KR19980064286A (ko) 1998-10-07
HUP9702480A3 (en) 1999-06-28
AU4690497A (en) 1998-06-25
EP0849264A1 (de) 1998-06-24
NZ329404A (en) 1999-02-25
JPH10182639A (ja) 1998-07-07
AU720753B2 (en) 2000-06-08
US6130218A (en) 2000-10-10
TW420678B (en) 2001-02-01

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