ZA968597B - Lipid alcohols as new immunosuppressive and antiviral pharmaceutical agents. - Google Patents
Lipid alcohols as new immunosuppressive and antiviral pharmaceutical agents.Info
- Publication number
- ZA968597B ZA968597B ZA9608597A ZA968597A ZA968597B ZA 968597 B ZA968597 B ZA 968597B ZA 9608597 A ZA9608597 A ZA 9608597A ZA 968597 A ZA968597 A ZA 968597A ZA 968597 B ZA968597 B ZA 968597B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical agents
- antiviral pharmaceutical
- oxicarbonyl
- carbonylamido
- amidocarbonyl
- Prior art date
Links
- -1 Lipid alcohols Chemical class 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 230000001506 immunosuppresive effect Effects 0.000 title abstract 2
- 239000008177 pharmaceutical agent Substances 0.000 title abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000005708 carbonyloxy group Chemical group [*:2]OC([*:1])=O 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19538402A DE19538402A1 (de) | 1995-10-14 | 1995-10-14 | Lipidalkohole als neue immunsuppressive und antivirale Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA968597B true ZA968597B (en) | 1998-04-14 |
Family
ID=7774931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9608597A ZA968597B (en) | 1995-10-14 | 1996-10-11 | Lipid alcohols as new immunosuppressive and antiviral pharmaceutical agents. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6177469B1 (no) |
| EP (1) | EP0854708B1 (no) |
| JP (1) | JPH11513677A (no) |
| KR (1) | KR19990064240A (no) |
| AT (1) | ATE210434T1 (no) |
| AU (1) | AU722835B2 (no) |
| CA (1) | CA2234244A1 (no) |
| DE (2) | DE19538402A1 (no) |
| DK (1) | DK0854708T3 (no) |
| ES (1) | ES2169816T3 (no) |
| HU (1) | HUP9900725A3 (no) |
| IL (1) | IL123915A (no) |
| NO (1) | NO981629L (no) |
| NZ (1) | NZ320211A (no) |
| PT (1) | PT854708E (no) |
| TW (1) | TW426513B (no) |
| WO (1) | WO1997014410A1 (no) |
| ZA (1) | ZA968597B (no) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| US6406722B1 (en) | 1999-02-18 | 2002-06-18 | Robert G. Gallaher | Method of treating viral infections and lesions with taxane compounds |
| JP2004511510A (ja) * | 2000-10-16 | 2004-04-15 | ネオファーム、インコーポレイティッド | ミトキサントロンのリポソーム製剤 |
| CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| US7341985B2 (en) * | 2004-10-08 | 2008-03-11 | Air Products And Chemicals, Inc. | 2-Hydroxy-3-alkoxypropyl sulfides, sulfones, and sulfoxides: new surface active agents |
| WO2009129395A1 (en) * | 2008-04-16 | 2009-10-22 | Abbott Laboratories | Cationic lipids and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4857511A (en) * | 1985-09-17 | 1989-08-15 | Burroughs Wellcome Co. | Treatment of human viral infections |
| DE3638126A1 (de) * | 1986-11-08 | 1988-05-11 | Nattermann A & Cie | Mercaptoalkanolphospholipide und deren derivate, verfahren zu ihrer herstellung und ihre verwendung als wirkstoffe in arzneimitteln |
| US4997851A (en) * | 1987-12-31 | 1991-03-05 | Isaacs Charles E | Antiviral and antibacterial activity of fatty acids and monoglycerides |
| DE3929217A1 (de) * | 1989-09-02 | 1991-03-07 | Boehringer Mannheim Gmbh | Verwendung von phospholipid-derivaten als antivirale arzneimittel und neue phospholipide |
| DE3934820A1 (de) * | 1989-10-19 | 1991-04-25 | Boehringer Mannheim Gmbh | Verwendung von lecithin-analoga als antivirale arzneimittel und neue derivate |
-
1995
- 1995-10-14 DE DE19538402A patent/DE19538402A1/de not_active Withdrawn
-
1996
- 1996-10-11 JP JP9515499A patent/JPH11513677A/ja not_active Ceased
- 1996-10-11 AU AU72912/96A patent/AU722835B2/en not_active Ceased
- 1996-10-11 IL IL12391596A patent/IL123915A/xx not_active IP Right Cessation
- 1996-10-11 PT PT96934651T patent/PT854708E/pt unknown
- 1996-10-11 WO PCT/EP1996/004438 patent/WO1997014410A1/de not_active Application Discontinuation
- 1996-10-11 HU HU9900725A patent/HUP9900725A3/hu unknown
- 1996-10-11 DE DE59608464T patent/DE59608464D1/de not_active Expired - Fee Related
- 1996-10-11 EP EP96934651A patent/EP0854708B1/de not_active Expired - Lifetime
- 1996-10-11 NZ NZ320211A patent/NZ320211A/xx unknown
- 1996-10-11 AT AT96934651T patent/ATE210434T1/de not_active IP Right Cessation
- 1996-10-11 CA CA002234244A patent/CA2234244A1/en not_active Abandoned
- 1996-10-11 KR KR1019980702727A patent/KR19990064240A/ko not_active Application Discontinuation
- 1996-10-11 ES ES96934651T patent/ES2169816T3/es not_active Expired - Lifetime
- 1996-10-11 ZA ZA9608597A patent/ZA968597B/xx unknown
- 1996-10-11 US US09/051,088 patent/US6177469B1/en not_active Expired - Fee Related
- 1996-10-11 DK DK96934651T patent/DK0854708T3/da active
- 1996-10-14 TW TW085112614A patent/TW426513B/zh not_active IP Right Cessation
-
1998
- 1998-04-08 NO NO981629A patent/NO981629L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0854708A1 (de) | 1998-07-29 |
| DE59608464D1 (de) | 2002-01-24 |
| DE19538402A1 (de) | 1997-04-17 |
| EP0854708B1 (de) | 2001-12-12 |
| US6177469B1 (en) | 2001-01-23 |
| NO981629D0 (no) | 1998-04-08 |
| IL123915A (en) | 2003-01-12 |
| HUP9900725A2 (hu) | 1999-06-28 |
| WO1997014410A1 (de) | 1997-04-24 |
| AU722835B2 (en) | 2000-08-10 |
| ES2169816T3 (es) | 2002-07-16 |
| JPH11513677A (ja) | 1999-11-24 |
| AU7291296A (en) | 1997-05-07 |
| HUP9900725A3 (en) | 2001-08-28 |
| DK0854708T3 (da) | 2002-04-08 |
| PT854708E (pt) | 2002-06-28 |
| KR19990064240A (ko) | 1999-07-26 |
| TW426513B (en) | 2001-03-21 |
| ATE210434T1 (de) | 2001-12-15 |
| CA2234244A1 (en) | 1997-04-24 |
| NZ320211A (en) | 2000-01-28 |
| NO981629L (no) | 1998-06-12 |
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