ZA962336B - Reversible protease inhibitors - Google Patents
Reversible protease inhibitorsInfo
- Publication number
- ZA962336B ZA962336B ZA962336A ZA962336A ZA962336B ZA 962336 B ZA962336 B ZA 962336B ZA 962336 A ZA962336 A ZA 962336A ZA 962336 A ZA962336 A ZA 962336A ZA 962336 B ZA962336 B ZA 962336B
- Authority
- ZA
- South Africa
- Prior art keywords
- protease inhibitors
- reversible protease
- reversible
- inhibitors
- protease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/6533—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40999695A | 1995-03-24 | 1995-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA962336B true ZA962336B (en) | 1996-07-31 |
Family
ID=23622800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA962336A ZA962336B (en) | 1995-03-24 | 1996-03-22 | Reversible protease inhibitors |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0817778A1 (en) |
| JP (1) | JPH11503417A (en) |
| KR (1) | KR19980703261A (en) |
| CN (1) | CN1071751C (en) |
| AU (1) | AU713492B2 (en) |
| CA (1) | CA2216151A1 (en) |
| CZ (1) | CZ298197A3 (en) |
| IL (1) | IL117638A0 (en) |
| MY (1) | MY113489A (en) |
| NO (1) | NO311573B1 (en) |
| NZ (1) | NZ305626A (en) |
| PL (1) | PL322409A1 (en) |
| TW (1) | TW470750B (en) |
| WO (1) | WO1996030353A1 (en) |
| ZA (1) | ZA962336B (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997040066A1 (en) | 1996-04-22 | 1997-10-30 | Massachusetts Institute Of Technology | Suppression of immune response via inhibition of cathepsin s |
| SK8599A3 (en) * | 1996-07-30 | 2000-03-13 | Arris Pharm Corp | Disubstituted cyclic compound, process for its preparation, pharmaceutical composition and method of the treatment of an animal |
| DE19817461A1 (en) | 1998-04-20 | 1999-10-21 | Basf Ag | New benzamide derivatives useful as cysteine protease inhibitors for treating neurodegenerative diseases, neuronal damage, stroke, cranial trauma, Alzheimer's disease, etc. |
| JP2002538151A (en) | 1999-03-02 | 2002-11-12 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | Compounds useful as reversible inhibitors of cathepsin |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| DK1218372T3 (en) * | 1999-09-13 | 2003-10-20 | Boehringer Ingelheim Pharma | Novel heterocyclic compounds useful as reversible inhibitors of cysteine proteases |
| EP1230349B1 (en) | 1999-11-18 | 2007-06-13 | Dendreon Corporation | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
| US7700341B2 (en) | 2000-02-03 | 2010-04-20 | Dendreon Corporation | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
| JP4911864B2 (en) | 2000-08-14 | 2012-04-04 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | Substituted pyrazoles |
| AU8645401A (en) | 2000-08-14 | 2002-02-25 | Ortho Mcneil Pharm Inc | Substituted pyrazoles |
| US7332494B2 (en) | 2000-08-14 | 2008-02-19 | Janssen Pharmaceutica, N.V. | Method for treating allergies using substituted pyrazoles |
| JP5140225B2 (en) | 2000-08-14 | 2013-02-06 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | Substituted pyrazoles |
| RU2003106192A (en) | 2000-09-06 | 2004-07-27 | Орто-Макнейл Фармасьютикал, Инк. (Us) | METHOD FOR TREATING ALLERGIES |
| WO2002048097A1 (en) * | 2000-12-12 | 2002-06-20 | Corvas International, Inc. | Compounds, compositions and methods for treatment of parasitic infections |
| JP2004523506A (en) | 2000-12-22 | 2004-08-05 | アクシス・ファーマシューティカルズ・インコーポレイテッド | Novel compounds and compositions as cathepsin inhibitors |
| US7030116B2 (en) | 2000-12-22 | 2006-04-18 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin inhibitors |
| US6900237B2 (en) | 2001-09-14 | 2005-05-31 | Axys Pharmaceuticals, Inc. | Sulfonamide compounds as protease inhibitors |
| PL369312A1 (en) * | 2001-09-14 | 2005-04-18 | Aventis Pharmaceuticals Inc. | Novel compounds and compositions as cathepsin inhibitors |
| YU34604A (en) | 2001-11-14 | 2006-08-17 | Aventis Pharmaceuticals Inc. | Oligopeptides and compositions containing them as cathepsin s inhibitors |
| GB0311406D0 (en) * | 2003-05-17 | 2003-06-25 | Queen Mary & Westfield College | Substituted phosphonate fluorescent sensors,and use thereof |
| AU2009250295B2 (en) | 2008-05-21 | 2014-05-01 | Genesis Technologies Limited | Selective caspase inhibitors and uses thereof |
| US9045524B2 (en) | 2009-05-21 | 2015-06-02 | Novagenesis Foundation | Selective caspase inhibitors and uses thereof |
| US8895497B2 (en) | 2009-12-04 | 2014-11-25 | Dcb-Usa, Llc | Cathepsin S inhibitors |
| EP2697246B1 (en) | 2011-04-15 | 2018-03-07 | Genesis Technologies Limited | Selective cysteine protease inhibitors and uses thereof |
| KR101309578B1 (en) * | 2011-05-06 | 2013-09-17 | 연세대학교 산학협력단 | Dityrosine compounds having selectivity for cysteine proteases and method for monitoring cysteine proteases using the same |
| KR101385855B1 (en) * | 2012-10-16 | 2014-04-22 | 이동익 | Diaromatic amino acid-based substrate for detecting cathepsins |
| WO2019142890A1 (en) * | 2018-01-19 | 2019-07-25 | 株式会社大阪ソーダ | Organosilicon compound and rubber composition including same |
| EP3553521A1 (en) * | 2018-04-12 | 2019-10-16 | Koninklijke Philips N.V. | Gingivitis diagnostic methods, uses and kits |
-
1996
- 1996-03-21 CN CN96193951A patent/CN1071751C/en not_active Expired - Fee Related
- 1996-03-21 WO PCT/US1996/003844 patent/WO1996030353A1/en not_active Application Discontinuation
- 1996-03-21 CZ CZ972981A patent/CZ298197A3/en unknown
- 1996-03-21 PL PL96322409A patent/PL322409A1/en unknown
- 1996-03-21 NZ NZ305626A patent/NZ305626A/en unknown
- 1996-03-21 AU AU53674/96A patent/AU713492B2/en not_active Ceased
- 1996-03-21 CA CA002216151A patent/CA2216151A1/en not_active Abandoned
- 1996-03-21 EP EP96910499A patent/EP0817778A1/en not_active Withdrawn
- 1996-03-21 JP JP8529509A patent/JPH11503417A/en active Pending
- 1996-03-21 KR KR1019970706665A patent/KR19980703261A/en not_active Application Discontinuation
- 1996-03-22 MY MYPI96001076A patent/MY113489A/en unknown
- 1996-03-22 ZA ZA962336A patent/ZA962336B/en unknown
- 1996-03-24 IL IL11763896A patent/IL117638A0/en unknown
- 1996-04-12 TW TW085104392A patent/TW470750B/en active
-
1997
- 1997-09-23 NO NO19974403A patent/NO311573B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996030353A1 (en) | 1996-10-03 |
| AU5367496A (en) | 1996-10-16 |
| TW470750B (en) | 2002-01-01 |
| CA2216151A1 (en) | 1996-10-03 |
| NO974403D0 (en) | 1997-09-23 |
| JPH11503417A (en) | 1999-03-26 |
| MY113489A (en) | 2002-03-30 |
| CZ298197A3 (en) | 1998-03-18 |
| EP0817778A1 (en) | 1998-01-14 |
| KR19980703261A (en) | 1998-10-15 |
| IL117638A0 (en) | 1996-07-23 |
| NO311573B1 (en) | 2001-12-10 |
| NO974403L (en) | 1997-11-17 |
| NZ305626A (en) | 2000-01-28 |
| CN1184472A (en) | 1998-06-10 |
| AU713492B2 (en) | 1999-12-02 |
| CN1071751C (en) | 2001-09-26 |
| PL322409A1 (en) | 1998-01-19 |
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