ZA951653B - Ureido derivatives of naphthalenephosphonic acids and process for their preparation - Google Patents

Ureido derivatives of naphthalenephosphonic acids and process for their preparation

Info

Publication number
ZA951653B
ZA951653B ZA951653A ZA951653A ZA951653B ZA 951653 B ZA951653 B ZA 951653B ZA 951653 A ZA951653 A ZA 951653A ZA 951653 A ZA951653 A ZA 951653A ZA 951653 B ZA951653 B ZA 951653B
Authority
ZA
South Africa
Prior art keywords
pct
same
preparation
ureido derivatives
naphthalenephosphonic
Prior art date
Application number
ZA951653A
Other languages
English (en)
Inventor
Nicola Mongelli
Angelo Crugnola
Andrea Lombardi Borgia
Enrico Pesenti
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of ZA951653B publication Critical patent/ZA951653B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
ZA951653A 1994-03-01 1995-02-28 Ureido derivatives of naphthalenephosphonic acids and process for their preparation ZA951653B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9403909A GB9403909D0 (en) 1994-03-01 1994-03-01 Ureido derivatives of naphthalenephosphonic acids and process for their preparation

Publications (1)

Publication Number Publication Date
ZA951653B true ZA951653B (en) 1995-12-08

Family

ID=10751089

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA951653A ZA951653B (en) 1994-03-01 1995-02-28 Ureido derivatives of naphthalenephosphonic acids and process for their preparation

Country Status (26)

Country Link
US (1) US5700788A (xx)
EP (1) EP0696287B1 (xx)
JP (1) JPH08509992A (xx)
KR (1) KR960701881A (xx)
CN (1) CN1061050C (xx)
AT (1) ATE190312T1 (xx)
AU (1) AU678704B2 (xx)
CA (1) CA2160250A1 (xx)
DE (1) DE69515390T2 (xx)
DK (1) DK0696287T3 (xx)
ES (1) ES2145268T3 (xx)
FI (1) FI955180A0 (xx)
GB (1) GB9403909D0 (xx)
GR (1) GR3033356T3 (xx)
HU (1) HUT74987A (xx)
IL (1) IL112716A0 (xx)
MX (1) MX9504381A (xx)
MY (1) MY130125A (xx)
NO (1) NO308005B1 (xx)
NZ (1) NZ281205A (xx)
PL (1) PL311339A1 (xx)
PT (1) PT696287E (xx)
RU (1) RU2136692C1 (xx)
TW (1) TW290547B (xx)
WO (1) WO1995023806A2 (xx)
ZA (1) ZA951653B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2064915C (en) * 1989-08-07 2001-05-29 Deborah A. Rathjen Tumour necrosis factor binding ligands
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
US20030225254A1 (en) * 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
US20040120952A1 (en) * 2000-08-07 2004-06-24 Centocor, Inc Anti-TNF antibodies and peptides of human tumor necrosis factor
US7192584B2 (en) 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
US6284471B1 (en) * 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
US6277969B1 (en) * 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US20050260201A1 (en) * 1993-01-29 2005-11-24 Centocor, Inc. Methods of treating rheumatoid arthritis using anti-TNF receptor fusion proteins
GB9504065D0 (en) * 1995-03-01 1995-04-19 Pharmacia Spa Poly-pyrrolecarboxamidonaphthalenic acid derivatives
FR2736914B1 (fr) * 1995-07-21 1997-08-22 Adir Nouveaux derives d'acide aminophenylphosphonique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB2310207A (en) * 1996-02-15 1997-08-20 Pharmacia Spa Antiviral ureido derivatives of substituted heterocyclic compounds
FR2758562B1 (fr) * 1997-01-20 1999-02-19 Adir Nouveaux derives d'acides mixtes aminobenzyliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2758560B1 (fr) * 1997-01-20 2000-02-04 Adir Nouveaux derives d'acides aminophenylboronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9713732D0 (en) * 1997-06-27 1997-09-03 Pharmacia & Upjohn Spa Substituted triazinic compounds
GB9713733D0 (en) * 1997-06-27 1997-09-03 Pharmacia & Upjohn Spa Poly-branched polycarboxamido compounds
WO1999005148A1 (en) * 1997-07-24 1999-02-04 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
US6096730A (en) * 1997-07-24 2000-08-01 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
AU1711499A (en) 1997-12-04 1999-06-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Ureido derivatives of poly-4-amino-2-carboxy-1-methyl pyrrole compounds or inhibition of inflammation
US6395718B1 (en) 1998-07-06 2002-05-28 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of inhibiting angiogenesis using naaladase inhibitors
AU770258B2 (en) 1998-07-06 2004-02-19 Eisai Inc. Naaladase inhibitors useful as pharmaceutical compounds and compositions
PT1159003E (pt) * 1999-03-02 2011-02-22 Centocor Inc Anti-tnf alfa na terapêutica da asma resistente a esteróides
US6348464B1 (en) 1999-11-12 2002-02-19 Guilford Pharmaceuticals, Inc. Pyrrolecarbonylimino derivatives as naaladase inhibitors
US20050249735A1 (en) * 2000-08-07 2005-11-10 Centocor, Inc. Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
US20110195063A1 (en) * 2000-08-07 2011-08-11 Centocor, Inc. Methods of Treating Ankylosing Spondylitis Using Anti-TNF Antibodies and Peptides of Human Tumor Necrosis Factor
US20060018907A1 (en) * 2000-08-07 2006-01-26 Centocor, Inc. Anti-TNF antibodies and peptides of human tumor necrosis factor
TWI327597B (en) * 2001-08-01 2010-07-21 Centocor Inc Anti-tnf antibodies, compositions, methods and uses
US20090038182A1 (en) * 2007-08-09 2009-02-12 Lans Maris J Footwear with built-in scale
US10465003B2 (en) 2016-02-05 2019-11-05 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
EP3381897A1 (en) 2017-03-27 2018-10-03 Leadiant Biosciences SA Derivatives of the disodium 2,2'-{carbonylbis[imino-3,1-phenylenecarbonylimino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino]}dinaphthalene-1,5-disulfonate salt and related compounds as heparanase inhibitors for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310752A (en) * 1986-05-20 1994-05-10 Farmitalia Carlo Erba Spa Site specific alkylating agents
CA1308516C (en) * 1987-07-06 1992-10-06 J. William Lown Oligopeptide anticancer and antiviral agents
GB9000644D0 (en) * 1990-01-11 1990-03-14 Erba Carlo Spa New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
IT1247878B (it) * 1991-02-15 1995-01-05 Menarini Farma Ind Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB9304589D0 (en) * 1993-03-05 1993-04-21 Erba Carlo Spa Biologically active ureido derivatives useful as antimetastic agents

Also Published As

Publication number Publication date
IL112716A0 (en) 1995-05-26
US5700788A (en) 1997-12-23
WO1995023806A3 (en) 1995-09-28
HU9503433D0 (en) 1996-01-29
ES2145268T3 (es) 2000-07-01
PT696287E (pt) 2000-08-31
NO954346L (no) 1995-10-30
DE69515390T2 (de) 2000-09-21
FI955180A (fi) 1995-10-30
DE69515390D1 (de) 2000-04-13
PL311339A1 (en) 1996-02-05
AU1848895A (en) 1995-09-18
NZ281205A (en) 1997-01-29
GR3033356T3 (en) 2000-09-29
DK0696287T3 (da) 2000-07-31
MX9504381A (es) 1997-01-31
GB9403909D0 (en) 1994-04-20
KR960701881A (ko) 1996-03-28
CA2160250A1 (en) 1995-09-08
NO308005B1 (no) 2000-07-03
WO1995023806A2 (en) 1995-09-08
FI955180A0 (fi) 1995-10-30
EP0696287B1 (en) 2000-03-08
EP0696287A1 (en) 1996-02-14
ATE190312T1 (de) 2000-03-15
MY130125A (en) 2007-06-29
JPH08509992A (ja) 1996-10-22
RU2136692C1 (ru) 1999-09-10
CN1124027A (zh) 1996-06-05
AU678704B2 (en) 1997-06-05
CN1061050C (zh) 2001-01-24
HUT74987A (en) 1997-03-28
TW290547B (xx) 1996-11-11
NO954346D0 (no) 1995-10-30

Similar Documents

Publication Publication Date Title
GR3033356T3 (en) Ureido derivatives of naphthalenephosphonic acids and process for their preparation
AU677852B2 (en) Acetamide derivatives and their use for modifying feeding behavior modifiers
CA2075876A1 (fr) Nouveaux derives d'arylethylamines, leurs procedes de preparation et lescompositions pharmaceutiques qui les contiennent
ZA951227B (en) Camptothecin derivatives and process for their preparation
CA2238845A1 (fr) Nouveaux derives de 2,3,5-trimethyl-4-hydroxy anilides, leur preparation et leur application en therapeutique
NO972623D0 (no) Framasöytisk blanding omfattende lamotrigin
AU1812795A (en) Novel amino acid derivatives, method of producing them and pharmaceutical compositions containing these compounds
CA2127067A1 (fr) Derives d'acide phosphonique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU5644296A (en) Novel heterocyclic chemistry
AU7582396A (en) Synthesis of carboxylic acid derivatives
ES2049186A1 (es) Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol.
DE69417907D1 (de) Anthracyclin-disaccharide, verfahren zu ihrer herstellung, und diese enthaltende arzneimittel
MX9707673A (es) Derivados de ureido biologicamente activos, eficaces en el tratamiento de la esclerosis multiple.