ZA949050B - Cyclic amino acid derivatives - Google Patents

Cyclic amino acid derivatives

Info

Publication number
ZA949050B
ZA949050B ZA949050A ZA949050A ZA949050B ZA 949050 B ZA949050 B ZA 949050B ZA 949050 A ZA949050 A ZA 949050A ZA 949050 A ZA949050 A ZA 949050A ZA 949050 B ZA949050 B ZA 949050B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
cyclic amino
cyclic
derivatives
Prior art date
Application number
ZA949050A
Other languages
English (en)
Inventor
Cynthia Anne Fink
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA949050B publication Critical patent/ZA949050B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/38Amides of thiocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA949050A 1993-11-16 1994-11-15 Cyclic amino acid derivatives ZA949050B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/153,395 US5432186A (en) 1993-11-16 1993-11-16 Cyclic amino acid derivatives

Publications (1)

Publication Number Publication Date
ZA949050B true ZA949050B (en) 1995-08-11

Family

ID=22547049

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA949050A ZA949050B (en) 1993-11-16 1994-11-15 Cyclic amino acid derivatives

Country Status (5)

Country Link
US (2) US5432186A (cs)
KR (1) KR100432618B1 (cs)
SA (1) SA95160293B1 (cs)
TW (1) TW267154B (cs)
ZA (1) ZA949050B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034136A (en) * 1997-03-20 2000-03-07 Novartis Ag Certain cyclic thio substituted acylaminoacid amide derivatives
US6291511B1 (en) 1997-05-29 2001-09-18 Merck & Co., Inc. Biarylalkanoic acids as cell adhesion inhibitors
MY153569A (en) * 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
EP1080104B1 (en) * 1998-04-23 2005-02-09 Novartis AG Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
US6423727B1 (en) * 1998-04-23 2002-07-23 Novartis Ag Certain thiol inhibitors of endothelin-converting enzyme
US6426354B1 (en) 1998-04-23 2002-07-30 Novartis Ag Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
JP2002542151A (ja) * 1999-02-18 2002-12-10 科研製薬株式会社 成長ホルモン分泌促進物質としての新規なアミド誘導体
CA2385882C (en) * 1999-09-24 2009-11-24 Genentech, Inc. Tyrosine derivatives
KR100622436B1 (ko) * 1999-12-18 2006-09-11 삼성토탈 주식회사 노보렌 이성질체의 분리방법
US6777443B2 (en) * 2001-05-15 2004-08-17 Novartis Ag Dipeptide derivatives
BR0212899A (pt) * 2001-09-21 2004-11-03 Novartis Ag Compostos orgânicos
MY140707A (en) * 2002-02-28 2010-01-15 Mitsubishi Tanabe Pharma Corp Process for preparing a phenylalanine derivative and intermediates thereof
KR20110004472A (ko) * 2008-05-07 2011-01-13 노파르티스 아게 알파-머캅토-아미드
CN102076688A (zh) * 2008-05-15 2011-05-25 诺瓦提斯公司 作为中性内肽酶抑制剂的另外包含巯基-酰基氨基的嘌呤衍生物
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093739A (en) * 1977-06-15 1978-06-06 Mead Johnson & Company Mercaptoacylamidobenzoyl glycine and mucolytic process
GB9004260D0 (en) * 1990-02-26 1990-04-18 Pfizer Ltd Therapeutic agents
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
US5208236A (en) * 1992-09-23 1993-05-04 Schering Corporation N-(acylaminomethyl)glutaryl amino acids and use

Also Published As

Publication number Publication date
TW267154B (cs) 1996-01-01
SA95160293B1 (ar) 2005-02-09
US5432186A (en) 1995-07-11
US5506244A (en) 1996-04-09
KR100432618B1 (ko) 2004-08-31
KR950014064A (ko) 1995-06-15

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