ZA945032B - Pyrimidones and imidazolinones for treatment of shock - Google Patents
Pyrimidones and imidazolinones for treatment of shockInfo
- Publication number
- ZA945032B ZA945032B ZA945032A ZA945032A ZA945032B ZA 945032 B ZA945032 B ZA 945032B ZA 945032 A ZA945032 A ZA 945032A ZA 945032 A ZA945032 A ZA 945032A ZA 945032 B ZA945032 B ZA 945032B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrimidones
- imidazolinones
- shock
- treatment
- Prior art date
Links
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical class O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 title 1
- 150000008318 pyrimidones Chemical class 0.000 title 1
- 230000035939 shock Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/091,693 US5482944A (en) | 1993-07-13 | 1993-07-13 | Pyrimidones and imidazolinones for treatment of shock |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA945032B true ZA945032B (en) | 1996-01-12 |
Family
ID=22229174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA945032A ZA945032B (en) | 1993-07-13 | 1994-07-12 | Pyrimidones and imidazolinones for treatment of shock |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5482944A (hu) |
| EP (1) | EP0636369A1 (hu) |
| JP (1) | JP2899861B2 (hu) |
| KR (1) | KR950002763A (hu) |
| CN (1) | CN1105858A (hu) |
| AU (1) | AU6741294A (hu) |
| CA (1) | CA2127735A1 (hu) |
| HU (1) | HUT67598A (hu) |
| IL (1) | IL110243A0 (hu) |
| MX (1) | MX9405318A (hu) |
| RU (1) | RU94026088A (hu) |
| ZA (1) | ZA945032B (hu) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5563143A (en) * | 1994-09-21 | 1996-10-08 | Pfizer Inc. | Catechol diether compounds as inhibitors of TNF release |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3315797A1 (de) * | 1983-04-30 | 1984-10-31 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenyl-2-(1h)-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
| US4971959A (en) * | 1987-04-14 | 1990-11-20 | Warner-Lambert Company | Trisubstituted phenyl analogs having activity for congestive heart failure |
| WO1991007177A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders |
| RU2104306C1 (ru) * | 1989-11-13 | 1998-02-10 | Пфайзер Инк. | Способ получения оптически активного (2s)- или (2r)-эндо-бицикло[2.2.1]гептан-2-ола, способ получения 5-(3-[(2r)-экзо-бицикло[2.2.1]гепт-2-илокси]-4-метоксифенил)-3,4,5,6-тетрагидропиримидин-2(1н)-она, оптически активный 5-(3-[экзо-бицикло[2.2.1]гепт-2-илокси]4-метоксифенил)-3,4,5,6-тетрагидропиримидин-2(1н)-он, оптически активные промежуточные соединения и способ их получения |
| CA2095429A1 (en) * | 1990-11-06 | 1992-05-07 | Paul E. Bender | Imidazolidinone compounds |
-
1993
- 1993-07-13 US US08/091,693 patent/US5482944A/en not_active Expired - Fee Related
-
1994
- 1994-06-28 EP EP94304733A patent/EP0636369A1/en not_active Withdrawn
- 1994-07-05 JP JP6174895A patent/JP2899861B2/ja not_active Expired - Lifetime
- 1994-07-07 IL IL11024394A patent/IL110243A0/xx unknown
- 1994-07-11 CA CA002127735A patent/CA2127735A1/en not_active Abandoned
- 1994-07-12 ZA ZA945032A patent/ZA945032B/xx unknown
- 1994-07-12 HU HU9402081A patent/HUT67598A/hu unknown
- 1994-07-12 MX MX9405318A patent/MX9405318A/es unknown
- 1994-07-12 AU AU67412/94A patent/AU6741294A/en not_active Abandoned
- 1994-07-12 KR KR1019940016686A patent/KR950002763A/ko not_active Application Discontinuation
- 1994-07-12 RU RU94026088/14A patent/RU94026088A/ru unknown
- 1994-07-13 CN CN94108290A patent/CN1105858A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR950002763A (ko) | 1995-02-16 |
| CA2127735A1 (en) | 1995-01-14 |
| RU94026088A (ru) | 1996-05-20 |
| MX9405318A (es) | 1995-01-31 |
| AU6741294A (en) | 1995-01-27 |
| HUT67598A (en) | 1995-04-28 |
| CN1105858A (zh) | 1995-08-02 |
| EP0636369A1 (en) | 1995-02-01 |
| HU9402081D0 (en) | 1994-09-28 |
| JP2899861B2 (ja) | 1999-06-02 |
| JPH08208473A (ja) | 1996-08-13 |
| US5482944A (en) | 1996-01-09 |
| IL110243A0 (en) | 1994-10-21 |
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