ZA938836B - Use of inhibitors of ornithine aminotransferase in the treatment of dementia of the alzheimer's type - Google Patents

Use of inhibitors of ornithine aminotransferase in the treatment of dementia of the alzheimer's type

Info

Publication number
ZA938836B
ZA938836B ZA938836A ZA938836A ZA938836B ZA 938836 B ZA938836 B ZA 938836B ZA 938836 A ZA938836 A ZA 938836A ZA 938836 A ZA938836 A ZA 938836A ZA 938836 B ZA938836 B ZA 938836B
Authority
ZA
South Africa
Prior art keywords
dementia
alzheimer
inhibitors
treatment
type
Prior art date
Application number
ZA938836A
Other languages
English (en)
Inventor
Nikolaus Seiler
Jean-Bernard Ducep
Karin C Jund
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA938836B publication Critical patent/ZA938836B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA938836A 1993-02-05 1993-11-25 Use of inhibitors of ornithine aminotransferase in the treatment of dementia of the alzheimer's type ZA938836B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93400303A EP0609630A1 (en) 1993-02-05 1993-02-05 Use of inhibitors of ornithine aminotransferase for the manufacture of a medicament for the treatment of Alzheimer's disease

Publications (1)

Publication Number Publication Date
ZA938836B true ZA938836B (en) 1994-08-02

Family

ID=8214677

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938836A ZA938836B (en) 1993-02-05 1993-11-25 Use of inhibitors of ornithine aminotransferase in the treatment of dementia of the alzheimer's type

Country Status (14)

Country Link
US (1) US5637768A (no)
EP (2) EP0609630A1 (no)
JP (1) JPH08506577A (no)
AU (1) AU682330B2 (no)
CA (1) CA2152796A1 (no)
FI (1) FI953725A (no)
HU (1) HUT73173A (no)
IL (1) IL107737A (no)
MX (1) MX9400911A (no)
NO (1) NO953072L (no)
NZ (2) NZ258461A (no)
TW (1) TW383337B (no)
WO (1) WO1994017795A1 (no)
ZA (1) ZA938836B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1448183A2 (en) * 2001-11-16 2004-08-25 ALS Therapy Development Foundation, Inc. Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
US7273888B2 (en) * 2001-11-16 2007-09-25 Als Therapy Development Foundation, Inc. Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
CN111362828A (zh) * 2020-03-30 2020-07-03 山西医科大学 一种18f标记的氟丙酰化鸟氨酸及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE77367T1 (de) * 1988-02-05 1992-07-15 Merrell Dow Pharma 5-substituierte ornithin-derivate.

Also Published As

Publication number Publication date
HU9502320D0 (en) 1996-05-28
NZ280983A (en) 1997-07-27
US5637768A (en) 1997-06-10
JPH08506577A (ja) 1996-07-16
IL107737A0 (en) 1994-02-27
CA2152796A1 (en) 1994-08-18
NO953072D0 (no) 1995-08-04
AU682330B2 (en) 1997-10-02
EP0682515A1 (en) 1995-11-22
NO953072L (no) 1995-08-04
FI953725A0 (fi) 1995-08-04
IL107737A (en) 1998-12-27
AU5614394A (en) 1994-08-29
FI953725A (fi) 1995-08-04
WO1994017795A1 (en) 1994-08-18
NZ258461A (en) 1997-03-24
TW383337B (en) 2000-03-01
MX9400911A (es) 1994-08-31
HUT73173A (en) 1996-06-28
EP0609630A1 (en) 1994-08-10

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