ZA938709B - Multifunctional neurotrophic factors - Google Patents

Multifunctional neurotrophic factors

Info

Publication number
ZA938709B
ZA938709B ZA938709A ZA938709A ZA938709B ZA 938709 B ZA938709 B ZA 938709B ZA 938709 A ZA938709 A ZA 938709A ZA 938709 A ZA938709 A ZA 938709A ZA 938709 B ZA938709 B ZA 938709B
Authority
ZA
South Africa
Prior art keywords
multifunctional
neurotrophic factors
neurotrophins
neurotrophic
factors
Prior art date
Application number
ZA938709A
Other languages
English (en)
Inventor
Moliner Carlos Fernando Ibanez
Hakan Bengt Persson
Original Assignee
Moliner Carlos Fernando Ibanez
Mcintyre Katherine Rowe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moliner Carlos Fernando Ibanez, Mcintyre Katherine Rowe filed Critical Moliner Carlos Fernando Ibanez
Publication of ZA938709B publication Critical patent/ZA938709B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
ZA938709A 1992-11-20 1993-11-22 Multifunctional neurotrophic factors ZA938709B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/979,630 US5488099A (en) 1992-03-06 1992-11-20 Multifunctional chimeric neurotrophic factors

Publications (1)

Publication Number Publication Date
ZA938709B true ZA938709B (en) 1994-08-05

Family

ID=25527026

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938709A ZA938709B (en) 1992-11-20 1993-11-22 Multifunctional neurotrophic factors

Country Status (10)

Country Link
US (2) US5488099A (xx)
EP (1) EP0674660B1 (xx)
JP (1) JPH08504405A (xx)
AT (1) ATE179181T1 (xx)
AU (1) AU677979B2 (xx)
CA (1) CA2149862A1 (xx)
DE (1) DE69324601T2 (xx)
IL (1) IL107674A0 (xx)
WO (1) WO1994012539A1 (xx)
ZA (1) ZA938709B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573904B1 (en) * 1992-06-08 2001-09-26 Takeda Chemical Industries, Ltd. Therapeutic agent for neutropenia
IL109280A0 (en) * 1993-04-15 1994-07-31 Regeneron Pharma Neurotrophins for treatment of depression
US5728803A (en) * 1994-06-03 1998-03-17 Genentech, Inc. Pantropic neurotrophic factors
US7144983B1 (en) 1997-02-03 2006-12-05 Genentech, Inc. Pantropic neurotrophic factors
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US5958875A (en) * 1996-03-29 1999-09-28 The Regents Of The University Of California Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity
HU222666B1 (hu) 1996-11-15 2003-09-29 Genentech, Inc. Eljárás neuorotrofinok tisztítására
US6663899B2 (en) * 1997-06-13 2003-12-16 Genentech, Inc. Controlled release microencapsulated NGF formulation
US6113947A (en) * 1997-06-13 2000-09-05 Genentech, Inc. Controlled release microencapsulated NGF formulation
CA2212315A1 (en) * 1997-08-05 1999-02-05 Mcgill University Pharmaceutical composition with neurotrophic-like biological activity
ATE406907T1 (de) * 1998-10-28 2008-09-15 Cornell Res Foundation Inc Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4
ES2315842T3 (es) * 2004-01-19 2009-04-01 Nsgene A/S Celulas terapeuticas humanas que secretan factor de crecimiento nervioso.
EP2594295A1 (en) 2011-11-16 2013-05-22 Servicio Andaluz De Salud Nerve implants based on a compacted biomaterial containing cells
CN115942951A (zh) * 2020-07-27 2023-04-07 人类细胞公司 Ngf变体，制备，组合物和治疗用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235043A (en) * 1990-04-06 1993-08-10 Synergen, Inc. Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins

Also Published As

Publication number Publication date
EP0674660B1 (en) 1999-04-21
DE69324601D1 (de) 1999-05-27
US5889173A (en) 1999-03-30
WO1994012539A1 (en) 1994-06-09
CA2149862A1 (en) 1994-06-09
JPH08504405A (ja) 1996-05-14
EP0674660A1 (en) 1995-10-04
AU5614894A (en) 1994-06-22
ATE179181T1 (de) 1999-05-15
IL107674A0 (en) 1994-02-27
DE69324601T2 (de) 1999-12-02
AU677979B2 (en) 1997-05-15
US5488099A (en) 1996-01-30

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