ZA934780B - A process for recovering a recombinant protein in biologically active from a solution containing inactive protein - Google Patents
A process for recovering a recombinant protein in biologically active from a solution containing inactive proteinInfo
- Publication number
- ZA934780B ZA934780B ZA934780A ZA934780A ZA934780B ZA 934780 B ZA934780 B ZA 934780B ZA 934780 A ZA934780 A ZA 934780A ZA 934780 A ZA934780 A ZA 934780A ZA 934780 B ZA934780 B ZA 934780B
- Authority
- ZA
- South Africa
- Prior art keywords
- protein
- recovering
- solution containing
- biologically active
- containing inactive
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90814692A | 1992-07-02 | 1992-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA934780B true ZA934780B (en) | 1994-03-17 |
Family
ID=25425274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA934780A ZA934780B (en) | 1992-07-02 | 1993-07-02 | A process for recovering a recombinant protein in biologically active from a solution containing inactive protein |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0650497A1 (OSRAM) |
| CN (1) | CN1039330C (OSRAM) |
| AU (1) | AU4665193A (OSRAM) |
| PL (1) | PL306858A1 (OSRAM) |
| TW (1) | TW235965B (OSRAM) |
| WO (1) | WO1994001453A1 (OSRAM) |
| ZA (1) | ZA934780B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7270809B2 (en) | 1997-07-14 | 2007-09-18 | Bolder Biotechnology, Inc. | Cysteine variants of alpha interferon-2 |
| US6753165B1 (en) | 1999-01-14 | 2004-06-22 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
| US20080076706A1 (en) | 1997-07-14 | 2008-03-27 | Bolder Biotechnology, Inc. | Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof |
| NZ502375A (en) | 1997-07-14 | 2001-11-30 | Bolder Biotechnology Inc | The addition of non-natural cysteine derivatives to cause the protein to act as antagonists of the GH family |
| US7153943B2 (en) | 1997-07-14 | 2006-12-26 | Bolder Biotechnology, Inc. | Derivatives of growth hormone and related proteins, and methods of use thereof |
| WO2001087925A2 (en) * | 2000-05-16 | 2001-11-22 | Bolder Biotechnology, Inc. | Methods for refolding proteins containing free cysteine residues |
| WO2000012537A1 (en) * | 1998-08-27 | 2000-03-09 | Lg Chemical Limited | Process for the preparation of active somatotropin from inclusion bodies |
| US8288126B2 (en) | 1999-01-14 | 2012-10-16 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
| WO2008076933A2 (en) | 2006-12-14 | 2008-06-26 | Bolder Biotechnology, Inc. | Long acting proteins and peptides and methods of making and using the same |
| WO2017019776A1 (en) * | 2015-07-27 | 2017-02-02 | Purdue Research Foundation | Tandem folding methods to improve protein folding yield |
| US10745457B2 (en) | 2015-09-02 | 2020-08-18 | Merck Sharp & Dohme Corp. | Process for obtaining insulin with correctly formed disulfide bonds |
| CN111610324B (zh) * | 2020-06-06 | 2022-10-14 | 北京均大检测科技有限公司 | 一种ripa裂解液及其制备方法 |
| CN114878728A (zh) * | 2022-05-06 | 2022-08-09 | 浙江大学 | 一种新型的抗体肽图检测还原方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
| WO1989001046A1 (en) * | 1987-07-29 | 1989-02-09 | Schering Biotech Corporation | Purification of human interleukin-4 expressed in escherichia coli |
| JPH01132598A (ja) * | 1987-10-14 | 1989-05-25 | Pitman Moore Inc | 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法 |
| US5064943A (en) * | 1988-12-16 | 1991-11-12 | American Cyanamid Company | Method for solubilization and naturation of somatotropin |
| WO1992004382A1 (en) * | 1990-09-05 | 1992-03-19 | Bunge (Australia) Pty. Ltd. | Solubilization of proteins in active forms |
-
1993
- 1993-07-01 PL PL93306858A patent/PL306858A1/xx unknown
- 1993-07-01 CN CN93108052A patent/CN1039330C/zh not_active Expired - Fee Related
- 1993-07-01 EP EP93916974A patent/EP0650497A1/en not_active Ceased
- 1993-07-01 AU AU46651/93A patent/AU4665193A/en not_active Abandoned
- 1993-07-01 WO PCT/US1993/006351 patent/WO1994001453A1/en not_active Application Discontinuation
- 1993-07-02 ZA ZA934780A patent/ZA934780B/xx unknown
- 1993-07-02 TW TW082105281A patent/TW235965B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1083071A (zh) | 1994-03-02 |
| TW235965B (OSRAM) | 1994-12-11 |
| WO1994001453A1 (en) | 1994-01-20 |
| PL306858A1 (en) | 1995-04-18 |
| EP0650497A1 (en) | 1995-05-03 |
| AU4665193A (en) | 1994-01-31 |
| CN1039330C (zh) | 1998-07-29 |
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