ZA929768B - 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents. - Google Patents

5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents.

Info

Publication number
ZA929768B
ZA929768B ZA929768A ZA929768A ZA929768B ZA 929768 B ZA929768 B ZA 929768B ZA 929768 A ZA929768 A ZA 929768A ZA 929768 A ZA929768 A ZA 929768A ZA 929768 B ZA929768 B ZA 929768B
Authority
ZA
South Africa
Prior art keywords
protein kinase
inhibiting agents
kinase inhibiting
isoquinolinesulfonamide derivatives
isoquinolinesulfonamide
Prior art date
Application number
ZA929768A
Inventor
Silvio Levi
Gianni Gromo
Tiziana Maoret
Alberto Sala
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of ZA929768B publication Critical patent/ZA929768B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA929768A 1991-12-20 1992-12-17 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents. ZA929768B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI913431A IT1252567B (en) 1991-12-20 1991-12-20 DERIVATIVES OF 5-ISOKINOLINSULPHONAMIDS INHIBITORS OF PROTEIN-KINASES

Publications (1)

Publication Number Publication Date
ZA929768B true ZA929768B (en) 1993-06-14

Family

ID=11361396

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929768A ZA929768B (en) 1991-12-20 1992-12-17 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents.

Country Status (4)

Country Link
AU (1) AU3256193A (en)
IT (1) IT1252567B (en)
WO (1) WO1993013072A1 (en)
ZA (1) ZA929768B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators
TW402591B (en) * 1997-07-11 2000-08-21 Janssen Pharmaceutica Nv Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
WO1999027921A2 (en) * 1997-12-03 1999-06-10 Eisai Co., Ltd. Compositions and methods for modulating the activity of fibroblast growth factor
MY179032A (en) 2004-10-25 2020-10-26 Cancer Research Tech Ltd Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
UY29177A1 (en) 2004-10-25 2006-05-31 Astex Therapeutics Ltd SUBSTITUTED DERIVATIVES OF PURINA, PURINONA AND DEAZAPURINA, COMPOSITIONS THAT CONTAIN METHODS FOR THEIR PREPARATION AND ITS USES
JP5606734B2 (en) 2006-04-25 2014-10-15 アステックス、セラピューティックス、リミテッド Pharmaceutical compounds
WO2010042867A2 (en) * 2008-10-09 2010-04-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Activators of human pyruvate kinase
CN102448951B (en) 2009-04-06 2017-05-10 安吉奥斯医药品有限公司 Therapeutic compositions and related methods of use
ES2619557T3 (en) 2009-05-04 2017-06-26 Agios Pharmaceuticals, Inc. PKM2 activators for use in cancer treatment
PL2448581T3 (en) 2009-06-29 2017-06-30 Agios Pharmaceuticals, Inc. Therapeutic compositions and related methods of use
SG177434A1 (en) 2009-06-29 2012-02-28 Agios Pharmaceuticals Inc Therapeutic compounds and compositions
CN102199122A (en) * 2010-03-23 2011-09-28 范扶民 Homopiperazine derivative and preparation method thereof
AU2011245441B2 (en) 2010-04-29 2014-12-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Activators of human pyruvate kinase
CA2821975A1 (en) 2010-12-17 2012-06-21 Shunqi Yan N-(4-(azetidine-1-carbonyl)phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase m2 pkm2 modulators
ES2569712T3 (en) 2010-12-21 2016-05-12 Agios Pharmaceuticals, Inc. PKM2 bicyclic activators
TWI549947B (en) 2010-12-29 2016-09-21 阿吉歐斯製藥公司 Therapeutic compounds and compositions
PT2704721T (en) 2011-05-03 2018-06-14 Agios Pharmaceuticals Inc Pyruvate kinase activators for use in therapy
WO2016201227A1 (en) 2015-06-11 2016-12-15 Agios Pharmaceuticals, Inc. Methods of using pyruvate kinase activators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456757A (en) * 1981-03-20 1984-06-26 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinolinesulfonyl derivatives and process for the preparation thereof
JPH0667926B2 (en) * 1985-11-12 1994-08-31 旭化成工業株式会社 Cyclic isoquinoline sulfonamide derivative

Also Published As

Publication number Publication date
ITMI913431A1 (en) 1993-06-20
ITMI913431A0 (en) 1991-12-20
AU3256193A (en) 1993-07-28
WO1993013072A1 (en) 1993-07-08
IT1252567B (en) 1995-06-19

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