AU3256193A - 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents - Google Patents

5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents

Info

Publication number
AU3256193A
AU3256193A AU32561/93A AU3256193A AU3256193A AU 3256193 A AU3256193 A AU 3256193A AU 32561/93 A AU32561/93 A AU 32561/93A AU 3256193 A AU3256193 A AU 3256193A AU 3256193 A AU3256193 A AU 3256193A
Authority
AU
Australia
Prior art keywords
protein kinase
inhibiting agents
kinase inhibiting
isoquinolinesulfonamide derivatives
isoquinolinesulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32561/93A
Inventor
Gianni Gromo
Silvio Levi
Tiziana Maoret
Alberto Sala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Italfarmaco SpA
Original Assignee
Italfarmaco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco SpA filed Critical Italfarmaco SpA
Publication of AU3256193A publication Critical patent/AU3256193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU32561/93A 1991-12-20 1992-12-11 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents Abandoned AU3256193A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI913431A IT1252567B (en) 1991-12-20 1991-12-20 DERIVATIVES OF 5-ISOKINOLINSULPHONAMIDS INHIBITORS OF PROTEIN-KINASES
ITMI91A3431 1991-12-20

Publications (1)

Publication Number Publication Date
AU3256193A true AU3256193A (en) 1993-07-28

Family

ID=11361396

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32561/93A Abandoned AU3256193A (en) 1991-12-20 1992-12-11 5-isoquinolinesulfonamide derivatives as protein kinase inhibiting agents

Country Status (4)

Country Link
AU (1) AU3256193A (en)
IT (1) IT1252567B (en)
WO (1) WO1993013072A1 (en)
ZA (1) ZA929768B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators
TW402591B (en) * 1997-07-11 2000-08-21 Janssen Pharmaceutica Nv Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
WO1999027921A2 (en) * 1997-12-03 1999-06-10 Eisai Co., Ltd. Compositions and methods for modulating the activity of fibroblast growth factor
UY29177A1 (en) 2004-10-25 2006-05-31 Astex Therapeutics Ltd SUBSTITUTED DERIVATIVES OF PURINA, PURINONA AND DEAZAPURINA, COMPOSITIONS THAT CONTAIN METHODS FOR THEIR PREPARATION AND ITS USES
MY179032A (en) 2004-10-25 2020-10-26 Cancer Research Tech Ltd Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
WO2007125321A2 (en) 2006-04-25 2007-11-08 Astex Therapeutics Limited Purine and deazapurine derivatives as pharmaceutical compounds
EP2344453B1 (en) * 2008-10-09 2016-12-28 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Activators of human pyruvate kinase
AU2010234526B2 (en) 2009-04-06 2016-07-21 Agios Pharmaceuticals, Inc. Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use
CA2760929C (en) 2009-05-04 2018-01-02 Agios Pharmaceuticals, Inc. Pkm2 activators for use in the treatment of cancer
DK2448581T3 (en) 2009-06-29 2017-03-13 Agios Pharmaceuticals Inc Therapeutic compositions and methods for their applications
TWI598337B (en) 2009-06-29 2017-09-11 阿吉歐斯製藥公司 Therapeutic compounds and compositions
CN102199122A (en) * 2010-03-23 2011-09-28 范扶民 Homopiperazine derivative and preparation method thereof
US20130109672A1 (en) 2010-04-29 2013-05-02 The United States Of America,As Represented By The Secretary, Department Of Health And Human Service Activators of human pyruvate kinase
CA2821975A1 (en) 2010-12-17 2012-06-21 Shunqi Yan N-(4-(azetidine-1-carbonyl)phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase m2 pkm2 modulators
ES2569712T3 (en) 2010-12-21 2016-05-12 Agios Pharmaceuticals, Inc. PKM2 bicyclic activators
TWI549947B (en) 2010-12-29 2016-09-21 阿吉歐斯製藥公司 Therapeutic compounds and compositions
KR101873543B1 (en) 2011-05-03 2018-07-02 아지오스 파마슈티컬스 아이엔씨. Pyruvate kinase activators for use in therapy
MD3307271T2 (en) 2015-06-11 2024-01-31 Agios Pharmaceuticals Inc Methods of using pyruvate kinase activators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456757A (en) * 1981-03-20 1984-06-26 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinolinesulfonyl derivatives and process for the preparation thereof
JPH0667926B2 (en) * 1985-11-12 1994-08-31 旭化成工業株式会社 Cyclic isoquinoline sulfonamide derivative

Also Published As

Publication number Publication date
ITMI913431A0 (en) 1991-12-20
WO1993013072A1 (en) 1993-07-08
ZA929768B (en) 1993-06-14
ITMI913431A1 (en) 1993-06-20
IT1252567B (en) 1995-06-19

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