ZA919196B - New and useful excitatory amino acid antagonist - Google Patents
New and useful excitatory amino acid antagonistInfo
- Publication number
- ZA919196B ZA919196B ZA919196A ZA919196A ZA919196B ZA 919196 B ZA919196 B ZA 919196B ZA 919196 A ZA919196 A ZA 919196A ZA 919196 A ZA919196 A ZA 919196A ZA 919196 B ZA919196 B ZA 919196B
- Authority
- ZA
- South Africa
- Prior art keywords
- amino acid
- excitatory amino
- useful
- new
- acid antagonist
- Prior art date
Links
- 239000003194 amino acid receptor blocking agent Substances 0.000 title abstract 2
- 102000018899 Glutamate Receptors Human genes 0.000 abstract 1
- 108010027915 Glutamate Receptors Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/383—Cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62416890A | 1990-12-07 | 1990-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA919196B true ZA919196B (en) | 1992-09-30 |
Family
ID=24500939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA919196A ZA919196B (en) | 1990-12-07 | 1991-11-20 | New and useful excitatory amino acid antagonist |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0639197B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2721933B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE142220T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2097910A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69121920T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0639197T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2094338T3 (cg-RX-API-DMAC7.html) |
| GR (1) | GR3021881T3 (cg-RX-API-DMAC7.html) |
| IE (1) | IE75735B1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO1992010099A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA919196B (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028213A (en) * | 1998-04-16 | 2000-02-22 | Eastman Chemical Company | Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761405A (en) * | 1987-03-04 | 1988-08-02 | Nova Pharmaceutical Corporation | Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency |
-
1991
- 1991-11-20 ZA ZA919196A patent/ZA919196B/xx unknown
- 1991-12-04 DE DE69121920T patent/DE69121920T2/de not_active Expired - Fee Related
- 1991-12-04 WO PCT/US1991/008834 patent/WO1992010099A1/en not_active Ceased
- 1991-12-04 ES ES92901599T patent/ES2094338T3/es not_active Expired - Lifetime
- 1991-12-04 EP EP92901599A patent/EP0639197B1/en not_active Expired - Lifetime
- 1991-12-04 AT AT92901599T patent/ATE142220T1/de not_active IP Right Cessation
- 1991-12-04 JP JP4502346A patent/JP2721933B2/ja not_active Expired - Lifetime
- 1991-12-04 CA CA002097910A patent/CA2097910A1/en not_active Abandoned
- 1991-12-04 DK DK92901599.8T patent/DK0639197T3/da active
- 1991-12-06 IE IE425691A patent/IE75735B1/en not_active IP Right Cessation
-
1996
- 1996-12-04 GR GR960403296T patent/GR3021881T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0639197T3 (cg-RX-API-DMAC7.html) | 1997-02-24 |
| IE75735B1 (en) | 1997-09-24 |
| EP0639197A1 (en) | 1995-02-22 |
| ATE142220T1 (de) | 1996-09-15 |
| GR3021881T3 (en) | 1997-03-31 |
| EP0639197A4 (en) | 1994-02-21 |
| WO1992010099A1 (en) | 1992-06-25 |
| EP0639197B1 (en) | 1996-09-04 |
| JP2721933B2 (ja) | 1998-03-04 |
| JPH06505966A (ja) | 1994-07-07 |
| IE914256A1 (en) | 1992-06-17 |
| CA2097910A1 (en) | 1992-06-08 |
| DE69121920D1 (de) | 1996-10-10 |
| ES2094338T3 (es) | 1997-01-16 |
| DE69121920T2 (de) | 1997-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA199700260A1 (ru) | Готовая препаративная форма 2-метилтиенобензодиазепина для перорального введения и способ ее получения | |
| NZ236581A (en) | 3-amino piperidine derivatives, analogues and pharmaceutical compositions | |
| KR900012911A (ko) | 흥분성 아미노산 수용기 길항질 화합물 | |
| UA66750C2 (en) | Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors | |
| YU104690A (sh) | Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2 | |
| RU93046497A (ru) | Фенильные гетероциклические производные, способ их получения, фармацевтическая композиция и промежуточный продукт | |
| NO944578L (no) | Eksitatoriske aminosyre reseptor antagonister | |
| HUT55369A (en) | Herbicidal compositions and process for producing sulfonylamino-carbonyl triazolinone derivatives and their intermediates used as active ingredient | |
| BG101110A (bg) | Заместени пиримидинови съединения и тяхното използване | |
| EP0394905A3 (en) | Excitatory amino acid antagonists | |
| PT927184E (pt) | Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao | |
| CA2087091A1 (en) | Excitatory amino acid antagonists | |
| IL94377A (en) | Pyridine derivatives which antagonize the effects of excitatory amino acids upon the nmda receptor complex and pharmaceutical compositions comprising them | |
| GR1001597B (el) | Νέα βιολογικώς δραστικά παράγωγα εμπουρναμενίνης, φαρμακευτικές συν?έσεις οι οποίες περιέχουν αυτά και μέ?οδος δια την παρασκευή αυτών. | |
| FI93210B (fi) | Menetelmä virusvastaisen yhdisteen valmistamiseksi | |
| DK0617616T3 (da) | Potensering af NMDA-antagonister | |
| DK0639197T3 (cg-RX-API-DMAC7.html) | ||
| AU8653891A (en) | Amino acid analogs as cck antagonists | |
| DE68902490D1 (de) | Pharmazeutische zusammensetzung. | |
| ZA916918B (en) | Amino acid analogs as CCK antagonists. | |
| DK0552712T3 (da) | 8-(1-aminocycloalkyl)1,3-dialkylxanthinderivater som antagonister for adenosinreceptorer | |
| FI890678A0 (fi) | Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi | |
| HUT67301A (en) | Nmda antagonists quinolinic derivatives, their preparation and pharmaceutical compositions comprising them | |
| FI932206A7 (fi) | Uusia heterosyklisiä yhdisteitä ekskitatoristen aminohapporeseptorien antagonisteina, menetelmä niiden valmistamiseksi ja niiden käyttö | |
| IT8023601A0 (it) | Derivati ammidici dell'acido p-isobutilfenilpropionico, procedimento per la loro preparazione e relative composizioni farmaceutici. |