ZA917355B - Antiproliferative substituted naphthalene compounds - Google Patents

Antiproliferative substituted naphthalene compounds

Info

Publication number
ZA917355B
ZA917355B ZA917355A ZA917355A ZA917355B ZA 917355 B ZA917355 B ZA 917355B ZA 917355 A ZA917355 A ZA 917355A ZA 917355 A ZA917355 A ZA 917355A ZA 917355 B ZA917355 B ZA 917355B
Authority
ZA
South Africa
Prior art keywords
substituted naphthalene
naphthalene compounds
antiproliferative
antiproliferative substituted
compounds
Prior art date
Application number
ZA917355A
Other languages
English (en)
Inventor
Michael D Varney
D Varney Michael
Gifford P Marzoni
P Marzoni Gifford
Cynthia L Palmer
L Palmer Cynthia
Judith G Pack
G Pack Judith
Original Assignee
Agouron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharma filed Critical Agouron Pharma
Publication of ZA917355B publication Critical patent/ZA917355B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C07D209/92—Naphthostyrils

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA917355A 1990-09-17 1991-09-16 Antiproliferative substituted naphthalene compounds ZA917355B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58397090A 1990-09-17 1990-09-17

Publications (1)

Publication Number Publication Date
ZA917355B true ZA917355B (en) 1992-08-26

Family

ID=24335366

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA917355A ZA917355B (en) 1990-09-17 1991-09-16 Antiproliferative substituted naphthalene compounds

Country Status (11)

Country Link
US (1) US5574039A (xx)
EP (1) EP0550566A1 (xx)
JP (1) JPH07502972A (xx)
CN (1) CN1062904A (xx)
AU (2) AU8545091A (xx)
CA (1) CA2091688A1 (xx)
FI (1) FI931156A (xx)
IL (1) IL99500A0 (xx)
MX (1) MX9101102A (xx)
WO (1) WO1992005153A1 (xx)
ZA (1) ZA917355B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9225475D0 (en) * 1992-12-05 1993-01-27 Imp Cancer Res Tech Compounds to combat angiogenesis
US5594139A (en) * 1993-01-29 1997-01-14 Agouron Pharmaceuticals, Inc. Processes for preparing antiproliferative garft-inhibiting compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
US5608082A (en) * 1994-07-28 1997-03-04 Agouron Pharmaceuticals, Inc. Compounds useful as antiproliferative agents and GARFT inhibitors
US5831100A (en) * 1995-06-07 1998-11-03 Agouron Pharmaceuticals, Inc. Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
KR100961891B1 (ko) * 2008-02-01 2010-06-09 연세대학교 산학협력단 혈관신생 억제용 약제학적 조성물
CN104877976B (zh) * 2010-09-16 2018-05-01 独立行政法人海洋研究开发机构 新的细胞外分泌型核酸酶
CN105985282B (zh) * 2015-01-28 2020-12-08 中国科学院广州生物医药与健康研究院 一种2-氧代-1,2-二氢苯并[cd]吲哚类化合物及其应用
KR102343865B1 (ko) * 2018-11-09 2021-12-28 한국화학연구원 Yap-tead 결합을 저해하는 화합물 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약제학적 조성물
CN109665987B (zh) * 2018-12-28 2022-02-18 河南大学 萘内酰亚胺-多胺缀合物及其制备方法和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3347865A (en) * 1967-10-17 Hybrocarbon-z-tertiary amino carbo- cvclic aryl benz-[c,d]-indoles
US3330834A (en) * 1967-07-11 Naphthalimide whitening agents anb method of making same
US3291808A (en) * 1961-08-14 1966-12-13 Parke Davis & Co Naphthalene diamine compounds and methods for their production
DD100731A5 (xx) * 1971-06-08 1973-10-05
BE794154A (fr) * 1972-01-19 1973-07-17 Bayer Ag Colorants cationiques, leur obtention et leurs applications
DE2328163A1 (de) * 1973-06-02 1974-12-19 Basf Ag Basische arylmercaptonaphtholactamfarbstoffe
DE2341289A1 (de) * 1973-08-16 1975-03-06 Hoechst Ag Basische farbstoffe, verfahren zu ihrer herstellung und ihre verwendung
DE2415027A1 (de) * 1974-03-28 1975-10-16 Basf Ag Farbstoffe der naphthalimidreihe
US4147865A (en) * 1976-01-30 1979-04-03 Bayer Aktiengesellschaft Benz-(C,D)-indolyl compounds
US4200752A (en) * 1978-02-16 1980-04-29 Bertelson Robert C 4-Disubstituted amino, N-substituted naphthalimide dyestuffs
DE3148104A1 (de) * 1981-12-04 1983-06-09 Bayer Ag, 5090 Leverkusen Kationische farbstoffe, verfahren zu ihrer herstellung sowie ihre verwendung zum faerben und massefaerben von textilmaterialien und anderen substraten
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
US5147568A (en) * 1991-05-07 1992-09-15 Ciba-Geigy Corporation Substituted 2,3-dihydroperimidine stabilizers

Also Published As

Publication number Publication date
IL99500A0 (en) 1992-08-18
FI931156A (fi) 1993-04-21
JPH07502972A (ja) 1995-03-30
CN1062904A (zh) 1992-07-22
CA2091688A1 (en) 1992-03-18
AU3068395A (en) 1995-11-30
FI931156A0 (fi) 1993-03-16
EP0550566A1 (en) 1993-07-14
MX9101102A (es) 1992-05-04
US5574039A (en) 1996-11-12
WO1992005153A1 (en) 1992-04-02
AU8545091A (en) 1992-04-15

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