ZA908001B - Inosine/guanosine derivatives as immunosuppressive agents - Google Patents

Inosine/guanosine derivatives as immunosuppressive agents

Info

Publication number
ZA908001B
ZA908001B ZA908001A ZA908001A ZA908001B ZA 908001 B ZA908001 B ZA 908001B ZA 908001 A ZA908001 A ZA 908001A ZA 908001 A ZA908001 A ZA 908001A ZA 908001 B ZA908001 B ZA 908001B
Authority
ZA
South Africa
Prior art keywords
inosine
immunosuppressive agents
guanosine derivatives
guanosine
derivatives
Prior art date
Application number
ZA908001A
Other languages
English (en)
Inventor
Esa Tero Jarvi
Tero Jarvi Esa
James Ray Mccarthy
Ray Mccarthy James
Terry Lynn Bowlin
Lynn Bowlin Terry
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA908001B publication Critical patent/ZA908001B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA908001A 1989-10-11 1990-10-05 Inosine/guanosine derivatives as immunosuppressive agents ZA908001B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41998889A 1989-10-11 1989-10-11

Publications (1)

Publication Number Publication Date
ZA908001B true ZA908001B (en) 1991-08-28

Family

ID=23664601

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908001A ZA908001B (en) 1989-10-11 1990-10-05 Inosine/guanosine derivatives as immunosuppressive agents

Country Status (6)

Country Link
EP (1) EP0423618A1 (xx)
JP (1) JPH03133993A (xx)
KR (1) KR910007534A (xx)
AU (1) AU635339B2 (xx)
IE (1) IE903632A1 (xx)
ZA (1) ZA908001B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU629988B2 (en) * 1989-10-11 1992-10-15 Merrell Dow Pharmaceuticals Inc. Inosine/guanosine derivatives as antineoplastic agents
ZA916350B (en) * 1990-08-16 1992-05-27 Merrell Dow Pharma 5'-vinylhalo-aristeromycin/adenosine analogs as immunosuppressants
IL152959A0 (en) * 2000-06-08 2003-06-24 Intercell Biomedizinische Forschungs & Entwicklungs Gmbh Immunostimulatory oligodeoxynucleotides
CN102212098B (zh) * 2010-04-12 2014-01-08 北京大学 新型环焦磷酸酯类化合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA869297B (en) * 1985-12-13 1987-11-25 Scripps Clinic Res Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl)derivatives
NZ225906A (en) * 1987-08-26 1990-10-26 Merrell Dow Pharma Aristeromycin/adenosine derivatives and pharmaceutical compositions
US4897177A (en) * 1988-03-23 1990-01-30 Exxon Chemical Patents Inc. Process for reforming a hydrocarbon fraction with a limited C9 + content
AU629988B2 (en) * 1989-10-11 1992-10-15 Merrell Dow Pharmaceuticals Inc. Inosine/guanosine derivatives as antineoplastic agents

Also Published As

Publication number Publication date
AU635339B2 (en) 1993-03-18
KR910007534A (ko) 1991-05-30
AU6384090A (en) 1991-04-18
EP0423618A1 (en) 1991-04-24
IE903632A1 (en) 1991-04-24
JPH03133993A (ja) 1991-06-07

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