OA09677A - Nucleoside derivatives - Google Patents

Nucleoside derivatives

Info

Publication number
OA09677A
OA09677A OA60286A OA60286A OA09677A OA 09677 A OA09677 A OA 09677A OA 60286 A OA60286 A OA 60286A OA 60286 A OA60286 A OA 60286A OA 09677 A OA09677 A OA 09677A
Authority
OA
OAPI
Prior art keywords
nucleoside derivatives
nucleoside
derivatives
Prior art date
Application number
OA60286A
Inventor
Jo Klaveness
Kjell Undheim
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27265029&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA09677(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB909007566A external-priority patent/GB9007566D0/en
Priority claimed from GB909007650A external-priority patent/GB9007650D0/en
Priority claimed from GB909007651A external-priority patent/GB9007651D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of OA09677A publication Critical patent/OA09677A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
OA60286A 1990-04-04 1992-10-02 Nucleoside derivatives OA09677A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909007566A GB9007566D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives
GB909007650A GB9007650D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives
GB909007651A GB9007651D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives

Publications (1)

Publication Number Publication Date
OA09677A true OA09677A (en) 1993-05-15

Family

ID=27265029

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60286A OA09677A (en) 1990-04-04 1992-10-02 Nucleoside derivatives

Country Status (6)

Country Link
EP (1) EP0523110A1 (en)
JP (1) JPH05505815A (en)
AU (1) AU7558491A (en)
CA (1) CA2079796A1 (en)
OA (1) OA09677A (en)
WO (1) WO1991015498A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006554A1 (en) * 1989-11-06 1991-05-16 Nycomed As Nucleoside derivatives
UA41261C2 (en) * 1992-06-22 2001-09-17 Елі Ліллі Енд Компані METHOD OF OBTAINING BETA-ANOMER-ENRICHED NUCLEOSIDES
YU43193A (en) * 1992-06-22 1997-01-08 Eli Lilly And Company 2'-DEOXY-2 ', 2'-DIFLUORO (4-SUBSTITUTED) PYRIMIDINE NUCLEOSIDS OF ANTIVIRUS AND ANTICANCEROGENIC ACTIVITY AND INTERMEDIATES
JPH0692987A (en) * 1992-09-17 1994-04-05 Tanabe Seiyaku Co Ltd Uridine derivative and its production
JPH11217396A (en) * 1998-01-30 1999-08-10 Ajinomoto Co Inc Production of nucleoside derivative
US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
US7435755B2 (en) 2000-11-28 2008-10-14 The Trustees Of Dartmouth College CDDO-compounds and combination therapies thereof
EP1465615B1 (en) 2002-01-15 2012-08-01 Trustees of Dartmouth College Tricyclic-bis-enone derivatives and methods of use thereof
US7265096B2 (en) 2002-11-04 2007-09-04 Xenoport, Inc. Gemcitabine prodrugs, pharmaceutical compositions and uses thereof
CN1693309A (en) * 2005-04-18 2005-11-09 成都正开生物科技发展有限公司 N4 (substituted oxycarbonyl) 2',2'-bifluoro-2'-deoxycytidine derivate and application thereof
WO2008064132A2 (en) 2006-11-17 2008-05-29 Trustees Of Dartmouth College Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth
JP2010510243A (en) 2006-11-17 2010-04-02 トラスティーズ オブ ダートマス カレッジ Synthesis and biological activity of tricyclic-bis-enone (TBE)
US8921340B2 (en) 2006-11-17 2014-12-30 Trustees Of Dartmouth College Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions
RS58486B1 (en) 2008-01-11 2019-04-30 Reata Pharmaceuticals Inc Synthetic triterpenoids and methods of use in the treatment of disease
CN102164941B (en) 2008-04-18 2015-05-27 里亚塔医药公司 Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring
BRPI0911422B8 (en) 2008-04-18 2021-05-25 Reata Pharmaceuticals Inc inflammatory antioxidant modulating compounds, pharmaceutical composition and their uses
CN102066397B (en) 2008-04-18 2013-09-11 里亚塔医药公司 Compounds including an anti-inflammatory pharmacore and methods of use
PL2276493T3 (en) 2008-04-18 2019-05-31 Reata Pharmaceuticals Inc Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at c-17
TW201004627A (en) 2008-04-18 2010-02-01 Reata Pharmaceuticals Inc Antioxidant inflammation modulators: novel derivatives of oleanolic acid
EA031986B1 (en) 2012-04-04 2019-03-29 Галозим, Инк. Method and combination for treating solid tumor cancer and kit comprising the combination
US8921419B2 (en) 2012-05-08 2014-12-30 Trustees Of Dartmouth College Triterpenoids and compositions containing the same
WO2016078397A1 (en) * 2014-11-17 2016-05-26 常州方圆制药有限公司 New type of cytidine derivative and application thereof
WO2016078160A1 (en) * 2014-11-17 2016-05-26 常州方圆制药有限公司 Cytidine derivative and application thereof
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
GR1009958B (en) * 2019-04-24 2021-03-18 ΕΝΟΡΑΣΙΣ ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΚΑΙ ΙΑΤΡΙΚΩΝ ΥΛΙΚΩΝ ΚΑΙ ΜΗΧΑΝΗΜΑΤΩΝ με δ.τ. "ΕΝΟΡΑΣΙΣ Α.Ε." Gemcitabine derivatives and methods of forming gemcotabine derivatives

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651045A (en) * 1968-10-21 1972-03-21 Parke Davis & Co 9-(beta-d-arabinofuranosyl)adenine esters and methods for their production
FI70903C (en) * 1980-06-23 1986-10-27 Univ Minnesota FRAMEWORK FOR THE ADMINISTRATION OF THERAPEUTIC ACTIVITIES
DE3100478A1 (en) * 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ESTERS OF PYRIMIDINE NUCLEOSIDES WITH ANTIVIRAL EFFECTIVENESS, METHOD FOR THE PRODUCTION AND MEDICINAL PRODUCTS THEREOF
US4495180A (en) * 1982-06-21 1985-01-22 Merck & Co., Inc. Prodrugs of Ara-A an antiviral agent
EP0104857A1 (en) * 1982-09-28 1984-04-04 Beecham Group Plc Deoxyuridine compounds, methods for preparing them and their use in medicine
DE3481191D1 (en) * 1983-07-20 1990-03-08 Teijin Ltd ANTINEOPLASTIC AGENT.
DK167377B1 (en) * 1985-09-17 1993-10-25 Wellcome Found 3'-AZIDOPYRIMIDINE NUCLEOSIDES OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF USED FOR TREATMENT OR PROPHYLAXY FOR A HUMAN RETROVIRUS INFECTION
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
US4780452A (en) * 1986-09-08 1988-10-25 Burroughs Wellcome Co. F-substituted-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridines and pharmaceutical compositions thereof
NZ223990A (en) * 1987-03-24 1990-08-28 Nycomed As Acylated 2',3'-dideoxynucleosides and pharmaceutical compositions
IL89258A0 (en) * 1988-02-16 1989-09-10 Lilly Co Eli 2',3'-dideoxy-2',2'-difluoro-nucleosides
JPH02152976A (en) * 1988-05-06 1990-06-12 Bristol Myers Co Prodrug of 2',3'-didehydro-2',3'-dideoxynucleoside
US4900828A (en) * 1988-05-12 1990-02-13 Hoffmann-Laroche Inc. Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine
EP0346108A3 (en) * 1988-06-09 1991-04-24 The Wellcome Foundation Limited Anti-infective nucleosides
EP0355031A3 (en) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituted pyrimidine nucleosides, process for their preparation and pharmaceutical compounds containing them
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8823319D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8920534D0 (en) * 1989-09-11 1989-10-25 Wellcome Found Antiviral compounds

Also Published As

Publication number Publication date
AU7558491A (en) 1991-10-30
WO1991015498A2 (en) 1991-10-17
JPH05505815A (en) 1993-08-26
CA2079796A1 (en) 1991-10-05
WO1991015498A3 (en) 1992-06-11
EP0523110A1 (en) 1993-01-20

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