OA09677A - Nucleoside derivatives - Google Patents
Nucleoside derivativesInfo
- Publication number
- OA09677A OA09677A OA60286A OA60286A OA09677A OA 09677 A OA09677 A OA 09677A OA 60286 A OA60286 A OA 60286A OA 60286 A OA60286 A OA 60286A OA 09677 A OA09677 A OA 09677A
- Authority
- OA
- OAPI
- Prior art keywords
- nucleoside derivatives
- nucleoside
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909007566A GB9007566D0 (en) | 1990-04-04 | 1990-04-04 | Nucleoside derivatives |
GB909007650A GB9007650D0 (en) | 1990-04-04 | 1990-04-04 | Nucleoside derivatives |
GB909007651A GB9007651D0 (en) | 1990-04-04 | 1990-04-04 | Nucleoside derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
OA09677A true OA09677A (en) | 1993-05-15 |
Family
ID=27265029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA60286A OA09677A (en) | 1990-04-04 | 1992-10-02 | Nucleoside derivatives |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0523110A1 (en) |
JP (1) | JPH05505815A (en) |
AU (1) | AU7558491A (en) |
CA (1) | CA2079796A1 (en) |
OA (1) | OA09677A (en) |
WO (1) | WO1991015498A2 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991006554A1 (en) * | 1989-11-06 | 1991-05-16 | Nycomed As | Nucleoside derivatives |
UA41261C2 (en) * | 1992-06-22 | 2001-09-17 | Елі Ліллі Енд Компані | METHOD OF OBTAINING BETA-ANOMER-ENRICHED NUCLEOSIDES |
YU43193A (en) * | 1992-06-22 | 1997-01-08 | Eli Lilly And Company | 2'-DEOXY-2 ', 2'-DIFLUORO (4-SUBSTITUTED) PYRIMIDINE NUCLEOSIDS OF ANTIVIRUS AND ANTICANCEROGENIC ACTIVITY AND INTERMEDIATES |
JPH0692987A (en) * | 1992-09-17 | 1994-04-05 | Tanabe Seiyaku Co Ltd | Uridine derivative and its production |
JPH11217396A (en) * | 1998-01-30 | 1999-08-10 | Ajinomoto Co Inc | Production of nucleoside derivative |
US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
US7435755B2 (en) | 2000-11-28 | 2008-10-14 | The Trustees Of Dartmouth College | CDDO-compounds and combination therapies thereof |
EP1465615B1 (en) | 2002-01-15 | 2012-08-01 | Trustees of Dartmouth College | Tricyclic-bis-enone derivatives and methods of use thereof |
US7265096B2 (en) | 2002-11-04 | 2007-09-04 | Xenoport, Inc. | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof |
CN1693309A (en) * | 2005-04-18 | 2005-11-09 | 成都正开生物科技发展有限公司 | N4 (substituted oxycarbonyl) 2',2'-bifluoro-2'-deoxycytidine derivate and application thereof |
WO2008064132A2 (en) | 2006-11-17 | 2008-05-29 | Trustees Of Dartmouth College | Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth |
JP2010510243A (en) | 2006-11-17 | 2010-04-02 | トラスティーズ オブ ダートマス カレッジ | Synthesis and biological activity of tricyclic-bis-enone (TBE) |
US8921340B2 (en) | 2006-11-17 | 2014-12-30 | Trustees Of Dartmouth College | Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions |
RS58486B1 (en) | 2008-01-11 | 2019-04-30 | Reata Pharmaceuticals Inc | Synthetic triterpenoids and methods of use in the treatment of disease |
CN102164941B (en) | 2008-04-18 | 2015-05-27 | 里亚塔医药公司 | Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring |
BRPI0911422B8 (en) | 2008-04-18 | 2021-05-25 | Reata Pharmaceuticals Inc | inflammatory antioxidant modulating compounds, pharmaceutical composition and their uses |
CN102066397B (en) | 2008-04-18 | 2013-09-11 | 里亚塔医药公司 | Compounds including an anti-inflammatory pharmacore and methods of use |
PL2276493T3 (en) | 2008-04-18 | 2019-05-31 | Reata Pharmaceuticals Inc | Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at c-17 |
TW201004627A (en) | 2008-04-18 | 2010-02-01 | Reata Pharmaceuticals Inc | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
EA031986B1 (en) | 2012-04-04 | 2019-03-29 | Галозим, Инк. | Method and combination for treating solid tumor cancer and kit comprising the combination |
US8921419B2 (en) | 2012-05-08 | 2014-12-30 | Trustees Of Dartmouth College | Triterpenoids and compositions containing the same |
WO2016078397A1 (en) * | 2014-11-17 | 2016-05-26 | 常州方圆制药有限公司 | New type of cytidine derivative and application thereof |
WO2016078160A1 (en) * | 2014-11-17 | 2016-05-26 | 常州方圆制药有限公司 | Cytidine derivative and application thereof |
WO2019222435A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
GR1009958B (en) * | 2019-04-24 | 2021-03-18 | ΕΝΟΡΑΣΙΣ ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΚΑΙ ΙΑΤΡΙΚΩΝ ΥΛΙΚΩΝ ΚΑΙ ΜΗΧΑΝΗΜΑΤΩΝ με δ.τ. "ΕΝΟΡΑΣΙΣ Α.Ε." | Gemcitabine derivatives and methods of forming gemcotabine derivatives |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3651045A (en) * | 1968-10-21 | 1972-03-21 | Parke Davis & Co | 9-(beta-d-arabinofuranosyl)adenine esters and methods for their production |
FI70903C (en) * | 1980-06-23 | 1986-10-27 | Univ Minnesota | FRAMEWORK FOR THE ADMINISTRATION OF THERAPEUTIC ACTIVITIES |
DE3100478A1 (en) * | 1981-01-09 | 1982-08-12 | Dr. Thilo & Co GmbH, 8021 Sauerlach | 5'ESTERS OF PYRIMIDINE NUCLEOSIDES WITH ANTIVIRAL EFFECTIVENESS, METHOD FOR THE PRODUCTION AND MEDICINAL PRODUCTS THEREOF |
US4495180A (en) * | 1982-06-21 | 1985-01-22 | Merck & Co., Inc. | Prodrugs of Ara-A an antiviral agent |
EP0104857A1 (en) * | 1982-09-28 | 1984-04-04 | Beecham Group Plc | Deoxyuridine compounds, methods for preparing them and their use in medicine |
DE3481191D1 (en) * | 1983-07-20 | 1990-03-08 | Teijin Ltd | ANTINEOPLASTIC AGENT. |
DK167377B1 (en) * | 1985-09-17 | 1993-10-25 | Wellcome Found | 3'-AZIDOPYRIMIDINE NUCLEOSIDES OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF USED FOR TREATMENT OR PROPHYLAXY FOR A HUMAN RETROVIRUS INFECTION |
US4751221A (en) * | 1985-10-18 | 1988-06-14 | Sloan-Kettering Institute For Cancer Research | 2-fluoro-arabinofuranosyl purine nucleosides |
US4780452A (en) * | 1986-09-08 | 1988-10-25 | Burroughs Wellcome Co. | F-substituted-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridines and pharmaceutical compositions thereof |
NZ223990A (en) * | 1987-03-24 | 1990-08-28 | Nycomed As | Acylated 2',3'-dideoxynucleosides and pharmaceutical compositions |
IL89258A0 (en) * | 1988-02-16 | 1989-09-10 | Lilly Co Eli | 2',3'-dideoxy-2',2'-difluoro-nucleosides |
JPH02152976A (en) * | 1988-05-06 | 1990-06-12 | Bristol Myers Co | Prodrug of 2',3'-didehydro-2',3'-dideoxynucleoside |
US4900828A (en) * | 1988-05-12 | 1990-02-13 | Hoffmann-Laroche Inc. | Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine |
EP0346108A3 (en) * | 1988-06-09 | 1991-04-24 | The Wellcome Foundation Limited | Anti-infective nucleosides |
EP0355031A3 (en) * | 1988-08-17 | 1990-12-27 | MATTHES, Eckart, Dr. | Substituted pyrimidine nucleosides, process for their preparation and pharmaceutical compounds containing them |
GB8823320D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
GB8823319D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
GB8920534D0 (en) * | 1989-09-11 | 1989-10-25 | Wellcome Found | Antiviral compounds |
-
1991
- 1991-04-04 AU AU75584/91A patent/AU7558491A/en not_active Abandoned
- 1991-04-04 WO PCT/EP1991/000639 patent/WO1991015498A2/en not_active Application Discontinuation
- 1991-04-04 JP JP91506841A patent/JPH05505815A/en active Pending
- 1991-04-04 CA CA002079796A patent/CA2079796A1/en not_active Abandoned
- 1991-04-04 EP EP91906957A patent/EP0523110A1/en not_active Withdrawn
-
1992
- 1992-10-02 OA OA60286A patent/OA09677A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU7558491A (en) | 1991-10-30 |
WO1991015498A2 (en) | 1991-10-17 |
JPH05505815A (en) | 1993-08-26 |
CA2079796A1 (en) | 1991-10-05 |
WO1991015498A3 (en) | 1992-06-11 |
EP0523110A1 (en) | 1993-01-20 |
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