ZA906511B - Use of amide complex compounds - Google Patents

Use of amide complex compounds

Info

Publication number
ZA906511B
ZA906511B ZA906511A ZA906511A ZA906511B ZA 906511 B ZA906511 B ZA 906511B ZA 906511 A ZA906511 A ZA 906511A ZA 906511 A ZA906511 A ZA 906511A ZA 906511 B ZA906511 B ZA 906511B
Authority
ZA
South Africa
Prior art keywords
complex compounds
amide complex
amide
compounds
complex
Prior art date
Application number
ZA906511A
Inventor
Bernd Raduechel
Raduechel Bernd
Heribert Schmitt-Willich
Schmitt-Willich Heribert
Heinz Gries
Gries Heinz
Gabriele Schuhmann-Giampieri
Schuhmann-Giampieri Gabriele
Hubert Vogler
Vogler Hubert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA906511B publication Critical patent/ZA906511B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA906511A 1989-08-16 1990-08-16 Use of amide complex compounds ZA906511B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927444A DE3927444A1 (en) 1989-08-16 1989-08-16 USE OF AMID COMPLEX COMPOUNDS

Publications (1)

Publication Number Publication Date
ZA906511B true ZA906511B (en) 1991-09-25

Family

ID=6387458

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906511A ZA906511B (en) 1989-08-16 1990-08-16 Use of amide complex compounds

Country Status (10)

Country Link
EP (1) EP0413405A3 (en)
JP (1) JPH03173856A (en)
AU (1) AU6107390A (en)
DE (1) DE3927444A1 (en)
FI (1) FI904060A0 (en)
IE (1) IE902964A1 (en)
IL (1) IL95394A0 (en)
NO (1) NO903597L (en)
PT (1) PT95008A (en)
ZA (1) ZA906511B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077037A (en) * 1990-08-03 1991-12-31 Mallinckrodt Medical, Inc. Novel compositions for magnetic resonance imaging
GB9024208D0 (en) * 1990-11-07 1990-12-19 Salutar Inc Compounds
GB9027922D0 (en) * 1990-12-21 1991-02-13 Nycomed As Compounds
US5463030A (en) * 1991-05-03 1995-10-31 Research Foundation Of The State Of New York Metal chelating agents for medical application
WO1992021017A1 (en) * 1991-05-23 1992-11-26 Unger Evan C Liposoluble compounds for magnetic resonance imaging
US6875864B2 (en) 1991-08-01 2005-04-05 Bracco International B.V. Aminocarboxylate ligands having substituted aromatic amide moieties
WO1993003351A1 (en) * 1991-08-09 1993-02-18 The Regents Of The University Of California Amino acid, ester and/or catechol contrast agents for mri
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
GB9208908D0 (en) * 1992-04-24 1992-06-10 Nycomed As Contrast agents
CA2116867C (en) * 1992-07-03 2004-04-27 The Green Cross Corporation Novel chelating agent, complex compound of said chelating agent and metallic atom, and diagnostic agent comprising same
DE4317588C2 (en) * 1993-05-24 1998-04-16 Schering Ag Macrocyclic metal complexes containing fluorine, process for their preparation and their use
DE4318369C1 (en) * 1993-05-28 1995-02-09 Schering Ag Use of macrocyclic metal complexes as temperature probes
US5733528A (en) * 1993-12-03 1998-03-31 Dibra S.P.A. Paramagnetic chelates for nuclear magnetic resonance diagnosis
EP0702677A1 (en) * 1994-04-08 1996-03-27 BRACCO International B.V. Aromatic amide compounds and metal chelates thereof
DE19507819A1 (en) * 1995-02-21 1996-08-22 Schering Ag New di:ethylene-tri:amine penta:acetic acid amide complexes
IL117200A0 (en) * 1995-02-21 1996-06-18 Schering Ag Diethylenetriamine-pentaacetic acid monoamide derivatives pharmaceutical compostions containing the same and processes for the preparation thereof
DE19507820A1 (en) * 1995-02-21 1996-08-22 Schering Ag Novel substituted DTPA derivatives, their metal complexes, pharmaceutical compositions containing these complexes, their use in diagnostics, and methods for producing the complexes and compositions
DE19507822B4 (en) * 1995-02-21 2006-07-20 Schering Ag Substituted DTPA monoamides of the central carboxylic acid and its metal complexes, pharmaceutical compositions containing these complexes, their use in diagnostics and therapy, and methods for the preparation of the complexes and agents
DE19646762B4 (en) * 1996-11-04 2004-05-13 Schering Ag Use of metal compounds for the production of agents for radiotherapy of tumors
JP5406459B2 (en) * 2008-02-20 2014-02-05 光司 山下 Gadolinium compound and contrast medium for MRI

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474533A (en) * 1966-12-14 1969-06-30 Geigy Ag J R Process for the preparation of bis-carboxylic acid anhydrides
DE3129906C3 (en) * 1981-07-24 1996-12-19 Schering Ag Paramagnetic complex salts, their preparation and agents for use in NMR diagnostics
NL194579C (en) * 1983-01-21 2002-08-05 Schering Ag Diagnostic.
US4687659A (en) * 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
IL83966A (en) * 1986-09-26 1992-03-29 Schering Ag Amides of aminopolycarboxylic acids and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IE902964A1 (en) 1991-02-27
EP0413405A3 (en) 1991-10-16
NO903597D0 (en) 1990-08-15
PT95008A (en) 1991-04-18
FI904060A0 (en) 1990-08-16
JPH03173856A (en) 1991-07-29
DE3927444A1 (en) 1991-02-28
IL95394A0 (en) 1991-06-30
AU6107390A (en) 1991-02-21
EP0413405A2 (en) 1991-02-20
NO903597L (en) 1991-02-18

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