ZA906060B - Antibiotic compounds - Google Patents
Antibiotic compoundsInfo
- Publication number
- ZA906060B ZA906060B ZA906060A ZA906060A ZA906060B ZA 906060 B ZA906060 B ZA 906060B ZA 906060 A ZA906060 A ZA 906060A ZA 906060 A ZA906060 A ZA 906060A ZA 906060 B ZA906060 B ZA 906060B
- Authority
- ZA
- South Africa
- Prior art keywords
- antibiotic compounds
- formula
- ring
- coch2
- cleavable
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP89402289 | 1989-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA906060B true ZA906060B (en) | 1991-05-29 |
Family
ID=8202985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA906060A ZA906060B (en) | 1989-08-11 | 1990-08-01 | Antibiotic compounds |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5219848A (fr) |
| EP (1) | EP0412763B1 (fr) |
| JP (1) | JPH03128384A (fr) |
| AT (1) | ATE140230T1 (fr) |
| AU (1) | AU6014390A (fr) |
| CA (1) | CA2022664A1 (fr) |
| DE (1) | DE69027718T2 (fr) |
| FI (1) | FI903963A0 (fr) |
| NO (1) | NO903360L (fr) |
| PT (1) | PT94959A (fr) |
| ZA (1) | ZA906060B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5215982A (en) * | 1989-11-10 | 1993-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| CA2135781A1 (fr) * | 1993-04-13 | 1994-10-27 | Jorg Frei | Ornithine decarboxylase inhibant les derives aminoxyamino-alcane ramifies |
| CN102040615B (zh) * | 2009-10-12 | 2012-12-26 | 山东轩竹医药科技有限公司 | 含有二氢吡咯并环烷基的头孢抗生素 |
| JP6151257B2 (ja) | 2011-09-09 | 2017-06-21 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 肺内感染症の治療方法 |
| US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| US20140274993A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane-tazobactam pharmaceutical compositions |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| EP3100732A1 (fr) | 2013-03-15 | 2016-12-07 | Merck Sharp & Dohme Corp. | Compositions antibiotiques de ceftolozane |
| US10376496B2 (en) | 2013-09-09 | 2019-08-13 | Merck, Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52119885A (en) * | 1976-04-01 | 1977-10-07 | Sony Corp | Gas laser tube |
| US4278733A (en) * | 1979-07-23 | 1981-07-14 | Spaulding Fibre Company, Inc. | Epoxy modified aniline-phenolic laminate |
| US4855420A (en) * | 1983-06-03 | 1989-08-08 | Ici Pharma | Cephalosporin derivatives |
| DE3581891D1 (de) * | 1984-11-12 | 1991-04-04 | Banyu Pharma Co Ltd | Cephalosporinderivate. |
| US4959469A (en) * | 1984-12-27 | 1990-09-25 | Banyu Pharmaceutical Company, Ltd. | Crystalline cephalosporin compounds |
| CA1267647A (fr) * | 1984-12-27 | 1990-04-10 | Ryosuke Ushijima | Derives de cephalosporine |
| US4728733A (en) * | 1985-11-25 | 1988-03-01 | American Home Products Corporation | C-3' thiadiazinyl cephalosporin analogs |
| US4728734A (en) * | 1985-11-25 | 1988-03-01 | American Home Products Corporation | C-3'thioiminosulfonyl cephalosporin analogs |
| US4728732A (en) * | 1985-11-25 | 1988-03-01 | American Home Products Corporation | C-3'acylsulfonamido cephalosporin analogs |
| GB8611823D0 (en) * | 1986-05-15 | 1986-06-25 | Ici Plc | Process |
| ZA877987B (en) * | 1986-11-12 | 1988-08-31 | Ici Pharma | Antibiotic compounds |
| EP0269298B1 (fr) * | 1986-11-21 | 1994-10-19 | Ici Pharma | Céphalosporines, leur procédé de préparation et compositions pharmaceutiques |
-
1990
- 1990-07-30 NO NO90903360A patent/NO903360L/no unknown
- 1990-08-01 ZA ZA906060A patent/ZA906060B/xx unknown
- 1990-08-03 CA CA002022664A patent/CA2022664A1/fr not_active Abandoned
- 1990-08-03 AU AU60143/90A patent/AU6014390A/en not_active Abandoned
- 1990-08-07 EP EP90308657A patent/EP0412763B1/fr not_active Expired - Lifetime
- 1990-08-07 AT AT90308657T patent/ATE140230T1/de not_active IP Right Cessation
- 1990-08-07 DE DE69027718T patent/DE69027718T2/de not_active Expired - Fee Related
- 1990-08-10 FI FI903963A patent/FI903963A0/fi not_active Application Discontinuation
- 1990-08-10 PT PT94959A patent/PT94959A/pt not_active Application Discontinuation
- 1990-08-10 US US07/565,240 patent/US5219848A/en not_active Expired - Fee Related
- 1990-08-13 JP JP2211750A patent/JPH03128384A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI903963A0 (fi) | 1990-08-10 |
| US5219848A (en) | 1993-06-15 |
| EP0412763A3 (en) | 1992-03-04 |
| DE69027718T2 (de) | 1996-12-05 |
| PT94959A (pt) | 1991-05-22 |
| CA2022664A1 (fr) | 1991-02-12 |
| EP0412763A2 (fr) | 1991-02-13 |
| ATE140230T1 (de) | 1996-07-15 |
| EP0412763B1 (fr) | 1996-07-10 |
| DE69027718D1 (de) | 1996-08-14 |
| NO903360D0 (no) | 1990-07-30 |
| JPH03128384A (ja) | 1991-05-31 |
| AU6014390A (en) | 1991-02-14 |
| NO903360L (no) | 1991-02-12 |
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