ZA904783B - 3,5,6-substituted derivatives of 1.2-o-isopropylidene-alpha-glucofuranose and intermediates for preparing these derivatives - Google Patents

3,5,6-substituted derivatives of 1.2-o-isopropylidene-alpha-glucofuranose and intermediates for preparing these derivatives

Info

Publication number
ZA904783B
ZA904783B ZA904783A ZA904783A ZA904783B ZA 904783 B ZA904783 B ZA 904783B ZA 904783 A ZA904783 A ZA 904783A ZA 904783 A ZA904783 A ZA 904783A ZA 904783 B ZA904783 B ZA 904783B
Authority
ZA
South Africa
Prior art keywords
derivatives
glucofuranose
isopropylidene
intermediates
alpha
Prior art date
Application number
ZA904783A
Other languages
English (en)
Inventor
Bruce Rosen
Rosen Bruce
Sudershan K Arora
K Arora Sudershan
Albert V Thomas
V Thomas Albert
Original Assignee
Greenwich Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenwich Pharma filed Critical Greenwich Pharma
Publication of ZA904783B publication Critical patent/ZA904783B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA904783A 1989-06-22 1990-06-20 3,5,6-substituted derivatives of 1.2-o-isopropylidene-alpha-glucofuranose and intermediates for preparing these derivatives ZA904783B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/369,932 US5010058A (en) 1989-06-22 1989-06-22 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives

Publications (1)

Publication Number Publication Date
ZA904783B true ZA904783B (en) 1991-03-27

Family

ID=23457536

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA904783A ZA904783B (en) 1989-06-22 1990-06-20 3,5,6-substituted derivatives of 1.2-o-isopropylidene-alpha-glucofuranose and intermediates for preparing these derivatives

Country Status (10)

Country Link
US (1) US5010058A (fr)
EP (1) EP0404136A3 (fr)
JP (1) JPH03163091A (fr)
KR (1) KR910000772A (fr)
AU (1) AU5769190A (fr)
CA (1) CA2019705A1 (fr)
IE (1) IE902221A1 (fr)
IL (1) IL94821A0 (fr)
NO (1) NO902750L (fr)
ZA (1) ZA904783B (fr)

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US5298494A (en) * 1989-01-09 1994-03-29 Greenwich Pharmaceuticals Incorporated Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
EP0548226A1 (fr) * 1990-09-12 1993-06-30 Greenwich Pharmaceuticals Incorporated Monosaccharides presentant une activite anti-proliferative et anti-inflammatoire, compositions et leurs utilisations
IL100833A0 (en) * 1991-02-20 1992-09-06 Greenwich Pharma Method for synthesis of ethereally substituted blocked monosaccharides
US5360792A (en) * 1991-12-20 1994-11-01 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
FR2694753B1 (fr) * 1992-07-09 1994-12-23 Picardie Jules Verne Universit Procédés de synthèse spécifique de nouveaux aminothioéthers par substitution des sites hydroxylés sur des molécules mono ou polyhydroxylées, produits obtenus par ces procédés et leurs applications.
US5360794A (en) * 1992-08-03 1994-11-01 Medicarb Inc. Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity
US5367062A (en) * 1992-08-21 1994-11-22 Medicarb Inc. Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity
US5432163A (en) * 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
TW342393B (en) * 1993-06-11 1998-10-11 Boston Life Science Co Ltd Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose
US5637570A (en) * 1995-05-09 1997-06-10 Chemora Pharmochem Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity
US6329344B1 (en) 1998-10-22 2001-12-11 Ranbaxy Laboratories Limited Derivatives of monosaccharides as cell adhesion inhibitors
IN190975B (fr) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd
US7504228B2 (en) * 2001-06-05 2009-03-17 Qlt Inc. Integrin linked kinase modulation of monocyte activation
WO2005092907A2 (fr) * 2004-03-26 2005-10-06 Ranbaxy Laboratories Limited Derives de monosaccharide
US20090221515A1 (en) * 2004-09-02 2009-09-03 Viswajanani Jitendra Sattigeri Monosaccharide derivatives
WO2007063356A2 (fr) * 2004-12-22 2007-06-07 Ranbaxy Laboratories Limited Derives de monosaccharides
EP1874788A1 (fr) * 2005-04-19 2008-01-09 Ranbaxy Laboratories Limited Derives de monosaccharides utiles comme agents anti-inflammatoires et/ou anticancereux
US20080114031A1 (en) * 2006-03-29 2008-05-15 Sattigeri Viswajanani J Monosaccharide derivatives
US7790689B2 (en) * 2006-05-30 2010-09-07 Ranbaxy Laboratories Limited Monosaccharide derivatives
EP1953170A1 (fr) * 2006-10-03 2008-08-06 Ranbaxy Laboratories Limited Dérivés de monosaccharide en tant qu'agents anti-inflammatoires
CN104387428A (zh) * 2014-12-09 2015-03-04 济南卡博唐生物科技有限公司 一种制备3,5,6-三-氧-苄基-1,2-异丙叉基-d-葡萄糖的方法
CN104530148A (zh) * 2014-12-09 2015-04-22 济南卡博唐生物科技有限公司 一种制备3,5,6-三-氧-苄基-1,2-异丙叉基-d-葡萄糖的改进方法
CN104478955A (zh) * 2014-12-09 2015-04-01 济南卡博唐生物科技有限公司 一种3,5,6-三-氧-苄基-1,2-异丙叉基-d-葡萄糖的制备方法

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US2461478A (en) * 1946-12-18 1949-02-08 Gen Aniline & Film Corp Gelatin subbing compositions having antistatic properties
US2875194A (en) * 1955-10-05 1959-02-24 American Cyanamid Co Derivatives of 5-amino-d-ribofuranose
US2960452A (en) * 1958-07-14 1960-11-15 Miles Lab Preparation of diacetone 2-keto-gulonic acid
US3586664A (en) * 1969-03-19 1971-06-22 Eisai Co Ltd Xylose derivatives and preparation thereof
US3832355A (en) * 1970-05-13 1974-08-27 Hoffmann La Roche Catalytic oxidation process
US4032650A (en) * 1972-09-15 1977-06-28 A.E.C. Societe De Chimie Organique Et Biologique Method of treating fatigue by administering a gulonic acid salt
USRE32268E (en) * 1973-03-01 1986-10-21 Strategic Medical Research Corp. Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US4016261A (en) * 1973-03-01 1977-04-05 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US3939145A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereally monosubstituted monosaccharides
US3939146A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereal monosubstitutions of monosaccharide derivatives
USRE30379E (en) * 1973-03-01 1980-08-19 Strategic Medical Research Corp. Ethereal monosubstitutions of monosaccharide derivatives
US3965262A (en) * 1973-03-01 1976-06-22 Strategic Medical Research Corporation Method of enhancing learning and/or memory in warm blooded animals
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Also Published As

Publication number Publication date
NO902750D0 (no) 1990-06-20
NO902750L (no) 1990-12-27
CA2019705A1 (fr) 1990-12-22
AU5769190A (en) 1991-01-03
US5010058A (en) 1991-04-23
IE902221L (en) 1990-12-22
IE902221A1 (en) 1991-01-16
KR910000772A (ko) 1991-01-30
JPH03163091A (ja) 1991-07-15
EP0404136A2 (fr) 1990-12-27
EP0404136A3 (fr) 1992-07-22
IL94821A0 (en) 1991-04-15

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