ZA904689B - Formation of triple helixes of double-stranded dna using nucleoside oligomers - Google Patents

Formation of triple helixes of double-stranded dna using nucleoside oligomers

Info

Publication number
ZA904689B
ZA904689B ZA904689A ZA904689A ZA904689B ZA 904689 B ZA904689 B ZA 904689B ZA 904689 A ZA904689 A ZA 904689A ZA 904689 A ZA904689 A ZA 904689A ZA 904689 B ZA904689 B ZA 904689B
Authority
ZA
South Africa
Prior art keywords
double
formation
stranded dna
triple helixes
nucleoside
Prior art date
Application number
ZA904689A
Other languages
English (en)
Inventor
Ts O Paul
Paul S Miller
S Miller Paul
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of ZA904689B publication Critical patent/ZA904689B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA904689A 1989-06-19 1990-06-18 Formation of triple helixes of double-stranded dna using nucleoside oligomers ZA904689B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36802789A 1989-06-19 1989-06-19

Publications (1)

Publication Number Publication Date
ZA904689B true ZA904689B (en) 1991-03-27

Family

ID=23449587

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA904689A ZA904689B (en) 1989-06-19 1990-06-18 Formation of triple helixes of double-stranded dna using nucleoside oligomers

Country Status (9)

Country Link
EP (1) EP0478708A4 (enrdf_load_stackoverflow)
JP (1) JPH04506152A (enrdf_load_stackoverflow)
AU (2) AU651067B2 (enrdf_load_stackoverflow)
CA (1) CA2019156A1 (enrdf_load_stackoverflow)
IL (1) IL94752A (enrdf_load_stackoverflow)
NZ (1) NZ234082A (enrdf_load_stackoverflow)
TW (1) TW221829B (enrdf_load_stackoverflow)
WO (1) WO1990015884A1 (enrdf_load_stackoverflow)
ZA (1) ZA904689B (enrdf_load_stackoverflow)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
USRE38416E1 (en) 1988-09-28 2004-02-03 Epoch Biosciences, Inc. Cross-linking oligonucleotides
US5824796A (en) * 1988-09-28 1998-10-20 Epoch Pharmaceuticals, Inc. Cross-linking oligonucleotides
CA2083719A1 (en) * 1990-05-25 1991-11-26 Mark D. Matteucci "sequence-specific non-photoactivated crosslinking agents which bind to the major groove of duplex dna
EP0566670A4 (en) * 1990-12-17 1993-12-08 Idexx Laboratories, Inc. Nucleic acid sequence detection by triple helix formation
US6136601A (en) * 1991-08-21 2000-10-24 Epoch Pharmaceuticals, Inc. Targeted mutagenesis in living cells using modified oligonucleotides
AU668886B2 (en) * 1991-08-30 1996-05-23 Johns Hopkins University, The Formation of triple helix complexes of double stranded DNA using nucleoside oligomers which comprise purine base analogs
IL103311A0 (en) * 1991-10-07 1993-03-15 Univ Johns Hopkins Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers
DE69232816T2 (de) * 1991-11-26 2003-06-18 Isis Pharmaceuticals, Inc. Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen
US6235887B1 (en) 1991-11-26 2001-05-22 Isis Pharmaceuticals, Inc. Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines
TW393513B (en) * 1991-11-26 2000-06-11 Isis Pharmaceuticals Inc Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
US5616461A (en) * 1992-05-14 1997-04-01 Dana-Farber Cancer Institute Assay for antiviral activity using complex of herpesvirus origin of replication and cellular protein
AU6296294A (en) 1993-01-26 1994-08-15 Microprobe Corporation Bifunctional crosslinking oligonucleotides adapted for linking to a desired gene sequence of invading organism or cell

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511713A (en) * 1980-11-12 1985-04-16 The Johns Hopkins University Process for selectively controlling unwanted expression or function of foreign nucleic acids in animal or mammalian cells
US4469863A (en) * 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US4757055A (en) * 1980-11-12 1988-07-12 The Johns Hopkins University Method for selectively controlling unwanted expression or function of foreign nucleic acids in animal or mammalian cells

Also Published As

Publication number Publication date
TW221829B (enrdf_load_stackoverflow) 1994-03-21
EP0478708A1 (en) 1992-04-08
NZ234082A (en) 1997-06-24
IL94752A (en) 1995-12-31
AU679111B2 (en) 1997-06-19
JPH04506152A (ja) 1992-10-29
EP0478708A4 (en) 1993-06-09
CA2019156A1 (en) 1990-12-19
WO1990015884A1 (en) 1990-12-27
AU7584594A (en) 1994-12-15
AU651067B2 (en) 1994-07-14
AU5846890A (en) 1991-01-08
IL94752A0 (en) 1991-04-15

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