ZA903139B - Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them - Google Patents

Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them

Info

Publication number
ZA903139B
ZA903139B ZA903139A ZA903139A ZA903139B ZA 903139 B ZA903139 B ZA 903139B ZA 903139 A ZA903139 A ZA 903139A ZA 903139 A ZA903139 A ZA 903139A ZA 903139 B ZA903139 B ZA 903139B
Authority
ZA
South Africa
Prior art keywords
phenylmethyl
indole
medicaments
intermediates
derivatives
Prior art date
Application number
ZA903139A
Other languages
English (en)
Inventor
Francois Clemence
Clemence Francois
Jacques Guillaume
Guillaume Jacques
Gilles Hamon
Hamon Gilles
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA903139B publication Critical patent/ZA903139B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA903139A 1989-04-28 1990-04-25 Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them ZA903139B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8905650A FR2646349B1 (fr) 1989-04-28 1989-04-28 Derives du 4-phenylmethyl lh-indole, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Publications (1)

Publication Number Publication Date
ZA903139B true ZA903139B (en) 1991-06-26

Family

ID=9381227

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903139A ZA903139B (en) 1989-04-28 1990-04-25 Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them

Country Status (16)

Country Link
US (1) US5086070A (ru)
EP (1) EP0395528B1 (ru)
JP (1) JPH0368554A (ru)
AT (1) ATE124685T1 (ru)
AU (1) AU628968B2 (ru)
CA (1) CA2015669A1 (ru)
DE (1) DE69020632T2 (ru)
DK (1) DK0395528T3 (ru)
ES (1) ES2074144T3 (ru)
FR (1) FR2646349B1 (ru)
HU (1) HUT54642A (ru)
MX (1) MX20482A (ru)
NZ (1) NZ233478A (ru)
PT (1) PT93915B (ru)
RU (1) RU2067576C1 (ru)
ZA (1) ZA903139B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908367A (en) * 1985-07-11 1990-03-13 Roussel Uclaf N-(1H-indole-4-yl)-benzamides
CH687764A5 (de) * 1992-07-02 1997-02-14 Lonza Ag Gampel Wallis Geschof Verfahren zur Herstellung von 7-Acylindolen.
CN1094487C (zh) * 1994-04-01 2002-11-20 盐野义制药株式会社 肟衍生物和含有其作为活性成分的杀菌剂
US6268312B1 (en) 1994-04-01 2001-07-31 Shionogi & Co., Ltd. Oxime derivative and bactericide containing the same as active ingredient
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
BRPI0916774A2 (pt) * 2008-07-15 2018-02-20 Hoffmann La Roche derivados de indolila e indazolila substituídos e usos dos mesmos
WO2017205296A1 (en) * 2016-05-23 2017-11-30 The Rockefeller University Aminoacylindazole immunomodulators for treatment of autoimmune diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584070B1 (fr) * 1985-06-27 1987-08-28 Roussel Uclaf Nouveaux derives de l'hydroxy alkoxy 4-phenyl propyl indole, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant.
FR2584713B1 (fr) * 1985-07-11 1988-09-09 Roussel Uclaf Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Also Published As

Publication number Publication date
HUT54642A (en) 1991-03-28
MX20482A (es) 1993-11-01
CA2015669A1 (fr) 1990-10-28
JPH0368554A (ja) 1991-03-25
DK0395528T3 (da) 1995-10-30
HU902612D0 (en) 1990-09-28
ES2074144T3 (es) 1995-09-01
PT93915B (pt) 1996-10-31
EP0395528B1 (fr) 1995-07-05
RU2067576C1 (ru) 1996-10-10
NZ233478A (en) 1992-08-26
ATE124685T1 (de) 1995-07-15
EP0395528A2 (fr) 1990-10-31
DE69020632T2 (de) 1996-01-11
US5086070A (en) 1992-02-04
PT93915A (pt) 1990-11-20
FR2646349A1 (fr) 1990-11-02
EP0395528A3 (fr) 1991-11-21
AU628968B2 (en) 1992-09-24
DE69020632D1 (de) 1995-08-10
FR2646349B1 (fr) 1994-04-01
AU5393190A (en) 1990-11-01

Similar Documents

Publication Publication Date Title
HUT54357A (en) Process for producing benzilidene-(azolylmethyl)-cycloalkane and -cycloalkene derivatives, fungicidal compositions comprising such compounds as active ingredient and intermediates usable for the production of the active ingredients
US4476308B1 (ru)
PT87275A (pt) Process for the preparation of a repugnant composition of insects and acarids containing a substituted by product of alpha omega-aminoalcohols and of certains alpha omega-aminoalcohols replaced
HU9401427D0 (en) 19-nor steroide derivatives, process for producing them and compositions containing them
ZA903139B (en) Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them
PH20421A (en) Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them
HUT55349A (en) Process for producing benzanilide derivatives and pharmaceutical compositions comprising same
HUT49122A (en) Process for producing pharmaceutical compositions containing pyridyl-ethanol-amine as active component and the active component
ATE64374T1 (de) Glutaminsaeurederivate, ihre salze, verfahren zu ihrer herstellung, verwendung als arzneimittel und diese enthaltende zusammensetzungen.
SE8903312L (sv) New 2-carbonyl substituted n,n'-di-(trimethoxybenzol)piperazines, process for preparing the same and therapeutical compounds containing them
ES8306732A1 (es) "un procedimiento para la preparacion de acidos y esteres de aminociclopentanol".
DE3784883T2 (de) Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln.
ES2095831T3 (es) Acidos tetrahidro-4-fenilimino-3-tiofeno-aceticos.
ES2083961T3 (es) Acidos 3-anilino-2-hidroxicarbonil-4-tiofenoaceticos.