ZA902279B - Novel alpha-glucosidase inhibitors - Google Patents

Novel alpha-glucosidase inhibitors

Info

Publication number
ZA902279B
ZA902279B ZA902279A ZA902279A ZA902279B ZA 902279 B ZA902279 B ZA 902279B ZA 902279 A ZA902279 A ZA 902279A ZA 902279 A ZA902279 A ZA 902279A ZA 902279 B ZA902279 B ZA 902279B
Authority
ZA
South Africa
Prior art keywords
glucosidase inhibitors
novel alpha
alpha
novel
glucosidase
Prior art date
Application number
ZA902279A
Other languages
English (en)
Inventor
Jean-Bernard Ducep
Ducep Jean-Bernard
Charles Danzin
Danzin Charles
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA902279B publication Critical patent/ZA902279B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA902279A 1989-03-29 1990-03-23 Novel alpha-glucosidase inhibitors ZA902279B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89400881A EP0389723A1 (en) 1989-03-29 1989-03-29 Novel alpha-glucosidase inhibitors

Publications (1)

Publication Number Publication Date
ZA902279B true ZA902279B (en) 1990-12-28

Family

ID=8202943

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902279A ZA902279B (en) 1989-03-29 1990-03-23 Novel alpha-glucosidase inhibitors

Country Status (10)

Country Link
EP (2) EP0389723A1 (hu)
JP (1) JPH02268154A (hu)
CN (1) CN1045975A (hu)
AU (1) AU5217990A (hu)
CA (1) CA2013382A1 (hu)
FI (1) FI901548A0 (hu)
HU (1) HUT53115A (hu)
NO (1) NO901422L (hu)
PT (1) PT93590A (hu)
ZA (1) ZA902279B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844102A (en) * 1994-07-07 1998-12-01 University Of Maryland Baltimore County Glycohydrolase inhibitors, their preparation and use thereof
JP3043430B2 (ja) * 1995-09-08 2000-05-22 ノボ ノルディスク アクティーゼルスカブ 2−アルキルピロリジン類
US6455573B1 (en) * 2000-01-07 2002-09-24 Simon Fraser University Glycosidase inhibitors and methods of synthesizing same
CN114249718B (zh) * 2021-10-28 2023-09-22 中国药科大学 锍鎓盐类衍生物及其制备方法和医药用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
JPS60193997A (ja) * 1984-03-14 1985-10-02 Sumitomo Chem Co Ltd 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法
US4681873A (en) * 1985-07-29 1987-07-21 Warner-Lambert Company 4-amino-3-halo-2-pyridinone nucleoside and nucleotide compounds
EP0345104B1 (en) * 1988-06-02 1995-11-02 Merrell Dow Pharmaceuticals Inc. Novel Alpha-glucosidase inhibitors

Also Published As

Publication number Publication date
HUT53115A (en) 1990-09-28
FI901548A0 (fi) 1990-03-28
JPH02268154A (ja) 1990-11-01
EP0389723A1 (en) 1990-10-03
AU5217990A (en) 1990-10-04
NO901422L (no) 1990-10-01
EP0390674A1 (en) 1990-10-03
PT93590A (pt) 1990-11-20
HU901879D0 (en) 1990-08-28
CA2013382A1 (en) 1990-09-29
CN1045975A (zh) 1990-10-10
NO901422D0 (no) 1990-03-28

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