ZA897886B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA897886B ZA897886B ZA897886A ZA897886A ZA897886B ZA 897886 B ZA897886 B ZA 897886B ZA 897886 A ZA897886 A ZA 897886A ZA 897886 A ZA897886 A ZA 897886A ZA 897886 B ZA897886 B ZA 897886B
- Authority
- ZA
- South Africa
- Prior art keywords
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888824400A GB8824400D0 (en) | 1988-10-18 | 1988-10-18 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA897886B true ZA897886B (en) | 1990-09-26 |
Family
ID=10645389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA897886A ZA897886B (en) | 1988-10-18 | 1989-10-18 | Heterocyclic compounds |
Country Status (12)
Country | Link |
---|---|
US (1) | US5109008A (xx) |
EP (1) | EP0366327A1 (xx) |
JP (1) | JPH02191278A (xx) |
KR (1) | KR900006341A (xx) |
AU (1) | AU629585B2 (xx) |
CA (1) | CA2000894A1 (xx) |
DK (1) | DK517989A (xx) |
FI (1) | FI894960A0 (xx) |
GB (1) | GB8824400D0 (xx) |
NZ (1) | NZ231056A (xx) |
PT (1) | PT92010A (xx) |
ZA (1) | ZA897886B (xx) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
GB8926560D0 (en) * | 1989-11-24 | 1990-01-17 | Zambeletti Spa L | Pharmaceuticals |
ATE148463T1 (de) * | 1989-11-24 | 1997-02-15 | Smithkline Beecham Spa | N-acyl-substituierte azazyklische verbindungen, verfahren zu deren herstellung und deren verwendung als arzneimittel |
WO1991017116A1 (en) * | 1990-04-28 | 1991-11-14 | Dr. Lo. Zambeletti S.P.A. | Novel 1-(2h-1-oxo-3,4-dihydronaphtyl-6)-acetyl-piperidines, process for their preparation and therapeutic use |
US5122088A (en) * | 1991-01-28 | 1992-06-16 | Meline Ralph E | Mute for an elk call |
GB9104839D0 (en) * | 1991-03-07 | 1991-04-17 | Zambeletti Spa L | Novel compounds |
WO1994002461A1 (en) * | 1992-07-28 | 1994-02-03 | Merck Sharp & Dohme Limited | Azacyclic compounds |
DE4328228A1 (de) * | 1993-08-23 | 1995-03-02 | Basf Ag | Verfahren zur Herstellung von Pyrazol und dessen Derivaten |
IT1273751B (it) * | 1994-02-11 | 1997-07-10 | Smithkline Beecham Farma | Derivati azaciclici |
US5763445A (en) * | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6750216B2 (en) | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
USRE38133E1 (en) * | 1996-03-08 | 2003-06-03 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5688955A (en) * | 1996-03-08 | 1997-11-18 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6303611B1 (en) | 1996-03-08 | 2001-10-16 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
BR9810706A (pt) * | 1997-07-14 | 2000-08-08 | Adolor Corp | Processo para a prevenção ou tratamento do prurido em um mamìfero em necessidade de tal prevenção ou tratamento |
US5760023A (en) * | 1997-07-14 | 1998-06-02 | Adolor Corporation | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith |
KR100295740B1 (ko) | 1998-09-17 | 2001-11-05 | 박영구 | N-치환된-하이드록시고리화알킬아민유도체의제조방법 |
KR100939347B1 (ko) | 2005-07-20 | 2010-01-29 | (주)카이로드 | 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법 |
JP5779100B2 (ja) | 2008-11-24 | 2015-09-16 | カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ | 光学的に活性なn−ベンジル−3−ヒドロキシピロリジンの製造方法 |
NZ731621A (en) | 2009-12-04 | 2019-01-25 | Sunovion Pharmaceuticals Inc | Multicyclic compounds and methods of use thereof |
KR20190065246A (ko) | 2016-07-29 | 2019-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | 화합물 및 조성물 및 이들의 용도 |
IL264446B1 (en) | 2016-07-29 | 2024-05-01 | Pgi Drug Discovery Llc | Compounds and compositions and their use |
IL268694B2 (en) | 2017-02-16 | 2023-10-01 | Sunovion Pharmaceuticals Inc | Treatment of schizophrenia |
EP3661929B1 (en) | 2017-08-02 | 2021-07-14 | Sunovion Pharmaceuticals Inc. | Isochroman compounds and uses thereof |
WO2019161238A1 (en) | 2018-02-16 | 2019-08-22 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
AU2020236225A1 (en) | 2019-03-14 | 2021-09-16 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
US11738002B2 (en) | 2020-04-14 | 2023-08-29 | Sunovion Pharmaceuticals Inc. | Methods of treating neurological and psychiatric disorders |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3845065A (en) * | 1972-02-18 | 1974-10-29 | Merck & Co Inc | 4-oxo-4,5-dihydrothieno(3,2-c)pyridines |
US3903095A (en) * | 1972-02-18 | 1975-09-02 | Merck & Co Inc | Certain substituted-thieno{8 3,2-c{9 -pyridines |
FR2215948B1 (xx) * | 1973-02-01 | 1976-05-14 | Centre Etd Ind Pharma | |
FR2395028A2 (fr) * | 1977-06-22 | 1979-01-19 | Centre Etd Ind Pharma | Derives pyridiniques, leur preparation et leurs application therapeutique |
US4579863A (en) * | 1983-12-06 | 1986-04-01 | Warner-Lambert Company | Substituted trans-1,2-diaminocyclohexyl amide compounds |
US4618621A (en) * | 1984-09-21 | 1986-10-21 | The Upjohn Company | Method for treating medical conditions involving cerebral ischemia |
GB8531615D0 (en) * | 1985-12-23 | 1986-02-05 | Zambeletti Spa L | Compounds |
FR2592879B1 (fr) * | 1986-01-13 | 1988-04-29 | Roussel Uclaf | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant |
GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
DE3767816D1 (de) * | 1986-09-02 | 1991-03-07 | Zambeletti Spa L | 1-acylsubstituierte piperidinderivate. |
EP0271273A3 (en) * | 1986-12-08 | 1989-07-12 | Merck & Co. Inc. | Thieno-and furopyridine sulfonamides |
US4731368A (en) * | 1986-12-08 | 1988-03-15 | Merck & Co., Inc. | Thienopyridine sulfonamides and their ophthalmological formulation |
DK674487A (da) * | 1986-12-22 | 1988-06-23 | Zambeletti Spa L | Piperidinderivater |
FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
ATE97893T1 (de) * | 1988-02-19 | 1993-12-15 | Smithkline Beecham Farma | 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten. |
EP0333427B1 (en) * | 1988-03-16 | 1995-08-23 | Smithkline Beecham Farmaceutici S.p.A. | Heterocyclic derivatives |
-
1988
- 1988-10-18 GB GB888824400A patent/GB8824400D0/en active Pending
-
1989
- 1989-10-16 EP EP89310616A patent/EP0366327A1/en not_active Ceased
- 1989-10-17 CA CA002000894A patent/CA2000894A1/en not_active Abandoned
- 1989-10-17 KR KR1019890014918A patent/KR900006341A/ko not_active Application Discontinuation
- 1989-10-17 PT PT92010A patent/PT92010A/pt unknown
- 1989-10-18 FI FI894960A patent/FI894960A0/fi not_active IP Right Cessation
- 1989-10-18 JP JP1269267A patent/JPH02191278A/ja active Pending
- 1989-10-18 NZ NZ231056A patent/NZ231056A/en unknown
- 1989-10-18 US US07/423,202 patent/US5109008A/en not_active Expired - Fee Related
- 1989-10-18 AU AU42948/89A patent/AU629585B2/en not_active Ceased
- 1989-10-18 ZA ZA897886A patent/ZA897886B/xx unknown
- 1989-10-18 DK DK517989A patent/DK517989A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2000894A1 (en) | 1990-04-18 |
AU4294889A (en) | 1990-04-26 |
US5109008A (en) | 1992-04-28 |
DK517989A (da) | 1990-04-19 |
DK517989D0 (da) | 1989-10-18 |
KR900006341A (ko) | 1990-05-08 |
FI894960A0 (fi) | 1989-10-18 |
EP0366327A1 (en) | 1990-05-02 |
AU629585B2 (en) | 1992-10-08 |
NZ231056A (en) | 1992-02-25 |
GB8824400D0 (en) | 1988-11-23 |
JPH02191278A (ja) | 1990-07-27 |
PT92010A (pt) | 1990-04-30 |
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