ZA897821B - Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- ZA897821B ZA897821B ZA897821A ZA897821A ZA897821B ZA 897821 B ZA897821 B ZA 897821B ZA 897821 A ZA897821 A ZA 897821A ZA 897821 A ZA897821 A ZA 897821A ZA 897821 B ZA897821 B ZA 897821B
- Authority
- ZA
- South Africa
- Prior art keywords
- image
- amino
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- XPKQHJJKXONCHR-UHFFFAOYSA-N 2-amino-3,4-dihydrochromen-2-ol Chemical class C1=CC=C2OC(N)(O)CCC2=C1 XPKQHJJKXONCHR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 102000004257 Potassium Channel Human genes 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004656 alkyl sulfonylamino group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004472 dialkylaminosulfonyl group Chemical group 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 108020001213 potassium channel Proteins 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical class O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000016160 smooth muscle contraction Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8813637A FR2637896B1 (fr) | 1988-10-17 | 1988-10-17 | Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897821B true ZA897821B (en) | 1990-07-25 |
Family
ID=9371088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897821A ZA897821B (en) | 1988-10-17 | 1989-10-16 | Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4999372A (da) |
| EP (1) | EP0365416B1 (da) |
| JP (1) | JPH068296B2 (da) |
| AT (1) | ATE94543T1 (da) |
| AU (1) | AU620157B2 (da) |
| CA (1) | CA2000743A1 (da) |
| DE (1) | DE68909167T2 (da) |
| DK (1) | DK492089A (da) |
| ES (1) | ES2059802T3 (da) |
| FR (1) | FR2637896B1 (da) |
| IE (1) | IE64369B1 (da) |
| NZ (1) | NZ231029A (da) |
| OA (1) | OA09430A (da) |
| PT (1) | PT92007B (da) |
| ZA (1) | ZA897821B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1216461B (it) * | 1988-02-26 | 1990-03-08 | Milano | Derivati del 1_aril solfonil2_pirrolidinone loro procedimentodi preparazione e loro impieto come medicinali. |
| IT1244881B (it) * | 1990-12-13 | 1994-09-12 | Roussel Pharma Spa | Derivati dell'1-arilsolfonil 2-pirrolidone, loro procedimento di preparazione e i nuovi intermedi cosi' ottenuti ,il loro impiego come farmaci e le composizioni farmaceutiche che li contengono |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1495526A (en) * | 1974-05-31 | 1977-12-21 | Beecham Group Ltd | Chroman derivatives |
| DE3579390D1 (de) * | 1984-06-22 | 1990-10-04 | Beecham Group Plc | Wirksame benzopyranverbindungen. |
| GB8625185D0 (en) * | 1986-10-21 | 1986-11-26 | Beecham Group Plc | Active compounds |
| DE3881714D1 (de) * | 1987-02-04 | 1993-07-22 | Hoechst Ag | Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen. |
-
1988
- 1988-10-17 FR FR8813637A patent/FR2637896B1/fr not_active Expired - Lifetime
-
1989
- 1989-10-05 DK DK492089A patent/DK492089A/da not_active Application Discontinuation
- 1989-10-11 US US07/419,824 patent/US4999372A/en not_active Expired - Fee Related
- 1989-10-16 AU AU42872/89A patent/AU620157B2/en not_active Ceased
- 1989-10-16 PT PT92007A patent/PT92007B/pt not_active IP Right Cessation
- 1989-10-16 CA CA002000743A patent/CA2000743A1/fr not_active Abandoned
- 1989-10-16 IE IE331889A patent/IE64369B1/en not_active IP Right Cessation
- 1989-10-16 NZ NZ231029A patent/NZ231029A/xx unknown
- 1989-10-16 ZA ZA897821A patent/ZA897821B/xx unknown
- 1989-10-17 DE DE89402857T patent/DE68909167T2/de not_active Expired - Fee Related
- 1989-10-17 OA OA59664A patent/OA09430A/xx unknown
- 1989-10-17 ES ES89402857T patent/ES2059802T3/es not_active Expired - Lifetime
- 1989-10-17 EP EP89402857A patent/EP0365416B1/fr not_active Expired - Lifetime
- 1989-10-17 AT AT89402857T patent/ATE94543T1/de not_active IP Right Cessation
- 1989-10-17 JP JP1270154A patent/JPH068296B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0365416B1 (fr) | 1993-09-15 |
| ATE94543T1 (de) | 1993-10-15 |
| DE68909167D1 (de) | 1993-10-21 |
| FR2637896A1 (fr) | 1990-04-20 |
| JPH02149578A (ja) | 1990-06-08 |
| DK492089A (da) | 1990-04-18 |
| EP0365416A1 (fr) | 1990-04-25 |
| IE893318L (en) | 1990-04-17 |
| OA09430A (fr) | 1992-10-15 |
| PT92007A (pt) | 1990-04-30 |
| JPH068296B2 (ja) | 1994-02-02 |
| DK492089D0 (da) | 1989-10-05 |
| AU4287289A (en) | 1990-04-26 |
| US4999372A (en) | 1991-03-12 |
| ES2059802T3 (es) | 1994-11-16 |
| AU620157B2 (en) | 1992-02-13 |
| CA2000743A1 (fr) | 1990-04-17 |
| PT92007B (pt) | 1995-06-30 |
| NZ231029A (en) | 1990-10-26 |
| DE68909167T2 (de) | 1994-04-14 |
| IE64369B1 (en) | 1995-07-26 |
| FR2637896B1 (fr) | 1990-11-30 |
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