ZA89440B - Dideoxydidehydrocarbocyclic nucleosides - Google Patents
Dideoxydidehydrocarbocyclic nucleosidesInfo
- Publication number
- ZA89440B ZA89440B ZA89440A ZA89440A ZA89440B ZA 89440 B ZA89440 B ZA 89440B ZA 89440 A ZA89440 A ZA 89440A ZA 89440 A ZA89440 A ZA 89440A ZA 89440 B ZA89440 B ZA 89440B
- Authority
- ZA
- South Africa
- Prior art keywords
- dideoxydidehydrocarbocyclic
- nucleosides
- dideoxydidehydrocarbocyclic nucleosides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/146,252 US4916224A (en) | 1988-01-20 | 1988-01-20 | Dideoxycarbocyclic nucleosides |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA89440B true ZA89440B (en) | 1990-01-31 |
Family
ID=22516514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA89440A ZA89440B (en) | 1988-01-20 | 1989-01-19 | Dideoxydidehydrocarbocyclic nucleosides |
Country Status (5)
Country | Link |
---|---|
US (1) | US4916224A (ru) |
AP (1) | AP91A (ru) |
MX (1) | MX14597A (ru) |
RU (1) | RU2067097C1 (ru) |
ZA (1) | ZA89440B (ru) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN164556B (ru) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
US5521162A (en) * | 1987-08-26 | 1996-05-28 | Merrell Pharmaceuticals Inc. | Aristeromycin analogues of 4',5'-didehydro-5'-fluoro-adenosine and methods of treating neoplastic and viral disease conditions |
US5175292A (en) * | 1988-01-20 | 1992-12-29 | Regents Of The University Of Minnesota | Intermediates for the preparation of dideoxycarbocyclic nucleosides |
US5631370A (en) * | 1988-01-20 | 1997-05-20 | Regents Of The University Of Minnesota | Optically-active isomers of dideoxycarbocyclic nucleosides |
US5015739A (en) * | 1988-04-22 | 1991-05-14 | Schering Corporation | Processes for preparation of cyclopentyl purine derivatives |
US5122517A (en) * | 1988-06-10 | 1992-06-16 | Regents Of The University Of Minnesota | Antiviral combination comprising nucleoside analogs |
GB8815265D0 (en) * | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
US5744600A (en) * | 1988-11-14 | 1998-04-28 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Phosphonomethoxy carbocyclic nucleosides and nucleotides |
US5126347A (en) * | 1989-02-13 | 1992-06-30 | Hoffmann-La Roche Inc. | Isomeric dideoxynuclesides |
US4999428A (en) * | 1989-04-14 | 1991-03-12 | Schering Corporation | Process for preparing cyclopentyl purine derivatives |
JPH04505768A (ja) * | 1990-03-06 | 1992-10-08 | ヴィラケム・インコーポレーテッド | サイトメガロウイルス感染の予防および治療のための方法および組成物 |
US6001840A (en) * | 1990-03-06 | 1999-12-14 | Southern Research Institute | Methods of treatment of viral infections using carbocyclic deoxyguanosine analogs |
US5126452A (en) * | 1990-04-06 | 1992-06-30 | Glaxo Inc. | Synthesis of purine substituted cyclopentene derivatives |
US5144034A (en) * | 1990-04-06 | 1992-09-01 | Glaxo Inc. | Process for the synthesis of cyclopentene derivatives of purines |
US5057630A (en) * | 1990-04-06 | 1991-10-15 | Glaxo Inc. | Synthesis of cyclopentene derivatives |
US5241069A (en) * | 1990-04-06 | 1993-08-31 | Glaxo Inc. | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives |
US5514688A (en) * | 1990-09-14 | 1996-05-07 | Merrell Dow Pharmaceuticals Inc. | Carbocyclic adenosine analogs useful as immunosuppressants |
US5470857A (en) * | 1990-09-14 | 1995-11-28 | Marion Merrell Dow Inc. | Carbocyclic nucleoside analogs useful as immunosuppressants |
US5244896A (en) * | 1990-09-14 | 1993-09-14 | Marion Merrell Dow Inc. | Carbocyclic adenosine analogs useful as immunosuppressants |
GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
US5817660A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817661A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5723466A (en) * | 1991-12-06 | 1998-03-03 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817672A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
KR100337720B1 (ko) | 1993-06-21 | 2002-11-02 | 메렐 파마슈티칼스 인크. | 신규카보사이클릭뉴클레오사이드화합물 |
GB9402161D0 (en) | 1994-02-04 | 1994-03-30 | Wellcome Found | Chloropyrimidine intermediates |
JP2000507552A (ja) * | 1996-03-26 | 2000-06-20 | デュポン ファーマシューティカルズ カンパニー | アリールオキシおよびアリールチオ縮合ピリジン、アリールオキシおよびアリールチオ縮合ピリミジン、およびそれらの誘導体 |
ZA971896B (en) | 1996-03-26 | 1998-09-07 | Du Pont Merck Pharma | Aryloxy-and arythio-fused pyridines and pyrimidines and derivatives |
SK284595B6 (sk) * | 1997-11-27 | 2005-07-01 | Lonza Ag | Spôsob výroby (1S,4R)-4-(2-amino-6-chlór-9H-purín-9-yl)-2- cyklopentén-1-metanolu alebo jeho solí |
KR100606625B1 (ko) | 1998-10-30 | 2006-07-28 | 론자 아게 | 4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법 |
GB9903091D0 (en) * | 1999-02-12 | 1999-03-31 | Glaxo Group Ltd | Therapeutic nucleoside compound |
MY146645A (en) * | 2006-04-21 | 2012-09-14 | Novartis Ag | Purine derivatives for use as adenosin a2a receptor agonists |
WO2008082440A2 (en) * | 2006-08-25 | 2008-07-10 | Emory University | Fluorescent nucleoside analogues |
US8470834B2 (en) * | 2008-08-20 | 2013-06-25 | Merck Sharp & Dohme Corp. | AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3817982A (en) * | 1971-12-29 | 1974-06-18 | Syntex Inc | 2{40 ,3{40 -unsaturated nucleosides and method of making |
US3917837A (en) * | 1974-10-21 | 1975-11-04 | American Cyanamid Co | Method of using trans-2-(6-amino-9H-purin-9-yl)-cyclopentanol |
US4076711A (en) * | 1976-04-05 | 1978-02-28 | Schering Corporation | Triazolo [4,5-d]-pyrimidines |
US4383114A (en) * | 1977-02-09 | 1983-05-10 | Regents Of The University Of Minnesota | Adenosine deaminase resistant antiviral purine arabinonucleosides |
US4223156A (en) * | 1977-02-09 | 1980-09-16 | The Regents Of The University Of Minnesota | Adenosine deaminase resistant antiviral purine nucleosides and method of preparation |
US4138562A (en) * | 1977-02-09 | 1979-02-06 | The Regents Of The University Of Minnesota | Adenosine deaminase resistant antiviral purine nucleosides and method of preparation |
JPS59219284A (ja) * | 1983-05-27 | 1984-12-10 | Toyo Jozo Co Ltd | 3′−デオキシネプラノシンaおよびその製造法 |
US4543255A (en) * | 1984-05-10 | 1985-09-24 | Southern Research Institute | Carbocyclic analogs of purine 2'-deoxyribofuranosides |
FR2574407B1 (fr) * | 1984-12-12 | 1987-06-05 | Rhone Poulenc Sante | Nouveaux derives de la pyrrolo(2,3-d) pyrimidine, leur preparation et les compositions pharmaceutiques qui les contiennent |
US4742064A (en) * | 1985-09-10 | 1988-05-03 | Regents Of The University Of Minnesota | Antiviral carbocyclic analogs of xylofuranosylpurines |
IN164556B (ru) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
EP0277599A3 (en) * | 1987-01-30 | 1990-05-09 | Asahi Glass Company Ltd. | Fluorine containing cyclopentane derivatives and processes for their production |
-
1988
- 1988-01-20 US US07/146,252 patent/US4916224A/en not_active Expired - Lifetime
-
1989
- 1989-01-19 RU SU894613327A patent/RU2067097C1/ru active
- 1989-01-19 ZA ZA89440A patent/ZA89440B/xx unknown
- 1989-01-19 AP APAP/P/1989/000113A patent/AP91A/en active
- 1989-01-19 MX MX1459789A patent/MX14597A/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX14597A (es) | 1993-08-01 |
US4916224A (en) | 1990-04-10 |
RU2067097C1 (ru) | 1996-09-27 |
AP91A (en) | 1990-07-16 |
AP8800113A0 (en) | 1989-01-31 |
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