ZA891696B - Pyrimidinyl-substituted hydroxyacids,lactones and esters and pharmaceutical compositions containing them - Google Patents
Pyrimidinyl-substituted hydroxyacids,lactones and esters and pharmaceutical compositions containing themInfo
- Publication number
- ZA891696B ZA891696B ZA891696A ZA891696A ZA891696B ZA 891696 B ZA891696 B ZA 891696B ZA 891696 A ZA891696 A ZA 891696A ZA 891696 A ZA891696 A ZA 891696A ZA 891696 B ZA891696 B ZA 891696B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxyacids
- lactones
- pyrimidinyl
- esters
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25451488A | 1988-10-06 | 1988-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA891696B true ZA891696B (en) | 1990-11-28 |
Family
ID=22964577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA891696A ZA891696B (en) | 1988-10-06 | 1989-03-06 | Pyrimidinyl-substituted hydroxyacids,lactones and esters and pharmaceutical compositions containing them |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0367895A1 (de) |
| JP (1) | JPH03501613A (de) |
| KR (1) | KR900701778A (de) |
| AU (1) | AU3214689A (de) |
| DK (1) | DK137690A (de) |
| IL (1) | IL89542A0 (de) |
| PH (1) | PH26675A (de) |
| WO (1) | WO1990003973A1 (de) |
| ZA (1) | ZA891696B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3832570A1 (de) * | 1988-09-24 | 1990-03-29 | Hoechst Ag | 7-substituierte derivate der 3,5-dihydroxyhept-6-insaeure, verfahren zur ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte |
| FR2670211B1 (fr) * | 1990-12-11 | 1993-01-22 | Rhone Poulenc Sante | Procede de preparation de derives de l'acide dihydroxy-3,5 oxo-6 hexanouique. |
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
| EP0705837B1 (de) | 1994-09-06 | 2002-08-07 | Ube Industries, Ltd. | Herstellung von 3-oxy-5-oxo-6-Heptensäurederivaten |
| GB0001621D0 (en) * | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| EP1417180B1 (de) | 2001-07-13 | 2006-12-27 | AstraZeneca UK Limited | Herstellung von aminopyrimidinverbindungen |
| GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
| AU2003288443B2 (en) | 2002-12-16 | 2007-10-25 | Astrazeneka Uk Limited | Process for the preparation of pyrimidine compounds |
| GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
| UY28501A1 (es) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
| US7371759B2 (en) | 2003-09-25 | 2008-05-13 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
| GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
| GB0428328D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| US8372877B2 (en) | 2010-04-16 | 2013-02-12 | Cumberland Pharmaceuticals | Stabilized statin formulations |
| CN103153299A (zh) | 2010-10-06 | 2013-06-12 | 国立大学法人东京大学 | 淋巴水肿预防治疗剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3823045A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | 3-desmethyl-mevalonsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen, ihre verwendung sowie zwischenprodukte |
| EP0308736A3 (de) * | 1987-09-12 | 1990-02-14 | Nissan Chemical Industries Ltd. | Pyrimidinyltyp-Mevalonolaktone |
-
1989
- 1989-03-06 EP EP89103931A patent/EP0367895A1/de not_active Withdrawn
- 1989-03-06 WO PCT/EP1989/000225 patent/WO1990003973A1/en unknown
- 1989-03-06 AU AU32146/89A patent/AU3214689A/en not_active Abandoned
- 1989-03-06 JP JP1502939A patent/JPH03501613A/ja active Pending
- 1989-03-06 ZA ZA891696A patent/ZA891696B/xx unknown
- 1989-03-06 KR KR1019900701199A patent/KR900701778A/ko not_active Application Discontinuation
- 1989-03-08 IL IL89542A patent/IL89542A0/xx unknown
- 1989-04-01 PH PH38434A patent/PH26675A/en unknown
-
1990
- 1990-06-01 DK DK137690A patent/DK137690A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL89542A0 (en) | 1989-09-10 |
| DK137690D0 (da) | 1990-06-01 |
| PH26675A (en) | 1992-09-15 |
| WO1990003973A1 (en) | 1990-04-19 |
| KR900701778A (ko) | 1990-12-04 |
| DK137690A (da) | 1990-06-01 |
| AU3214689A (en) | 1990-05-01 |
| JPH03501613A (ja) | 1991-04-11 |
| EP0367895A1 (de) | 1990-05-16 |
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