ZA889710B - 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols - Google Patents
4-aralkyl-5-substituted-1,2,4-triazole-5-thiolsInfo
- Publication number
- ZA889710B ZA889710B ZA889710A ZA889710A ZA889710B ZA 889710 B ZA889710 B ZA 889710B ZA 889710 A ZA889710 A ZA 889710A ZA 889710 A ZA889710 A ZA 889710A ZA 889710 B ZA889710 B ZA 889710B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiols
- triazole
- aralkyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14007487A | 1987-12-31 | 1987-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA889710B true ZA889710B (en) | 1989-12-27 |
Family
ID=22489633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA889710A ZA889710B (en) | 1987-12-31 | 1988-12-29 | 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0323737A1 (ja) |
JP (1) | JPH03501731A (ja) |
AU (1) | AU2948189A (ja) |
WO (1) | WO1989006125A1 (ja) |
ZA (1) | ZA889710B (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ231534A (en) * | 1988-11-29 | 1992-02-25 | Warner Lambert Co | 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions |
EP0409332A3 (en) * | 1989-07-19 | 1991-08-07 | Merck & Co. Inc. | Substituted triazoles as angiotensin ii antagonists |
US5411980A (en) * | 1989-07-28 | 1995-05-02 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists |
DE69024556T2 (de) * | 1989-07-28 | 1996-10-17 | Merck & Co Inc | Substituierte Triazolinone, Triazolinthione und Triazolinimine als Angiotensin II-Antagonisten |
GB9418545D0 (en) * | 1994-09-15 | 1994-11-02 | Merck Sharp & Dohme | Therapeutic agents |
AR039385A1 (es) | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
MXPA06011046A (es) * | 2004-03-26 | 2007-03-21 | Amphora Discovery Corp | Ciertos compuestos basados en triazol, composiciones, y usos de los mismos. |
MY140748A (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
TW200804383A (en) | 2006-06-05 | 2008-01-16 | Astrazeneca Ab | New compounds |
EP3653611A1 (en) * | 2018-11-15 | 2020-05-20 | Centre National De La Recherche Scientifique | Inhibitors of metallo-beta-lactamases |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2097737A5 (en) * | 1970-07-14 | 1972-03-03 | Berlin Chemie Veb | Virustatic 4-substd 1-acylthiosemicarbazides -from carboxylic acid - hydrazide and isothiocyanates or from carboxylic acid chloride and 4- |
US4082762A (en) * | 1975-08-25 | 1978-04-04 | Eli Lilly And Company | 4-(2-halophenyl)-1,2,4-triazole-3-thiol compounds |
US4178253A (en) * | 1977-04-05 | 1979-12-11 | Ciba-Geigy Corporation | Corrosion inhibited lubricant compositions |
DK338179A (da) * | 1978-09-14 | 1980-03-15 | Gulf Oil Corp | 1-benzoyl-3-thiosemicarbazider og anvendelse der i plantevaekstregulerende midler |
US4338453A (en) * | 1980-09-17 | 1982-07-06 | The Upjohn Company | Aminoalkyl-1,2,4-triazoles |
FR2546887B1 (fr) * | 1983-05-30 | 1985-08-30 | Paris 7 Universite | Procede de preparation de dihydro-2,4 triazol-1,2,4 thiones-3 disubstituees en positions 4 et 5 et nouveaux composes pouvant etre prepares par ce procede |
US4481360A (en) * | 1983-08-26 | 1984-11-06 | The Upjohn Company | 4H-1,2,4-Triazol-3-yl compounds |
JPS61165339A (ja) * | 1985-01-16 | 1986-07-26 | Tokuyama Soda Co Ltd | アミド化合物の製造方法 |
US4628059A (en) * | 1985-10-31 | 1986-12-09 | Smithklein Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
JPH0610693Y2 (ja) * | 1986-05-16 | 1994-03-16 | 日本電気株式会社 | Rom実装装置 |
US4761415A (en) * | 1986-08-28 | 1988-08-02 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4900743A (en) * | 1987-01-27 | 1990-02-13 | Merrell Dow Pharmaceuticals Inc. | 3-aryl-5-alkylthio-4H-1,2,4-triazoles |
-
1988
- 1988-12-21 WO PCT/US1988/004578 patent/WO1989006125A1/en unknown
- 1988-12-21 JP JP89501598A patent/JPH03501731A/ja active Pending
- 1988-12-21 AU AU29481/89A patent/AU2948189A/en not_active Abandoned
- 1988-12-22 EP EP88312197A patent/EP0323737A1/en not_active Withdrawn
- 1988-12-29 ZA ZA889710A patent/ZA889710B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1989006125A1 (en) | 1989-07-13 |
EP0323737A1 (en) | 1989-07-12 |
AU2948189A (en) | 1989-08-01 |
JPH03501731A (ja) | 1991-04-18 |
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