ZA889710B - 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols - Google Patents
4-aralkyl-5-substituted-1,2,4-triazole-5-thiolsInfo
- Publication number
- ZA889710B ZA889710B ZA889710A ZA889710A ZA889710B ZA 889710 B ZA889710 B ZA 889710B ZA 889710 A ZA889710 A ZA 889710A ZA 889710 A ZA889710 A ZA 889710A ZA 889710 B ZA889710 B ZA 889710B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiols
- triazole
- aralkyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14007487A | 1987-12-31 | 1987-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA889710B true ZA889710B (en) | 1989-12-27 |
Family
ID=22489633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA889710A ZA889710B (en) | 1987-12-31 | 1988-12-29 | 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0323737A1 (fr) |
JP (1) | JPH03501731A (fr) |
AU (1) | AU2948189A (fr) |
WO (1) | WO1989006125A1 (fr) |
ZA (1) | ZA889710B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ231534A (en) * | 1988-11-29 | 1992-02-25 | Warner Lambert Co | 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions |
EP0409332A3 (en) * | 1989-07-19 | 1991-08-07 | Merck & Co. Inc. | Substituted triazoles as angiotensin ii antagonists |
DE69024556T2 (de) * | 1989-07-28 | 1996-10-17 | Merck & Co Inc | Substituierte Triazolinone, Triazolinthione und Triazolinimine als Angiotensin II-Antagonisten |
US5411980A (en) * | 1989-07-28 | 1995-05-02 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists |
GB9418545D0 (en) * | 1994-09-15 | 1994-11-02 | Merck Sharp & Dohme | Therapeutic agents |
AR039385A1 (es) | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
JP2007530589A (ja) * | 2004-03-26 | 2007-11-01 | アンフォラ ディスカバリー コーポレーション | 特定のトリアゾールを基礎とする化合物、組成物、およびそれらの使用 |
MY140748A (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
TW200804383A (en) | 2006-06-05 | 2008-01-16 | Astrazeneca Ab | New compounds |
EP3653611A1 (fr) * | 2018-11-15 | 2020-05-20 | Centre National De La Recherche Scientifique | Inhibiteurs de metallo-beta-lactamases |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2097737A5 (en) * | 1970-07-14 | 1972-03-03 | Berlin Chemie Veb | Virustatic 4-substd 1-acylthiosemicarbazides -from carboxylic acid - hydrazide and isothiocyanates or from carboxylic acid chloride and 4- |
US4082762A (en) * | 1975-08-25 | 1978-04-04 | Eli Lilly And Company | 4-(2-halophenyl)-1,2,4-triazole-3-thiol compounds |
US4178253A (en) * | 1977-04-05 | 1979-12-11 | Ciba-Geigy Corporation | Corrosion inhibited lubricant compositions |
GR69827B (fr) * | 1978-09-14 | 1982-07-13 | Gulf Oil Corp | |
US4338453A (en) * | 1980-09-17 | 1982-07-06 | The Upjohn Company | Aminoalkyl-1,2,4-triazoles |
FR2546887B1 (fr) * | 1983-05-30 | 1985-08-30 | Paris 7 Universite | Procede de preparation de dihydro-2,4 triazol-1,2,4 thiones-3 disubstituees en positions 4 et 5 et nouveaux composes pouvant etre prepares par ce procede |
US4481360A (en) * | 1983-08-26 | 1984-11-06 | The Upjohn Company | 4H-1,2,4-Triazol-3-yl compounds |
JPS61165339A (ja) * | 1985-01-16 | 1986-07-26 | Tokuyama Soda Co Ltd | アミド化合物の製造方法 |
US4628059A (en) * | 1985-10-31 | 1986-12-09 | Smithklein Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
JPH0610693Y2 (ja) * | 1986-05-16 | 1994-03-16 | 日本電気株式会社 | Rom実装装置 |
US4761415A (en) * | 1986-08-28 | 1988-08-02 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4900743A (en) * | 1987-01-27 | 1990-02-13 | Merrell Dow Pharmaceuticals Inc. | 3-aryl-5-alkylthio-4H-1,2,4-triazoles |
-
1988
- 1988-12-21 AU AU29481/89A patent/AU2948189A/en not_active Abandoned
- 1988-12-21 JP JP89501598A patent/JPH03501731A/ja active Pending
- 1988-12-21 WO PCT/US1988/004578 patent/WO1989006125A1/fr unknown
- 1988-12-22 EP EP88312197A patent/EP0323737A1/fr not_active Withdrawn
- 1988-12-29 ZA ZA889710A patent/ZA889710B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1989006125A1 (fr) | 1989-07-13 |
AU2948189A (en) | 1989-08-01 |
EP0323737A1 (fr) | 1989-07-12 |
JPH03501731A (ja) | 1991-04-18 |
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