ZA889366B - Naphthothiazepinones - Google Patents

Naphthothiazepinones

Info

Publication number
ZA889366B
ZA889366B ZA889366A ZA889366A ZA889366B ZA 889366 B ZA889366 B ZA 889366B ZA 889366 A ZA889366 A ZA 889366A ZA 889366 A ZA889366 A ZA 889366A ZA 889366 B ZA889366 B ZA 889366B
Authority
ZA
South Africa
Prior art keywords
naphthothiazepinones
Prior art date
Application number
ZA889366A
Other languages
English (en)
Inventor
Erno Mohacsi
Mohacsi Erno
Jay Philip O'brien
Philip O'brien Jay
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA889366B publication Critical patent/ZA889366B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
ZA889366A 1987-12-17 1988-12-14 Naphthothiazepinones ZA889366B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/134,282 US4808580A (en) 1987-12-17 1987-12-17 Naphtho[1,2-b][1,4]thiazepin-4(5H)-ones and use thereof in treatment of ischemia and blood pressure lowering

Publications (1)

Publication Number Publication Date
ZA889366B true ZA889366B (en) 1989-08-30

Family

ID=22462636

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA889366A ZA889366B (en) 1987-12-17 1988-12-14 Naphthothiazepinones

Country Status (6)

Country Link
US (1) US4808580A (da)
EP (1) EP0320817A1 (da)
JP (1) JPH01197475A (da)
AU (1) AU2698888A (da)
DK (1) DK695788A (da)
ZA (1) ZA889366B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE61939B1 (en) * 1987-07-31 1994-11-30 Tanabe Seiyaku Co Naphthothiazepine derivatives and a process for preparing the same
WO1991007958A1 (en) * 1989-12-06 1991-06-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Pharmaceutical preparation-protector of myocardium under ischemia and reperfusion
US4992432A (en) * 1990-02-12 1991-02-12 Hoffmann-La Roche Inc. 3-phenyl-thiazepinones as calcium regulating agents
US5112969A (en) * 1990-04-02 1992-05-12 Merrell Dow Pharmaceuticals Inc. Cyano esters and azepinones
DE60020556T2 (de) * 1999-05-12 2005-10-27 Neurosearch A/S Ionenkanal modulierende mittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
IT1206505B (it) * 1983-07-22 1989-04-27 Schiapparelli Farma Nuovi derivati benzotiazepinonici, metodo per la loro preparazione e composizioni farmaceutiche che licontengono.
US4490292A (en) * 1983-10-07 1984-12-25 Hamari Chemicals, Ltd. 1,5-Benzothiazepine derivatives and production thereof
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
US4652561A (en) * 1986-02-26 1987-03-24 Hoffmann-La Roche Inc. Naphtho[1,2-b]-1,4-thiazepinones
IE61939B1 (en) * 1987-07-31 1994-11-30 Tanabe Seiyaku Co Naphthothiazepine derivatives and a process for preparing the same

Also Published As

Publication number Publication date
AU2698888A (en) 1989-06-22
US4808580A (en) 1989-02-28
DK695788A (da) 1989-06-18
EP0320817A1 (de) 1989-06-21
DK695788D0 (da) 1988-12-14
JPH01197475A (ja) 1989-08-09

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