ZA886716B - Combination of phosphodiesterase inhibitor and thromboxane a2 antagonist - Google Patents

Combination of phosphodiesterase inhibitor and thromboxane a2 antagonist

Info

Publication number
ZA886716B
ZA886716B ZA886716A ZA886716A ZA886716B ZA 886716 B ZA886716 B ZA 886716B ZA 886716 A ZA886716 A ZA 886716A ZA 886716 A ZA886716 A ZA 886716A ZA 886716 B ZA886716 B ZA 886716B
Authority
ZA
South Africa
Prior art keywords
thromboxane
antagonist
combination
phosphodiesterase inhibitor
phosphodiesterase
Prior art date
Application number
ZA886716A
Inventor
Johannes Weisenberger
Weisenberger Johannes
Josef Nickl
Nickl Josef
Armin Heckel
Heckel Armin
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA886716B publication Critical patent/ZA886716B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA886716A 1987-09-11 1988-09-09 Combination of phosphodiesterase inhibitor and thromboxane a2 antagonist ZA886716B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9610787A 1987-09-11 1987-09-11

Publications (1)

Publication Number Publication Date
ZA886716B true ZA886716B (en) 1990-05-30

Family

ID=22255374

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886716A ZA886716B (en) 1987-09-11 1988-09-09 Combination of phosphodiesterase inhibitor and thromboxane a2 antagonist

Country Status (7)

Country Link
EP (1) EP0306846A3 (en)
JP (1) JPH01100118A (en)
KR (1) KR890004700A (en)
AU (2) AU2201888A (en)
DK (1) DK500388A (en)
IL (1) IL87721A0 (en)
ZA (1) ZA886716B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0784381B2 (en) * 1989-05-11 1995-09-13 田辺製薬株式会社 Thromboxane A ▲ 2 ▼ Antagonist
JPH0372419A (en) * 1989-05-16 1991-03-27 Tanabe Seiyaku Co Ltd Reversal agent against thromboxane a2
DE4001622A1 (en) * 1990-01-20 1991-07-25 Thomae Gmbh Dr K ORAL DRUGS OF PIMOBENDAN
AU5772396A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
DE102004011512B4 (en) 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical preparation containing pimobendan
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
ES2436716T3 (en) 2008-11-25 2014-01-03 Boehringer Ingelheim Vetmedica Gmbh Pimobendan for use in the treatment of hypertrophic cardiomyopathy in cats
ES2924478T3 (en) 2012-03-15 2022-10-07 Boehringer Ingelheim Vetmedica Gmbh Formulation of pharmaceutical tablets for the veterinary medical sector, method of production and use thereof
CN105377235A (en) 2013-07-19 2016-03-02 勃林格殷格翰动物保健有限公司 Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition
BR112016011111B1 (en) 2013-12-04 2022-11-16 Boehringer Ingelheim Vetmedica Gmbh IMPROVED PHARMACEUTICAL COMPOSITIONS OF PIMOBENDAN
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
KR102199332B1 (en) * 2019-01-30 2021-01-06 한국생산기술연구원 Smart mixing device for confectionery and bakery using multiple mixing bowls with different colors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568676A (en) * 1983-11-25 1986-02-04 Thomas Jefferson University Method of inhibiting aggregation using thromboxane synthetase inhibitor in combination with a cyclic AMP phosphodiesterase inhibitor
FR2596395B1 (en) * 1986-03-26 1989-05-26 Roussel Uclaf NOVEL STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, THEIR PREPARATION METHOD, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
DE3631294A1 (en) * 1986-09-13 1988-03-24 Thomae Gmbh Dr K NEW SYNERGISTIC COMBINATION CONSISTING OF A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A (ARROW DOWN) 2 (ARROW DOWN) ANTAGONISTS AND THEIR USE OR THEIR USE. MANUFACTURING

Also Published As

Publication number Publication date
AU2224688A (en) 1989-03-16
DK500388A (en) 1989-03-12
EP0306846A3 (en) 1990-05-02
KR890004700A (en) 1989-05-09
EP0306846A2 (en) 1989-03-15
AU620341B2 (en) 1992-02-20
AU2201888A (en) 1989-04-27
IL87721A0 (en) 1989-02-28
JPH01100118A (en) 1989-04-18
DK500388D0 (en) 1988-09-09

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