DK500388A - SYNERGISTIC COMBINATION OF A PHOSPHODIESTERASE ANTAGONIST AND A THROMBOXAN-A2 ANTAGONIST AND USE OF SUCH A - Google Patents

SYNERGISTIC COMBINATION OF A PHOSPHODIESTERASE ANTAGONIST AND A THROMBOXAN-A2 ANTAGONIST AND USE OF SUCH A

Info

Publication number
DK500388A
DK500388A DK500388A DK500388A DK500388A DK 500388 A DK500388 A DK 500388A DK 500388 A DK500388 A DK 500388A DK 500388 A DK500388 A DK 500388A DK 500388 A DK500388 A DK 500388A
Authority
DK
Denmark
Prior art keywords
antagonist
thromboxan
phosphodiesterase
synergistic combination
synergistic
Prior art date
Application number
DK500388A
Other languages
Danish (da)
Other versions
DK500388D0 (en
Inventor
Johannes Weisenberger
Josef Nickl
Armin Heckel
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK500388D0 publication Critical patent/DK500388D0/en
Publication of DK500388A publication Critical patent/DK500388A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK500388A 1987-09-11 1988-09-09 SYNERGISTIC COMBINATION OF A PHOSPHODIESTERASE ANTAGONIST AND A THROMBOXAN-A2 ANTAGONIST AND USE OF SUCH A DK500388A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9610787A 1987-09-11 1987-09-11

Publications (2)

Publication Number Publication Date
DK500388D0 DK500388D0 (en) 1988-09-09
DK500388A true DK500388A (en) 1989-03-12

Family

ID=22255374

Family Applications (1)

Application Number Title Priority Date Filing Date
DK500388A DK500388A (en) 1987-09-11 1988-09-09 SYNERGISTIC COMBINATION OF A PHOSPHODIESTERASE ANTAGONIST AND A THROMBOXAN-A2 ANTAGONIST AND USE OF SUCH A

Country Status (7)

Country Link
EP (1) EP0306846A3 (en)
JP (1) JPH01100118A (en)
KR (1) KR890004700A (en)
AU (2) AU2201888A (en)
DK (1) DK500388A (en)
IL (1) IL87721A0 (en)
ZA (1) ZA886716B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0784381B2 (en) * 1989-05-11 1995-09-13 田辺製薬株式会社 Thromboxane A ▲ 2 ▼ Antagonist
JPH0372419A (en) * 1989-05-16 1991-03-27 Tanabe Seiyaku Co Ltd Reversal agent against thromboxane a2
DE4001622A1 (en) * 1990-01-20 1991-07-25 Thomae Gmbh Dr K ORAL DRUGS OF PIMOBENDAN
AU5772396A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
DE102004011512B4 (en) 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical preparation containing pimobendan
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
AU2009319076A1 (en) 2008-11-25 2010-06-03 Boehringer Ingelheim Vetmedica Gmbh Phosphodiesterase type III (PDE III) inhibitors or Ca2+-sensitizing agents for the treatment of hypertrophic cardiomyopathy
ES2924478T3 (en) 2012-03-15 2022-10-07 Boehringer Ingelheim Vetmedica Gmbh Formulation of pharmaceutical tablets for the veterinary medical sector, method of production and use thereof
CN113181110A (en) 2013-07-19 2021-07-30 勃林格殷格翰动物保健有限公司 Liquid aqueous pharmaceutical composition containing preserved etherified cyclodextrin derivatives
EP3106150B1 (en) 2013-12-04 2021-07-28 Boehringer Ingelheim Vetmedica GmbH Improved pharmaceutical compositions of pimobendan
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
KR102199332B1 (en) * 2019-01-30 2021-01-06 한국생산기술연구원 Smart mixing device for confectionery and bakery using multiple mixing bowls with different colors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568676A (en) * 1983-11-25 1986-02-04 Thomas Jefferson University Method of inhibiting aggregation using thromboxane synthetase inhibitor in combination with a cyclic AMP phosphodiesterase inhibitor
FR2596395B1 (en) * 1986-03-26 1989-05-26 Roussel Uclaf NOVEL STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, THEIR PREPARATION METHOD, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM
DE3631294A1 (en) * 1986-09-13 1988-03-24 Thomae Gmbh Dr K NEW SYNERGISTIC COMBINATION CONSISTING OF A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A (ARROW DOWN) 2 (ARROW DOWN) ANTAGONISTS AND THEIR USE OR THEIR USE. MANUFACTURING

Also Published As

Publication number Publication date
AU2201888A (en) 1989-04-27
KR890004700A (en) 1989-05-09
EP0306846A3 (en) 1990-05-02
JPH01100118A (en) 1989-04-18
ZA886716B (en) 1990-05-30
DK500388D0 (en) 1988-09-09
AU2224688A (en) 1989-03-16
IL87721A0 (en) 1989-02-28
AU620341B2 (en) 1992-02-20
EP0306846A2 (en) 1989-03-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment