ZA876806B - Pharmaceutical composition comprising a phosphodiesterase inhibitor and a thromboxane a2 antagonist - Google Patents

Pharmaceutical composition comprising a phosphodiesterase inhibitor and a thromboxane a2 antagonist

Info

Publication number
ZA876806B
ZA876806B ZA876806A ZA876806A ZA876806B ZA 876806 B ZA876806 B ZA 876806B ZA 876806 A ZA876806 A ZA 876806A ZA 876806 A ZA876806 A ZA 876806A ZA 876806 B ZA876806 B ZA 876806B
Authority
ZA
South Africa
Prior art keywords
thromboxane
antagonist
pharmaceutical composition
phosphodiesterase inhibitor
phosphodiesterase
Prior art date
Application number
ZA876806A
Inventor
Walter Haarmann
Haarmann Walter
Josef Nickl
Nickl Josef
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA876806B publication Critical patent/ZA876806B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA876806A 1986-09-13 1987-09-11 Pharmaceutical composition comprising a phosphodiesterase inhibitor and a thromboxane a2 antagonist ZA876806B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863631294 DE3631294A1 (en) 1986-09-13 1986-09-13 NEW SYNERGISTIC COMBINATION CONSISTING OF A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A (ARROW DOWN) 2 (ARROW DOWN) ANTAGONISTS AND THEIR USE OR THEIR USE. MANUFACTURING

Publications (1)

Publication Number Publication Date
ZA876806B true ZA876806B (en) 1989-05-30

Family

ID=6309586

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876806A ZA876806B (en) 1986-09-13 1987-09-11 Pharmaceutical composition comprising a phosphodiesterase inhibitor and a thromboxane a2 antagonist

Country Status (12)

Country Link
EP (1) EP0260527B1 (en)
JP (1) JPS6379838A (en)
KR (1) KR880003624A (en)
AU (1) AU597718B2 (en)
DE (2) DE3631294A1 (en)
DK (1) DK472487A (en)
ES (1) ES2033755T3 (en)
GR (1) GR3004969T3 (en)
IL (1) IL83872A0 (en)
NZ (1) NZ221779A (en)
PH (1) PH23553A (en)
ZA (1) ZA876806B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0306846A3 (en) * 1987-09-11 1990-05-02 Dr. Karl Thomae GmbH Synergistic combination comprising a phosphodiesterase inhibitor and a thromboxane-a2 antagonist, and its use or preparation
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
WO2001021259A2 (en) 1999-09-21 2001-03-29 Emory University Use and compositions for treating platelet-related disorders using anagrelide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291368A (en) * 1979-03-30 1981-09-22 Borg-Warner Corporation Pulse-width modulated inverter system and method
DE3166627D1 (en) * 1980-12-12 1984-11-15 Thomae Gmbh Dr K Pyrimidones, their preparation and medicines containing them
DE3049207A1 (en) * 1980-12-27 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach NEW TRISUBSTITUTED PYRIMIDO (5,4-D) PYRIMIDINE, THEIR PRODUCTION AND USE AS A MEDICINAL PRODUCT
US4568676A (en) * 1983-11-25 1986-02-04 Thomas Jefferson University Method of inhibiting aggregation using thromboxane synthetase inhibitor in combination with a cyclic AMP phosphodiesterase inhibitor

Also Published As

Publication number Publication date
DK472487A (en) 1988-03-14
DK472487D0 (en) 1987-09-10
KR880003624A (en) 1988-05-28
JPS6379838A (en) 1988-04-09
ES2033755T3 (en) 1993-04-01
NZ221779A (en) 1990-03-27
AU597718B2 (en) 1990-06-07
EP0260527A3 (en) 1989-08-09
GR3004969T3 (en) 1993-04-28
IL83872A0 (en) 1988-02-29
EP0260527A2 (en) 1988-03-23
DE3631294A1 (en) 1988-03-24
AU7829687A (en) 1988-03-17
DE3777926D1 (en) 1992-05-07
PH23553A (en) 1989-08-25
EP0260527B1 (en) 1992-04-01

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