DK472487A - SYNERGISTIC COMBINATION CONSISTS OF A PHOSPHORDIESTERASE INHIBITOR AND A THROMBOXAN-A2 ANTAGONIST, ITS APPLICATION AND PREPARATION - Google Patents

SYNERGISTIC COMBINATION CONSISTS OF A PHOSPHORDIESTERASE INHIBITOR AND A THROMBOXAN-A2 ANTAGONIST, ITS APPLICATION AND PREPARATION

Info

Publication number
DK472487A
DK472487A DK472487A DK472487A DK472487A DK 472487 A DK472487 A DK 472487A DK 472487 A DK472487 A DK 472487A DK 472487 A DK472487 A DK 472487A DK 472487 A DK472487 A DK 472487A
Authority
DK
Denmark
Prior art keywords
phosphordiesterase
thromboxan
antagonist
inhibitor
preparation
Prior art date
Application number
DK472487A
Other languages
Danish (da)
Other versions
DK472487D0 (en
Inventor
Walter Haarmann
Josef Nickl
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK472487D0 publication Critical patent/DK472487D0/en
Publication of DK472487A publication Critical patent/DK472487A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK472487A 1986-09-13 1987-09-10 SYNERGISTIC COMBINATION CONSISTS OF A PHOSPHORDIESTERASE INHIBITOR AND A THROMBOXAN-A2 ANTAGONIST, ITS APPLICATION AND PREPARATION DK472487A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863631294 DE3631294A1 (en) 1986-09-13 1986-09-13 NEW SYNERGISTIC COMBINATION CONSISTING OF A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A (ARROW DOWN) 2 (ARROW DOWN) ANTAGONISTS AND THEIR USE OR THEIR USE. MANUFACTURING

Publications (2)

Publication Number Publication Date
DK472487D0 DK472487D0 (en) 1987-09-10
DK472487A true DK472487A (en) 1988-03-14

Family

ID=6309586

Family Applications (1)

Application Number Title Priority Date Filing Date
DK472487A DK472487A (en) 1986-09-13 1987-09-10 SYNERGISTIC COMBINATION CONSISTS OF A PHOSPHORDIESTERASE INHIBITOR AND A THROMBOXAN-A2 ANTAGONIST, ITS APPLICATION AND PREPARATION

Country Status (12)

Country Link
EP (1) EP0260527B1 (en)
JP (1) JPS6379838A (en)
KR (1) KR880003624A (en)
AU (1) AU597718B2 (en)
DE (2) DE3631294A1 (en)
DK (1) DK472487A (en)
ES (1) ES2033755T3 (en)
GR (1) GR3004969T3 (en)
IL (1) IL83872A0 (en)
NZ (1) NZ221779A (en)
PH (1) PH23553A (en)
ZA (1) ZA876806B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0306846A3 (en) * 1987-09-11 1990-05-02 Dr. Karl Thomae GmbH Synergistic combination comprising a phosphodiesterase inhibitor and a thromboxane-a2 antagonist, and its use or preparation
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
EP1216037A2 (en) 1999-09-21 2002-06-26 Emory University Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291368A (en) * 1979-03-30 1981-09-22 Borg-Warner Corporation Pulse-width modulated inverter system and method
EP0054132B1 (en) * 1980-12-12 1984-10-10 Dr. Karl Thomae GmbH Pyrimidones, their preparation and medicines containing them
DE3049207A1 (en) * 1980-12-27 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach NEW TRISUBSTITUTED PYRIMIDO (5,4-D) PYRIMIDINE, THEIR PRODUCTION AND USE AS A MEDICINAL PRODUCT
US4568676A (en) * 1983-11-25 1986-02-04 Thomas Jefferson University Method of inhibiting aggregation using thromboxane synthetase inhibitor in combination with a cyclic AMP phosphodiesterase inhibitor

Also Published As

Publication number Publication date
ES2033755T3 (en) 1993-04-01
DE3631294A1 (en) 1988-03-24
GR3004969T3 (en) 1993-04-28
JPS6379838A (en) 1988-04-09
NZ221779A (en) 1990-03-27
AU597718B2 (en) 1990-06-07
EP0260527A3 (en) 1989-08-09
AU7829687A (en) 1988-03-17
DE3777926D1 (en) 1992-05-07
EP0260527B1 (en) 1992-04-01
DK472487D0 (en) 1987-09-10
EP0260527A2 (en) 1988-03-23
IL83872A0 (en) 1988-02-29
PH23553A (en) 1989-08-25
ZA876806B (en) 1989-05-30
KR880003624A (en) 1988-05-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment