ZA882719B - Use of odc inhibitors,dacarbazine,and interferon in the treatment of malignant melanoma - Google Patents
Use of odc inhibitors,dacarbazine,and interferon in the treatment of malignant melanomaInfo
- Publication number
- ZA882719B ZA882719B ZA882719A ZA882719A ZA882719B ZA 882719 B ZA882719 B ZA 882719B ZA 882719 A ZA882719 A ZA 882719A ZA 882719 A ZA882719 A ZA 882719A ZA 882719 B ZA882719 B ZA 882719B
- Authority
- ZA
- South Africa
- Prior art keywords
- dacarbazine
- interferon
- treatment
- malignant melanoma
- odc inhibitors
- Prior art date
Links
- FDKXTQMXEQVLRF-ZHACJKMWSA-N (E)-dacarbazine Chemical compound CN(C)\N=N\c1[nH]cnc1C(N)=O FDKXTQMXEQVLRF-ZHACJKMWSA-N 0.000 title abstract 2
- 102000014150 Interferons Human genes 0.000 title abstract 2
- 108010050904 Interferons Proteins 0.000 title abstract 2
- 229960003901 dacarbazine Drugs 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 229940079322 interferon Drugs 0.000 title abstract 2
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 title 1
- 201000001441 melanoma Diseases 0.000 title 1
- 239000002818 ornithine decarboxylase inhibitor Substances 0.000 abstract 1
- 229920000768 polyamine Polymers 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4189187A | 1987-04-23 | 1987-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA882719B true ZA882719B (en) | 1988-10-17 |
Family
ID=21918900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA882719A ZA882719B (en) | 1987-04-23 | 1988-04-18 | Use of odc inhibitors,dacarbazine,and interferon in the treatment of malignant melanoma |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0288055B1 (xx) |
| JP (1) | JPS63280019A (xx) |
| KR (1) | KR880012239A (xx) |
| AT (1) | ATE78174T1 (xx) |
| AU (1) | AU609120B2 (xx) |
| DE (1) | DE3872749T2 (xx) |
| DK (1) | DK167905B1 (xx) |
| ES (1) | ES2051788T3 (xx) |
| GR (1) | GR3005553T3 (xx) |
| IE (1) | IE61498B1 (xx) |
| ZA (1) | ZA882719B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0369944A1 (de) * | 1988-11-18 | 1990-05-23 | Ciba-Geigy Ag | Substituierte Oxadiaminobutane |
| IL97759A0 (en) * | 1990-04-11 | 1992-06-21 | Ciba Geigy Ag | Hydroxylamine compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4499072A (en) * | 1982-11-29 | 1985-02-12 | Merrell Dow Pharmaceuticals Inc. | Process for treating diseases with ODC inhibitors |
| US4999072A (en) * | 1987-10-19 | 1991-03-12 | Milliken Research Corporation | Method of making an insole product |
-
1988
- 1988-04-18 ZA ZA882719A patent/ZA882719B/xx unknown
- 1988-04-21 EP EP88106401A patent/EP0288055B1/en not_active Expired - Lifetime
- 1988-04-21 DE DE8888106401T patent/DE3872749T2/de not_active Expired - Fee Related
- 1988-04-21 JP JP63096971A patent/JPS63280019A/ja active Pending
- 1988-04-21 ES ES88106401T patent/ES2051788T3/es not_active Expired - Lifetime
- 1988-04-21 AU AU15023/88A patent/AU609120B2/en not_active Ceased
- 1988-04-21 KR KR1019880004513A patent/KR880012239A/ko not_active Application Discontinuation
- 1988-04-21 AT AT88106401T patent/ATE78174T1/de not_active IP Right Cessation
- 1988-04-22 IE IE122188A patent/IE61498B1/en not_active IP Right Cessation
- 1988-04-22 DK DK222988A patent/DK167905B1/da not_active IP Right Cessation
-
1992
- 1992-08-27 GR GR920401886T patent/GR3005553T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE881221L (en) | 1988-10-23 |
| AU1502388A (en) | 1988-10-27 |
| DK222988A (da) | 1988-10-24 |
| DE3872749D1 (de) | 1992-08-20 |
| EP0288055B1 (en) | 1992-07-15 |
| GR3005553T3 (xx) | 1993-06-07 |
| ES2051788T3 (es) | 1994-07-01 |
| DK167905B1 (da) | 1994-01-03 |
| EP0288055A1 (en) | 1988-10-26 |
| IE61498B1 (en) | 1994-11-02 |
| DK222988D0 (da) | 1988-04-22 |
| JPS63280019A (ja) | 1988-11-17 |
| ATE78174T1 (de) | 1992-08-15 |
| AU609120B2 (en) | 1991-04-26 |
| DE3872749T2 (de) | 1992-12-03 |
| KR880012239A (ko) | 1988-11-26 |
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